Search results for "WEIGHT"

showing 10 items of 2980 documents

The Effect of Bariatric Surgery on Circulating Levels of Lipoprotein (a): A Meta-analysis.

2022

Background. Obesity, especially severe obesity, is associated with a higher risk of atherosclerotic cardiovascular disease (ASCVD) morbidity and mortality. Bariatric surgery is a durable and effective weight loss therapy for patients with severe obesity and weight-related comorbidities. Elevated plasma levels of lipoprotein (a) (Lp(a)) are causally associated with ASCVD. The aim of this meta-analysis was to analyze whether bariatric surgery is associated with Lp(a) concentrations. Methods. A literature search in PubMed, Scopus, Embase, and Web of Science was performed from inception to May 1st, 2021. A random-effects model and the generic inverse variance weighting method were used to compe…

General Immunology and Microbiologylipoprotein obesityWeight LossBariatric SurgeryHumansGeneral MedicineObesityAtherosclerosisGeneral Biochemistry Genetics and Molecular BiologyLipoprotein(a)Obesity MorbidBioMed research international
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Removable singularities for div v=f in weighted Lebesgue spaces

2018

International audience; Let $w\in L^1_{loc}(\R^n)$ be apositive weight. Assuming that a doubling condition and an $L^1$ Poincar\'e inequality on balls for the measure $w(x)dx$, as well as a growth condition on $w$, we prove that the compact subsets of $\R^n$ which are removable for the distributional divergence in $L^{\infty}_{1/w}$ are exactly those with vanishing weighted Hausdorff measure. We also give such a characterization for $L^p_{1/w}$, $1<p<+\infty$, in terms of capacity. This generalizes results due to Phuc and Torres, Silhavy and the first author.

General Mathematics[MATH.MATH-CA]Mathematics [math]/Classical Analysis and ODEs [math.CA]Characterization (mathematics)[MATH.MATH-FA]Mathematics [math]/Functional Analysis [math.FA]01 natural sciencesMeasure (mathematics)functional analysisCombinatoricsMathematics - Analysis of PDEsWeightsRemovable setsClassical Analysis and ODEs (math.CA)FOS: Mathematics[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP]Hausdorff measure0101 mathematicsLp spaceMathematicsremovable singularities010102 general mathematicsta111Divergence operatorMSC 2010: 28A12 42B37Functional Analysis (math.FA)Mathematics - Functional AnalysisMathematics - Classical Analysis and ODEsGravitational singularityweighted Lebesgue spacesfunktionaalianalyysiAnalysis of PDEs (math.AP)
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Nonlocal discrete ∞-Poisson and Hamilton Jacobi equations

2015

In this paper we propose an adaptation of the ∞-Poisson equation on weighted graphs, and propose a finer expression of the ∞-Laplace operator with gradient terms on weighted graphs, by making the link with the biased version of the tug-of-war game. By using this formulation, we propose a hybrid ∞-Poisson Hamilton-Jacobi equation, and we show the link between this version of the ∞-Poisson equation and the adaptation of the eikonal equation on weighted graphs. Our motivation is to use this extension to compute distances on any discrete data that can be represented as a weighted graph. Through experiments and illustrations, we show that this formulation can be used in the resolution of many ap…

Generalized distance[INFO.INFO-TS] Computer Science [cs]/Signal and Image ProcessingTug-of-war gameWeighted graphsPartial difference equations∞-Poisson equation[INFO] Computer Science [cs]Hamilton-Jacobi equation
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Growth rates of F0 and F1 larval and juvenile European seabass Dicentrarchus labrax in resonse to ocean acidification and warming

2022

Ongoing climate change is leading to warmer and more acidic oceans. The future distribution of fish within the oceans depends on their capacity to adapt to these new environments. Only few studies have examined the effects of ocean acidification (OA) and warming (OW) on the metabolism of long-lived fish over successive generations. We therefore aimed to investigate the effect of OA on larval and juvenile growth and metabolism on two successive generations of European sea bass (Dicentrarchus labrax L.) as well as the effect of OAW on larval and juvenile growth and metabolism of the second generation. European sea bass is a large economically important fish species with a long generation time…

GenerationTank numberLife stagedry massType of studyocean warmingjuvenile growthAgeUniform resource locator/link to referenceWeightedDATE TIMEDicentrarchus labraxTreatment temperatureSpeciesbody lengthlarval growthteleostCaliperOcean acidificationTreatment partial pressure of carbon dioxideLaboratory experimentTreatment: temperatureDATE/TIMESample IDTreatment: partial pressure of carbon dioxideDicentrarchus labrax body lengthEarth System Researchmassmetabolic ratesUniform resource locator link to referenceDicentrarchus labrax dry massDicentrarchus labrax mass
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Disrupting immune regulation incurs transient costs in male reproductive function.

2014

9 pages; International audience; BACKGROUND: Immune protection against pathogenic organisms has been shown to incur costs. Previous studies investigating the cost of immunity have mostly focused on the metabolic requirements of immune maintenance and activation. In addition to these metabolic costs, the immune system can induce damage to the host if the immune response is mis-targeted or over-expressed. Given its non-specific nature, an over-expressed inflammatory response is often associated with substantial damage for the host. Here, we investigated the cost of an over-expressed inflammatory response in the reproductive function of male mice. METHODOLOGY/PRINCIPAL FINDINGS: We experimenta…

Genetics and Molecular Biology (all)0106 biological sciencesMalemedicine.medical_treatmentlcsh:MedicineBiochemistry01 natural sciencesMiceMonoclonalReceptorsTestis[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/Symbiosis[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyReceptors Interleukin-10Animals; Antibodies Monoclonal; Body Weight; Inflammation; Male; Mice; Organ Size; Receptors Interleukin-10; Reproduction; Spermatozoa; Testis; Immunomodulation; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)lcsh:ScienceReceptorImmune Response0303 health sciencesMultidisciplinaryReproductive functionMedicine (all)ReproductionAging and ImmunityAntibodies MonoclonalOrgan SizeSpermatozoaInterleukin-103. Good healthCytokineCytokines[SDV.IMM]Life Sciences [q-bio]/Immunologymedicine.symptomResearch ArticleInfertilityEvolutionary ImmunologyImmunologyInflammationBiology010603 evolutionary biologyImmune SuppressionAntibodiesImmunomodulation03 medical and health sciencesImmune systemImmunitymedicineAnimalsBiology030304 developmental biologyInflammationEvolutionary Biology[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologylcsh:RBody WeightImmunityImmunoregulationmedicine.diseaseBlockadeAgricultural and Biological Sciences (all)Immune SystemImmunologyHumoral Immunitylcsh:Q[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular ri…

2016

Background: Intermittent fasting (IF) is an increasingly popular dietary approach used for weight loss and overall health. While there is an increasing body of evidence demonstrating beneficial effects of IF on blood lipids and other health outcomes in the overweight and obese, limited data are available about the effect of IF in athletes. Thus, the present study sought to investigate the effects of a modified IF protocol (i.e. time-restricted feeding) during resistance training in healthy resistance-trained males. Methods: Thirty-four resistance-trained males were randomly assigned to time-restricted feeding (TRF) or normal diet group (ND). TRF subjects consumed 100 % of their energy needs…

Genetics and Molecular Biology (all)0301 basic medicineAdultMalemedicine.medical_specialtyCalorieTime FactorsNormal dietBody builders; Body composition; Fasting; Intermittent fasting; Resistance training; Time-restricted feeding; Medicine (all); Biochemistry Genetics and Molecular Biology (all)Blood lipidsPhysiology030209 endocrinology & metabolismIntermittent fastingOverweightBody buildersBiochemistryBody compositionGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineWeight lossRisk FactorsInternal medicineTime-restricted feedingIntermittent fastingmedicineHumansResting energy expenditureMuscle StrengthCaloric RestrictionMedicine(all)InflammationBiochemistry Genetics and Molecular Biology (all)030109 nutrition & dieteticsbusiness.industryBiochemistry Genetics and Molecular Biology(all)Medicine (all)ResearchResistance TrainingGeneral MedicineFeeding BehaviorFastingEndocrinologyCardiovascular DiseasesBasal metabolic rateBasal Metabolismmedicine.symptomBody builderbusinessJournal of translational medicine
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Impact of Safety-Related Dose Reductions or Discontinuations on Sustained Virologic Response in HCV-Infected Patients: Results from the GUARD-C Cohor…

2015

Background: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings. The non-randomized GUARD-C cohort investigated baseline predictors of safety-related dose reductions or discontinuations (sr-RD) and their impact on sustained virologic response (SVR) in patients receiving peginterferon alfa/ribavirin in routine practice. Methods: A total of 3181 HCV-mono-infected treatment-naive patients were assigned to 24 or 48 weeks of peginterferon alfa/ribavirin by their physician. Patients were categorized by time-to-first sr-RD (Week 4/12). Detailed analyses of the i…

Genetics and Molecular Biology (all)MaleChronic HepatitisHepacivirusRibavirin/adverse effectsAsthenia/chemically inducedHepacivirusPolyethylene GlycolBiochemistryPolyethylene GlycolsBody Mass IndexChronic Liver Disease0302 clinical medicineNeutropenia/chemically inducedInterferon-alpha/adverse effectsMedicineChroniclcsh:ScienceLiver Diseasesvirus diseasesAntiviral Agents/adverse effectsCohortScience & Technology - Other Topics030211 gastroenterology & hepatologyDrug Therapy CombinationCohort studyHumanmedicine.medical_specialtyAlpha interferonGastroenterology and HepatologyAntiviral AgentsMicrobiologyDose-Response Relationship03 medical and health sciencesPharmacotherapyHepatitis C Chronic/drug therapyDose Prediction MethodsDrug TherapyAnemia/chemically inducedHumansHemoglobinAgedMedicine and health sciencesBiochemistry Genetics and Molecular Biology (all)HepaciviruScience & TechnologyDose-Response Relationship DrugFlaviviruseslcsh:ROrganismsBiology and Life SciencesProteinsmedicine.diseasedigestive system diseaseschemistryAgricultural and Biological Sciences (all)Withholding TreatmentAstheniaImmunologyProportional Hazards Modellcsh:QHuman medicineRNA virusesPhysiologylcsh:MedicinePeginterferon-alfaPolyethylene Glycols/adverse effectsAdult; Aged; Anemia; Antiviral Agents; Asthenia; Cohort Studies; Dose-Response Relationship Drug; Drug Therapy Combination; Female; Hepacivirus; Hepatitis C Chronic; Host-Pathogen Interactions; Humans; Interferon-alpha; Male; Middle Aged; Neutropenia; Outcome Assessment (Health Care); Polyethylene Glycols; Proportional Hazards Models; RNA Viral; Recombinant Proteins; Ribavirin; Withholding Treatment; Agricultural and Biological Sciences (all); Biochemistry Genetics and Molecular Biology (all); Medicine (all)Cohort Studieschemistry.chemical_compoundOutcome Assessment Health CareMedicine and Health Sciences030212 general & internal medicineViralPathology and laboratory medicineMultidisciplinarybiologyHepatitis C virusPharmaceuticsMedicine (all)AnemiaHepatitis CHematologyRecombinant ProteinOutcome Assessment (Health Care)/methodsMiddle AgedMedical microbiologyHepatitis CRecombinant ProteinsHost-Pathogen InteractionMultidisciplinary SciencesPhysiological ParametersResearch DesignCombinationHost-Pathogen InteractionsVirusesRNA ViralFemaleDrugPathogensHost-Pathogen Interactions/drug effectsResearch ArticleAdultNeutropeniaClinical Research DesignResearch and Analysis MethodsOutcome Assessment (Health Care)Internal medicineRibavirinRecombinant Proteins/adverse effectsRNA Viral/bloodAdult; Aged; Anemia; Antiviral Agents; Asthenia; Cohort Studies; Dose-Response Relationship Drug; Drug Therapy Combination; Female; Hepacivirus; Hepatitis C Chronic; Host-Pathogen Interactions; Humans; Interferon-alpha; Male; Middle Aged; Neutropenia; Outcome Assessment (Health Care); Polyethylene Glycols; Proportional Hazards Models; RNA Viral; Recombinant Proteins; Ribavirin; Withholding TreatmentAdult; Aged; Anemia; Antiviral Agents; Asthenia; Cohort Studies; Dose-Response Relationship Drug; Drug Therapy Combination; Female; Hepacivirus; Hepatitis C Chronic; Host-Pathogen Interactions; Humans; Interferon-alpha; Male; Middle Aged; Neutropenia; Outcome Assessment (Health Care); Polyethylene Glycols; Proportional Hazards Models; RNA Viral; Recombinant Proteins; Ribavirin; Withholding Treatment; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Proportional Hazards ModelsAntiviral Agentbusiness.industryRibavirinBody WeightHepacivirus/drug effectsViral pathogensInterferon-alphaHepatitis C Chronicbiology.organism_classificationHepatitis virusesMicrobial pathogensRNAAdverse EventsCohort StudiebusinessPloS one
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Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

2018

Background: DNA methylation at the GFI1-locus has been repeatedly associated with exposure to smoking from the foetal period onwards. We explored whether DNA methylation may be a mechanism that links exposure to maternal prenatal smoking with offspring's adult cardio-metabolic health.Methods: We meta-analysed the association between DNA methylation at GFI1-locus with maternal prenatal smoking, adult own smoking, and cardio-metabolic phenotypes in 22 population-based studies from Europe, Australia, and USA (n= 18,212). DNA methylation at the GFI1-locus was measured in whole-blood. Multivariable regression models were fitted to examine its association with exposure to prenatal and own adult s…

Genetics and Molecular Biology (all)MaleNetherlands Twin Register (NTR)0301 basic medicineResearch paperGFI1 protein humanGFI1-locusraskausResearch & Experimental Medicinecardio-metabolic phenotypesBiochemistryEpigenesis GeneticGLOBAL Meth QTL Consortium0302 clinical medicinePregnancySmoke030212 general & internal medicinematernal prenatal smokingDNA METHYLATIONmedia_commonRISK2. Zero hungereducation.field_of_studySmokingta3142General MedicineMiddle Agedgenetics [Transcription Factors]3. Good healthDNA-Binding ProteinsPhenotypeMedicine Research & ExperimentalCARDIOVASCULAR-DISEASEepigenetiikkaPopulation SurveillancePrenatal Exposure Delayed EffectsDNA methylation/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleDisease SusceptibilityBIOS ConsortiumMedical GeneticsLife Sciences & BiomedicineAdultmedicine.medical_specialtyOffspringBirth weightPopulationMothersgenetics [DNA-Binding Proteins]ta3111MethylationGeneral Biochemistry Genetics and Molecular BiologyDIET03 medical and health sciencesMedicine General & InternalSDG 3 - Good Health and Well-beingtupakointiGeneral & Internal MedicineInternal medicine/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_medicinemedia_common.cataloged_instanceHumansddc:610adverse effects [Maternal Exposure]EXPOSUREEpigeneticsEuropean unioneducationMedicinsk genetikEPIGENOME-WIDE ASSOCIATIONPregnancyBiochemistry Genetics and Molecular Biology (all)Science & Technologybusiness.industryadverse effects [Smoking]DNA Methylationta3121medicine.diseaseBIRTH-WEIGHT030104 developmental biologyEndocrinologyGenetic Locisydän- ja verisuonitauditCpG IslandsCIGARETTE-SMOKINGCESSATIONEnergy Metabolismmetabolism [Myocardium]businessBody mass indexBiomarkersTranscription FactorsEBioMedicine
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Factors in Assessing Recidivism Risk in Young Offenders

2020

The research aims to identify if the accumulation of protective and/or risk factors might predict the risk of recidivism in juvenile delinquents and determine the relative weight of both types of factors in the predictions themselves. The risk of criminal recidivism was assessed with the Structured Assessment of Violence Risk in Youth&mdash

Geography Planning and DevelopmentTJ807-830Relative weightManagement Monitoring Policy and LawTD194-195:CIENCIAS ECONÓMICAS [UNESCO]Renewable energy sourcesValencian communityrecidivism riskIntervention (counseling)protective factorsJuvenile delinquencyrisk factorsJuvenileGE1-3500501 psychology and cognitive sciencesadolescentsJustice (ethics)0505 lawEnvironmental effects of industries and plantsRecidivismRenewable Energy Sustainability and the Environment05 social sciencesUNESCO::CIENCIAS ECONÓMICASsustainabilityJuvenile detentionEnvironmental sciences050501 criminologyPsychology050104 developmental & child psychologyClinical psychologySustainability
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Contaminants of emerging concern in freshwater fish from four Spanish Rivers.

2019

This study investigated the occurrence of 135 contaminants of emerging concern (CECs) – pharmaceuticals, pesticides, a set of endocrine disrupting compounds (EDCs) (parabens, bisphenols, hormones, triazoles, organophosphorus flame retardants and triclosan), UV-filters, perfluoroalkyl substances (PFASs) and halogenated flame retardants (HFRs) – in 59 fish samples, collected in 2010 in 4 Spanish Rivers (Guadalquivir, Júcar, Ebro and Llobregat). Of the 135 CECs, 76 including 8 pharmaceuticals, 25 pesticides, 10 EDCs, 5 UV-filters, 15 PFASs and 13 HFRs were detected. Pharmaceuticals were the less frequently found and at lower concentrations. Pesticides, EDCs, UV-filters, PFASs and HFRs were det…

Geologic SedimentsEnvironmental Engineering010504 meteorology & atmospheric sciencesRiver qualityFish consumptionFresh Water010501 environmental sciencesEndocrine DisruptorsAquatic biota01 natural scienceschemistry.chemical_compoundCo-occurrence of contaminantsDry weightAccumulationRiversHalogenated Diphenyl EthersEnvironmental ChemistryAnimals14. Life underwaterPesticidesWaste Management and Disposal0105 earth and related environmental sciencesRisk assessmentFlame RetardantsbiologyChemistryFishesPesticideContaminationbiology.organism_classificationPollution6. Clean waterTriclosanAquatic organisms13. Climate actionSpainEnvironmental chemistryChlorpyrifosFreshwater fishFish <Actinopterygii>Water Pollutants ChemicalEnvironmental MonitoringThe Science of the total environment
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