Search results for "Wald"
showing 10 items of 81 documents
Combined Immuno-Chemotherapy (R-CHOP) Results in Significantly Superior Response Rates and Time to Treatment Failure in First Line Treatment of Patie…
2004
Abstract Lymphomplasmocytoid/ic immunocytoma (LP-IC), including Waldenstrom’s macro-globulinemia and lymphoplasmacytoid lymphoma according to the Kiel classification (the latter one subsummed as a variant of B-CLL in the WHO classification), is an indolent lymphoma, which is incurable by conventional chemotherapy in the advanced stage of disease. The anti-CD20 antibody Rituximab has shown remarkable activity in indolent lymphomas, in particular when combined with chemotherapy. Based on these results the GLSG investigated the efficacy of a combined immuno-chemotherapy (R-CHOP: Rituximab 375 mg/m2 d0-1; cyclophosphamide 750 mg/m2 d1; doxorubicine 50 mg/m2 d1; vincristine 1.4 mg/m2 d1; prednis…
Chronology for the Cueva Victoria fossil site (SE Spain): Evidence for Early Pleistocene Afro-Iberian dispersals
2014
Cueva Victoria has provided remains of more than 90 species of fossil vertebrates, including a hominin phalanx, and the only specimens of the African cercopithecid Theropithecus oswaldi in Europe. To constrain the age of the vertebrate remains we used paleomagnetism, vertebrate biostratigraphy and (230)Th/U dating. Normal polarity was identified in the non-fossiliferous lowest and highest stratigraphic units (red clay and capping flowstones) while reverse polarity was found in the intermediate stratigraphic unit (fossiliferous breccia). A lower polarity change occurred during the deposition of the decalcification clay, when the cave was closed and karstification was active. A second polarit…
Pattern Formation Kinetics for Charged Molecules on Surfaces: Microscopic Correlation Function Analysis
2011
The kinetics of pattern formation and phase separation in a system of two types of oppositely charged molecules with competing short- and long-range interactions on surfaces/interfaces is studied combining three methods: a microscopic formalism of the joint correlation functions, reverse Monte Carlo, and nonequilibrium charge-screening factors. The molecular ordering occurs on the background of the Ostwald ripening and thus is strongly nonequilibrium. We have demonstrated how initial random distribution of molecules is changed for loose similar-molecule aggregates, with further reorganization into dense macroscopic domains of oppositely charged molecules. Pattern formation process is charac…
The “ThreePlusOne” Likelihood-Based Test Statistics: Unified Geometrical and Graphical Interpretations
2014
The presentation of the well known Likelihood Ratio, Wald and Score test statistics in textbooks appears to lack a unified graphical and geometrical interpretation. We present two simple graphical representations on a common scale for these three test statistics, and also the recently proposed Gradient test statistic. These unified graphical displays may favour better understanding of the geometrical meaning of the likelihood based statistics and provide useful insights into their connections.
Revisión de conceptos de las bases anatómicas del espacio retrorrectal y la fascia endopélvica: fascia de Waldeyer y fascia rectosacra
2022
INTRODUCCIÓN La anatomía del recto, localizado en la parte posterior de la cavidad pélvica, supone un reto para los cirujanos colorrectales ya que, aunque anatómicamente representa un área poco extensa, supone, sin embargo, un área con una densidad estructural y funcional muy importantes. Para abordar el espacio retrorrectal y la estructura anatómica que lo limita por delante, el recto, es de primordial interés el dominio anatómico para evitar dañar estructures orgánicas que supongan una elevada morbilidad postoperatoria o una falta de radicalidad oncológica. Por tanto, el minucioso conocimiento anatómico es trascendental para la correcta aplicación de las distintas técnicas quirúrgicas. Pe…
Species of Oswaldella Stechow, 1919 (Cnidaria, Hydrozoa) from recent antarctic expeditions with R.V. 'Polarstern', with the description of eight new …
1997
Twelve species of the genusOswaldellaStechow have been studied, eight of which are new to science [Oswaldella delicatasp. nov.,O. encarnaesp. nov.,O. garciacarrascosaisp. nov.,O. gracilissp. nov.,O. grandissp. nov.,O. incognitasp. nov.,O. obscurasp. nov.andO. rigidasp. nov.], originating from the Weddell Sea and collected by several antarctic expeditions with R.V.Polarstern. Each is described and figured, its systematic position is considered and current data concerning its autecology and geographical distribution are given. Finally, a comparative table is presented including the principal features of all known species of the genus.
Automated Electron Diffraction Tomography
2012
Ab-initio structure analysis by electron diffraction is hampered by two major problems: insufficient number of reflections sampled and an intensity alteration by dynamical scattering contribution or beam damage. Thus, in recent years the principles of automated diffraction tomography (ADT) allowing systematic reciprocal space sampling and automated data analysis were developed. Here the basic ideas of ADT and its general applicability will be discussed along with some examples of solved structures.
Reporting, interpretation, and extrapolation issues (SPIN) in abstracts of orthodontic meta-analyses published from 2000 to 2020
2021
Summary Aim To assess the prevalence of and identify factors associated with SPIN in abstracts of orthodontic meta-analyses. Materials and methods Electronic search was performed within the contents of five orthodontic journals and the Cochrane Database of Systematic Reviews (CDSR) to identify meta-analyses of studies involving humans, from 1 January 2000 until 31 August 2020. Inclusion of SPIN in the abstract of meta-analyses, defined as misleading reporting, misleading interpretation, and inappropriate extrapolation of the findings, was documented. Extent of SPIN and associations with journal and year of publication, type of study, number of authors, continent of authorship, methodologist…
Asymmetric tungsten oxide nanobrushes via oriented attachment and Ostwald ripening
2011
Tungsten oxide nanobrushes were synthesized using a solvothermal approach that lead to self-branching in the presence of citric acid and hexadecylamine as surfactants. Our synthetic approach yielded branched nanorods of tungsten oxide in a single synthetic step. Based on our results, we propose a phenomenological pathway for the formation, branching, and assembly of these tungsten oxide brushes. The formation of tungsten oxide brushes proceeds by thermal decomposition of ammonium tungstate in the presence of citric acid and hexadecylamine. The pale blue powder obtained after solvothermal reaction was analyzed by X-ray diffraction (XRD), transmission electron microscopy (TEM) and high-resolu…
Gibellina, la città che visse due volte : terremoto e ricostruzione nella Valle del Belice
2019
Il passato di Gibellina Nuova non è Gibellina Vecchia. Le storie delle due città sono profondamente diverse: il terremoto del 1968, che colpì con un’intensità del IX grado della scala Mercalli la Valle del Belice, è stato additato come causa della loro soluzione di continuità, ma i veri fattori che hanno determinato una frattura nella continuità storica vanno ricercati nelle politiche di intervento e nelle utopie urbanistiche che hanno orientato la ricostruzione. Il dopo-terremoto del Belice è stato il banco di prova della Prima Repubblica di fronte alle calamità naturali; dal fallimento delle sperimentazioni urbanistiche operate in vivo nel tessuto sociale, dalla dicotomia tra ricostruzion…