Search results for "Wall"

A novel soft robotic pediatric in vitro swallowing device to gain insights into the swallowability of mini-tablets Authors

2022

Perinatal management of gastroschisis

2014

Gastroschisis is an abdominal wall defect, typically located to the right of the umbilical cord, requiring an early surgical treatment shortly after birth. Affected patients can be identified during intrauterine life with US and should be delivered in referral hospitals where a multisciplinary approach can be provided, involving neonatologists, clinical geneticists, surgeons and other specialists. These patients require a complex management in Neonatal Intensive Care Unit (NICU) and a long term follow-up after discharge. Exceed the acute neonatal condition, gastroschisis has a good prognosis, if there are no overlapping complications, and it should be differentiated from omphalocele, burden…

Simulations on the mechanism of CNT bundle growth upon smooth and nanostructured Ni as well as θ-Al2O3 catalysts

2011

Abstract In the current study, we have performed ab initio DFT calculations on the gradually growing 2D periodic models of capped single-wall carbon nanotubes (SW CNTs) upon their perpendicular junctions with the Ni(111) substrate, in order to understand the peculiarities of the initial stage of their growth on either smooth or nanostructured catalytic particles. Appearance of the adsorbed carbon atoms upon the substrate follows from the dissociation of CVD hydrocarbon molecules, e.g., CH4: (CH4)ads → (CH)ads+3Hads and (CH)ads → Cads+Hads. (Since the effective growth of CNTs upon Ni nanoparticles occur inside the nanopores of amorphous alumina, we have also simulated analogous surface react…

Cell Envelopes of Methanogens

2010

Methanogens play an important role in the global carbon cycle, because they are involved in the last step of anaerobic degradation of organic material to methane. Although the first report on methane emanation from aquatic muds was given by Alessandro Volta in the year 1776, the first methanogen was not obtained in pure culture before 1947. Special culture techniques had to be developed for growing the strict anaerobic methanogenic isolates. The methanogens were the first species of the archaeal domain (Archaea) detected. Their unique biochemical and genetic properties have stimulated basic investigations of this microbial group in the last three decades. The methanogenic Archaea possess a …

Understanding moderating effects in increasing share-of-wallet and word-of-mouth : A case study of Lidl grocery retailer

2018

This study examines how five moderating variables (the length of the customer relationship, following a company in print media and on social media, remembering online advertisements, and the customer’s age) affect the relationships between perceived value and loyalty and satisfaction and loyalty in the grocery retailing sector. A series of hypotheses were developed and tested with a sample of 2,072 discount retailer customers in Finland. The results support all the direct effects hypotheses and show that perceived value and satisfaction both have a positive effect on loyalty, measured as a share of wallet and word of mouth and that the effect of perceived value tends to be stronger in the s…

Influence of citrates nanoparticles on morphological traits of bacterial cells pseudomonas syringae pv. atrofaciens

2020

Electron microscope investigations have revealed disintegration of the cell wall of Pseudomonas syringae pv. atrofaciens and subsequent killing of bacterial cells after application of 1% solutions of the citrates of Ag-Cu nanoparticles, the complex Co-Cu-Zn-Fe-Mn-Mo-Mg (Avatar-1) and iodine-selenium. In field conditions, it was revealed that pre-sowing treatment of wheat seeds with the aforementioned 1% solutions significantly inhibited the development of basal glume rot in cereals with artificial infection of Pseudomonas syringae рv. аtrofaciens. Consequently, reduction of the typical symptoms of basal glume rot of cereals and the percentage of isolated cells of Pseudomonas syringae рv. аt…

Anchorage of Candida albicans Ssr1 to the cell wall, and transcript profiling of the null mutant.

2005

Incorporation into the wall of Candida albicans Ssr1, a GPI-dependent protein, was investigated by construction of different truncated genes for which the three potential omega sites (S199, S215 and G216) and the corresponding omega+1 and omega+2 were eliminated or modified. Cells of the C. albicans ssr1Delta mutant were transformed with pADH-pl harboring the truncated versions of CaSSR1, pADH-DeltaCaSSR1t(217-234) (lacking a C-terminal hydrophobic stretch of 18 aa including the putative omega+2 and omega+1, omega+2 of S215 and G216) or pADH-DeltaCaSSR1t(199-201) (lacking three serine residues), and their walls were analyzed for the protein. Results suggested that the three serine residues …

Identification of glucan-mannoprotein complexes in the cell wall of Candida albicans using a monoclonal antibody that reacts with a (1,6)- -glucan ep…

1995

The use of a novel monoclonal antibody (mAb) that reacts with (1,6)-beta-glucan has permitted the study of the different covalent linkages between glucan and mannoproteins in the cell wall of Candida albicans. The mAb JRR1 was originally raised by immunization with Zymolyase extracts from C. albicans cell walls, but it soon became apparent that it reacted with a (1,6)-beta-glucan epitope. By using this antibody, we show the existence of glucan-mannoprotein complexes between the (1,6)-beta-glucan epitope recognized by the antibody and cell wall mannoproteins. The topology of the (1,6)-beta-glucan in the cell wall of C. albicans has also been studied.

Paediatric solid oral dosage forms for combination products: Improving in vitro swallowability of minitablets using binary mixtures with pellets

2023

There is a growing interest in determining and improving the acceptability of solid oral dosage forms (SODF) in paediatric populations. Combination products can be an interesting solution to combine two active pharmaceutical ingredients. This study shows that binary mixture of paediatric SODF could enhance formulation swallowability and palatability. Using the Paediatric Soft Robotic Tongue (PSRT) – an in vitro device inspired by the anatomy and physiology of 2-year-old children – we investigated the oral phase of swallowing of multi-particulate formulations, i.e., pellets (350 and 700 µm particles), minitablets (MTs, 1.8 mm), and their binary mixtures (BM), by measuring the oral swallowing…

Directed Assembly of Cellulose Nanocrystals in Their Native Solid-State Template of a Processed Fiber Cell Wall

2021

Funding Information: I.S. thanks The Academy of Finland (grant no. 300364) for funding this work. C.D. acknowledges funding from FAPESP (grant 13/07932‐6). P.A.P. thanks the Emil Aaltonen Foundation and Academy of Finland (grant no. 315768) for funding and ESRF for beamtime at beamline D2am (experiment 02‐01‐885). Rita Hatakka is acknowledged for her assistance with the GPC measurements. Work of M.L. was supported by the Jane and Aatos Erkko Foundation. The work is a part of the FinnCERES Bioeconomy ecosystem. Publisher Copyright: © 2021 The Authors. Macromolecular Rapid Communications published by Wiley-VCH GmbH Copyright: Copyright 2021 Elsevier B.V., All rights reserved. Nanoparticle ass…