Search results for "Weight"

Age-dependent changes of nuclear envelope protein phosphokinase and protein phosphatase activities. Significance for altered nucleo-cytoplasmic mRNA …

1984

Nuclear envelopes are associated with a protein phosphokinase and a phosphoprotein phosphatase, whose activities are modulated by poly(A) in an opposite manner. The activities of these enzymes were determined in nuclear ghosts from liver and oviduct of quails of different age and of different hormone status. Under optimal conditions, kinase activity was found to increase in immature animals 8-fold in response to diethylstilbestrol; co-administration of progesterone had no marked effect on enzyme activity. After the initial burst, the activity of the enzyme increased only slightly during ageing. Two proteins present in nuclear ghosts of Mr 64 000 and of Mr 106 000 are phosphorylated during t…

P-14ROLE OF TUMOR NECROSIS FACTOR ALPHA IN THE REGULATION OF ALCOHOL DEHYDROGENASE ACTIVITY IN THE LIVER: STUDIES IN OB/OB MICE

2015

Studies suggest that the activity of hepatic ADH is regulated at least in parts by gender, age and body weight. It further has been shown that hormones but also insulin signaling pathways may be involved in ADH activity. However, molecular mechanisms have not yet been fully understood. The aim …

The effects of rapid weight loss on skeletal muscle in judo athletes

2020

Abstract Objective To observe the effect of rapid weight loss (RWL) methods over 3 days on muscle damage in judokas. Methods Eighteen judokas participated in this crossover study, meaning that judo athletes were subjected to exercise-only phase (4 days) and RWL phase (3 days). Subjects were tested for myoglobin, creatine kinase, aldolase, hemoglobin, and hematocrit values on seven consecutive days. These biomarkers served as indicators of acute muscle damage. Results During the exercise-only phase, no significant changes were observed. Myoglobin (Mb) (p < 0.001), creatine kinase (CK) (p < 0.001) and aldolase (ALD) (p < 0.001) significantly increased only during the RWL phase, as we…

Effects of a short-term resistance program using elastic bands versus weight machines for sedentary middle-aged women.

2008

This study was designed to determine whether different effects on functional capacity and body composition were produced by using different devices (elastic bands (EBs) versus weight machines (WMs)) with the same resistance training program. Forty-five healthy sedentary middle-aged women volunteers were chosen and randomly assigned to 1 of 3 groups: 21 subjects trained using EBs (EBG), 14 in trained using WMs (WMG), and 10 were controls (CG). Both exercise groups trained with a periodized muscular endurance program twice a week for 10 weeks, with a total of 6 exercises per session for the major muscle groups. Exercise intensity was equalized by jointly monitoring the same targeted number of…

Evaluation of the Possible Contribution of Antioxidants Administration in Metabolic Syndrome

2011

The metabolic syndrome (MetS) is common, and its associated risk burdens of diabetes and cardiovascular disease (CVD) are a major public health problem. The hypothesis that main constituent parameters of the MetS share common pathophysiologic mechanisms provides a conceptual framework for the future research. Exercise and weight loss can prevent insulin resistance and reduce the risk of diseases associated with the MetS. Interrupting intracellular and extracellular reactive oxygen species (ROS) overproduction could also contribute to normalizing the activation of metabolic pathways leading to the onset of diabetes, endothelial dysfunction, and cardiovascular (CV) complications. On the other…

Biochemical adaptations in middle-distance runners: an assessment of blood and anthropometric parameters

2014

In order to understand the mechanism underlying the physiological adaptation of purely aerobic workout, we investigated the effect of 2 months of training on nine males (17-22 year-old) middle distance running agonistic athletes. Blood sample was collected in the morning to analyze: hematological parameters, lipid profile, liver function enzymes [glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, gamma-glutamyl transferase (γ-GT)] and skeletal and myocardial markers of muscle damage [creatin kinase (CK) and creatin kinase MB (CK-MB)]. Endurance training, as it implies high oxygen consumption, should increase reactive oxygen species, but it has been shown that exercise lea…

Birth weight modifies pulse pressure in children and adolescents

2001

Reduction in aortic compliance in adolescents with suboptimal intrauterine growth

2002

Residual cardiovascular risk of lipid origin. Components and pathophysiological aspects

2019

Abstract There is no doubt about the relationship between LDL-C and cardiovascular risk, as well as about the benefits of statin treatment. Once the objective of LDL-C has been achieved, the evidences that demonstrate the persistence of a high cardiovascular risk, a concept called residual risk, are notable. The residual risk of lipid origin is based on atherogenic dyslipidemia, characterised by an increase in triglycerides and triglyceride-rich lipoproteins, a decrease in HDL-C and qualitative alterations in LDL particles. The most commonly used measures to identify this dyslipidemia are based on the determination of total cholesterol, triglycerides, HDL, non-HDL cholesterol and remaining …

Effects on lipoprotein subclasses of combined expression of human hepatic lipase and human apoB in transgenic rabbits

2003

Objective— The effects of combined expression of human hepatic lipase (HL) and human apolipoprotein B (apoB) on low-density lipoprotein (LDL) subclasses were examined in rabbits, a species naturally deficient in HL activity. Methods and Results— In apoB-transgenic rabbit plasma, >80% of the protein was found in the 1.006- to 1.050-g/mL fraction. Gradient gel electrophoresis (GGE) of this fraction revealed two distinct species, designated large and small LDL. A denser fraction (d=1.050 to 1.063 g/mL) contained small LDL as well as another discrete LDL subspecies, designated very small LDL. Expression of HL resulted in reductions in protein concentrations in the 1.006- to 1.050-g/mL densi…