Search results for "Wester"

Dissolved silica in the Garonne River waters : changes in the weathering dynamics

2000

The major ion chemistry of the Garonne River is indicative of seasonal variations in the weathering dynamics of the drainage basin. Using the geochemical model MEGA for calculation of the contribution of atmospheric CO2 to the total bicarbonate fluxes exported by the Garonne River allows estimations of the concentrations of the major dissolved elements that originate from silicate- and carbonate-rock weathering. The molecular ratio SiO2/Al2O3 was calculated for the 1989–1992 period to identify the main type of weathering in the Garonne River, and montmorillonite was shown to be the major mineral occurring in the weathering products. The seasonal variations of the SiO2/Al2O3 ratio also showe…

Variabilité intra-saisonnière et multi-décennale de la téléconnexion entre les pressions de surface (100°W–50°E ; 30°–70°N) et les ENSO/LNSO (1873–19…

2000

Abstract The relationships between an index of the NINO3.4 region and the wintertime sea level pressure (hereafter SLP) anomalies on the extratropical North Atlantic and the bordering areas (100°W–50°E; 30°–70°N) are studied for 1873–1996. This study emphasizes the need of a careful pooling of months and the multi-decadal variability of the ENSO/LNSO influence on the extratropical North Atlantic. We calculate the mean monthly climate anomalies for the 20 warmest and the 20 coldest NINO3.4 (170°–120°W; 5°N–5°S) years from October to March. The composite of SLP anomalies for the 20 warmest NINO3.4 years shows an anomalous trough centered near 30°W in November–December, and positive (respectiv…

Influence de l'ENSO sur les précipitations de la région à pluies d'hiver d’Afrique du sud.

2012

5 pages; International audience; L'impact de l'ENSO sur la région à pluies d'hiver d'Afrique du Sud a été peu étudié, alors qu’il s’agit d’une zone densément peuplée, grosse exportatrice de produits agricoles, et par ailleurs remarquable par sa biodiversité. La relation ENSO - précipitations d'hiver est analysée à partir de 682 pluviomètres sur la période 1950-1999. Le cumul saisonnier mai-juillet (MJJ) est corrélé positivement et significativement à l'ENSO depuis la rupture climatique de 1976/1977. Les forts cumuls de MJJ durant les événements ENSO résultent de séquences humides plus longues dans la région du Cap et plus fréquentes dans la région au nord de 33°S. Les séquences humides enre…

Paris Biota: At the dawn of modern marine faunas?

2021

In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent.

2015

International audience; Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy derived from plasmacytoid dendritic cells. There is currently no accepted standard of care for treating this neoplasm, and therapeutic strategies have never been prospectively evaluated. Since blastic plasmacytoid dendritic cell neoplasm cells express high levels of interleukin-3 receptor α chain (IL3-Rα or CD123), antitumor effects of the interleukin-3 receptor-targeted drug SL-401 against blastic plasmacytoid dendritic cell neoplasm were evaluated in vitro and in vivo. The cytotoxicity of SL-401 was assessed in patient-derived blastic plasmacytoid dendritic cell neoplasm cell lines (CAL-1 and …

Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts

2014

International audience; Background: Inborn enzyme defects of mitochondrial fatty acid beta-oxidation (FAO) form a large group of genetic disorders associated to variable clinical presentations ranging from life-threatening pediatric manifestations up to milder late onset phenotypes, including myopathy. Very few candidate drugs have been identified in this group of disorders. Resveratrol (RSV) is a natural polyphenol with anti-oxidant and anti-inflammatory effects, recently shown to have beneficial metabolic properties in mice models. Our study explores its possible effects on FAO and mitochondrial energy metabolism in human cells, which are still very little documented.Methods: Using cells …

Anza palaeoichnological site, Late Cretaceous, Morocco. Part III: Comparison between traditional and photogrammetric records

2020

11 pages; International audience; The present study evaluates a methodological workflow that could identify dinosaur tracks and trackways more comprehensively at outcrop scale. The approach described here is based both on 3D modelling by photogrammetry at different resolutions, and on suitably processed digital elevation models (DEMs). The ichnosite of Anza, Morocco, was chosen to demonstrate the efficiency of the proposed pipeline, because 323 dinosaur and pterosaur tracks discovered there have already been published. One subsector containing 89 tracks, identified in the two companion works that followed a traditional approach, was selected and divided into four subzones. By combining diff…

A genre and a limit: Across the Rio Grande border: A study of Tommy Lee Jones' 2005 film "The Three Burials of Melquiades Estrada"

2010

Attempting to answer the deceptively simple question of how far Tommy Lee Jones' 2005 film "The Three Burials of Melquiades Estrada" can be described as a western will give an opportunity to explore some features of the genre, especially the geography of the Western, as well as study a few stories set in typical landscapes, focussing on the border between the United States and Mexico. That major locus in northern as well as mid-American imagination and culture is also the setting of a number of westerns and especially of John Ford's Rio Grande (1950), the source of our title as well as a fascinating inter-text to Tommy Lee Jones' work. A post mortem western, The Three Burials of Melquiades …

"More or Less American: Sergio Leone's Vision of America in 'Once Upon a Time in the West' (1968)"

2012

This article focuses on the representation of the American West in Sergio Leone's fourth Western, which is the first to include several scenes that have been shot on location in the U.S. The author argues that Once Upon a Time in the West offers a critique not only of the classical Hollywood Westerns Leone adored, but also of his own brand of Italian Western, which may, in part, explain why members of the counter-culture were so enthused by the film at its release. The first section examines the way the use of American locations foregrounds the artificiality of Leone's spatial construction. The second explores the political implications of the inclusion of various minority groups, thereby r…

Public employees in South-Western Norway using an e-bike or a regular bike for commuting – A cross-sectional comparison on sociodemographic factors, …

2019

Large-scale analyses on the travel behavior of e-bikes are scarce, and current knowledge regarding who the e-bike owners are is inconsistent. Also, commuters represent a relevant user group with an unexploited potential. Therefore, the purpose of the present study was to examine (i) associations between type of bike (e-bike vs. regular bike) with place of residence (county), sociodemographic variables (age, sex, educational level, income and ethnicity) and habitual physical activity level, and (ii) if public employees possessing an e-bike cycle more often and longer distances to work. A cross-sectional survey was conducted in 2017 among 1977 (5.2% of eligible subjects) public employees in S…