Search results for "Wester"
showing 10 items of 1157 documents
Hsa-miR-30d, secreted by the human endometrium, is taken up by the pre-implantation embryo and might modify its transcriptome.
2015
During embryo implantation, the blastocyst interacts with and regulates the endometrium, and endometrial fluid secreted by the endometrial epithelium nurtures the embryo. Here, we propose that maternal microRNAs (miRNAs) might act as transcriptomic modifier of the pre-implantation embryo. Microarray profiling revealed that six of 27 specific, maternal miRNAs were differentially expressed in the human endometrial epithelium during the window of implantation – a brief phase of endometrial receptivity to the blastocyst – and were released into the endometrial fluid. Further investigation revealed that hsa-miR-30d, the expression levels of which were most significantly upregulated, was secreted…
Anti-PR-3 antibodies induce endothelial IL-8 release
1999
Background It has been shown that interaction of anti-PR-3 antibodies with human endothelial cells (EC) leads to an activation of EC in vitro, i.e. induction of adhesion molecules like E-selectin, VCAM-1 and tissue factor. The aim of this study was to investigate the effect of anti-PR-3 antibodies on endothelial IL-8 expression. Materials and methods EC were cultured in 96-well plates and stimulated with TNF-α and IL-1β for 1 h to induce membrane expression of endothelial PR-3. Anti-PR-3 antibodies were purified from sera from patients with clinically active Wegener's granulomatosis. Purified anti-Ro, anti-centromere, anti-dsDNA antibodies and a monoclonal anti-PR-3 antibody (WGM2) served a…
<title>Tradeoff between environmental impacts and economic benefits?: A case study of the Finnish and British pulp and paper industries</tit…
2001
Due to the increased used paper collection rates in Western Europe, more recycled fibre will be used in the manufacture of paper. This will affect both the environmental and economic performance of the pulp and paper industry. The potential for the increase of the collection rate varies significantly in different countries in western Europe. In some countries the collection rate is already close to 70% (Austria, Germany) and in others it is around 45% (Italy, United Kingdom). With the increased demand for recycled fibre also the collection will increase. When the collection of waste paper is increased something has to be done with the collected paper. Different utilisation modes results in …
Conclusion: Hospitality in the New Millennium
2017
The main thesis held here is that Western civilization has subscribed to a medical / surgical metaphor, which consists in extirpating the affected part to save the body. If this is applied in the case of terrorism, the Muslim community runs serious risk of being demonized and martyrized in the name of security.
Faut-il provincialiser les Lumières
2013
OS nat; National audience; no abstract
CLA-Enriched Diet Containing t10,c12-CLA Alters Bile Acid Homeostasis and Increases the Risk of Cholelithiasis in Mice
2011
International audience; Mice fed a mixture of CLA containing t10,c12-CLA lose fat mass and develop hyperinsulinemia and hepatic steatosis due to an accumulation of TG and cholesterol. Because cholesterol is the precursor in bile acid (BA) synthesis, we investigated whether t10,c12-CLA alters BA metabolism. In Expt. 1, female C57Bl/6J mice were fed a standard diet for 28 d supplemented with a CLA mixture (1 g/100 g) or not (controls). In Expt. 2, the feeding period was reduced to 4, 6, and 10 d. In Expt. 3, mice were fed a diet supplemented with linoleic acid, c9,t11-CLA, or t10,c12-CLA (0.4 g/100 g) for 28 d. In Expt. 1, the BA pool size was greater in CLA-fed mice than in controls and the …
Why Study the Spread of Culture-led Development Strategies?
2012
Culture, entertainment and amenities as urban and regional development policies have received much attention over the last decade. In the wake of recent work on the creative class, culture-led development policies have been applied in cities and regions across the Western world. This article uses quantitative data to examine whether these policies have gained the support of Scandinavian local and regional politicians and, if so, why and how. Drawing on policy diffusion and policy transfer theory, the article examines from where politicians are influenced. Can the sources of influence be characterized as (1) horizontal, (2) top-down or (3) bottom-up? The main finding is that the top-down per…
Quantifying submarine groundwater discharge in the coastal zone via multiple methods
2006
Submarine groundwater discharge (SGD) is now recognized as an important pathway between land and sea. As such, this flow may contribute to the biogeochemical and other marine budgets of near-shore waters. These discharges typically display significant spatial and temporal variability making assessments difficult. Groundwater seepage is patchy, diffuse, temporally variable, and may involve multiple aquifers. Thus, the measurement of its magnitude and associated chemical fluxes is a challenging enterprise. A joint project of UNESCO and the International Atomic Energy Agency (IAEA) has examined several methods of SGD assessment and carried out a series of five intercomparison experiments in di…
Construction of an agglutination tool: recombinant Fab fragments biotinylated in vitro.
2009
The pComb3H vector system is used for constructing and panning recombinant antibody libraries. It allows for expression of monovalent Fab fragments, either on the surface of M13 phage, or in the form of soluble proteins secreted into the periplasmic space of bacteria. We constructed a modified pComb3H vector containing cDNA encoding for a 23-amino acid fragment of the Escherichia coli biotin carboxy carrier protein (BCCP), which is an acceptor sequence for biotinylation. The vector was used to express the Fab fragment recognizing human glycophorin A. The purified Fab fragment containing this biotin acceptor sequence was effectively biotinylated in vitro using biotin ligase (BirA). The speci…
The Other in Western Civilization
2017
This chapter explores how the Otherness was imagined by Europeanness, as well as the stereotypes, prejudices and idealized image around the non-Western Other. This section not only discusses to what extent Europe launched to colonize the world but the socio-cultural background for the European proclamation of supremacy over the rest of the world. The perverse core of European ethnocentrism rests in its paternalism to understand the cultural difference, adjoined to the rise and consolidation of Science, which paradoxically accelerated what David Riesman dubbed ‘the Other-oriented’ gaze. This is the moment of great technological breakthrough and the flourishing of romantic novels, literature …