Search results for "Wild"

showing 10 items of 542 documents

Anti-inflammatory Function of High-Density Lipoproteins via Autophagy of IκB Kinase

2015

Background & Aims: Plasma levels of high-density lipoprotein (HDL) cholesterol are frequently found decreased in patients with inflammatory bowel disease (IBD). Therefore, and because HDL exerts anti-inflammatory activities, we investigated whether HDL and its major protein component apolipoprotein A-I (apoA-I) modulate mucosal inflammatory responses in vitro and in vivo. Methods: The human intestinal epithelial cell line T84 was used as the in vitro model for measuring the effects of HDL on the expression and secretion of tumor necrosis factor (TNF), interleukin-8 (IL-8), and intracellular adhesion molecule (ICAM). Nuclear factor-κB (NF-κB)-responsive promoter activity was studied by …

WT wild typeApolipoprotein BEMSA electrophoretic mobility shift assayMPO myeloperoxidaseIκB kinaseDSS dextran sodium sulphatemTOR the mammalian target of rapamycinRT-PCR real-time polymerase chain reactionNF-κBchemistry.chemical_compound540 ChemistryApoA-I apolipoprotein A-I10038 Institute of Clinical ChemistryOriginal ResearchTNF tumor necrosis factorbiologyIBD inflammatory bowel diseaseChemistryGastroenterologyMyeloperoxidase10076 Center for Integrative Human PhysiologyMEICS murine endoscopic index of colitis severityTumor necrosis factor alphalipids (amino acids peptides and proteins)3-MA 3-methyl adenineNF-κB nuclear factor κBHDL high-density lipoproteinLC3II light chain 3 IIPBS phosphate-buffered salinep-IKK phosphorylated IκB kinase610 Medicine & healthICAM intracellular adhesion molecule246-Trinitrobenzenesulfonic acidTg transgenicmedicineAutophagyCD Crohn’s disease2715 GastroenterologyColitislcsh:RC799-869KO knockoutHepatologyApolipoprotein A-IAutophagyInflammatory Bowel DiseaseTNBS 246-trinitrobenzenesulfonic acidmedicine.diseaseMolecular biologyIL interleukinsiRNA small interfering RNAPI-3 phosphatidylinositol-3Immunologybiology.protein2721 Hepatologylcsh:Diseases of the digestive system. GastroenterologyPFA paraformaldehydeLipoproteinDAPI 4′6-diamidino-2-phenylindoleCMGH Cellular and Molecular Gastroenterology and Hepatology
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Mosaic activating mutations in GNA11 and GNAQ are associated with phakomatosis pigmentovascularis and extensive dermal melanocytosis

2016

Common birthmarks can be an indicator of underlying genetic disease but are often overlooked. Mongolian blue spots (dermal melanocytosis) are usually localized and transient, but they can be extensive, permanent, and associated with extracutaneous abnormalities. Co-occurrence with vascular birthmarks defines a subtype of phakomatosis pigmentovascularis, a group of syndromes associated with neurovascular, ophthalmological, overgrowth, and malignant complications. Here, we discover that extensive dermal melanocytosis and phakomatosis pigmentovascularis are associated with activating mutations in GNA11 and GNAQ, genes that encode Gα subunits of heterotrimeric G proteins. The mutations were det…

WT wild typeDNA Mutational AnalysisMolecular Sequence Datapostzygotic mutationsMutation MissenseSWS Sturge-Weber syndromeDermatologycesioflammeagermlineBiochemistrySkin DiseasesAnimals Genetically Modifiedg-proteinDNA deoxyribonucleic acidMongolian Spotoculodermal melanocytosis[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyGeneticsAnimalsHumansddc:610Phosphorylationchoroidal melanomaMolecular BiologyAllelesZebrafishdiseaseBase SequenceNeurocutaneous Syndromessturge-weberInfantCell Biologymongolian spotPPV phakomatosis pigmentovascularisGTP-Binding Protein alpha SubunitsHEK293 CellsPhenotypeMutationGTP-Binding Protein alpha Subunits Gq-G11Original Articleuveal melanoma[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologySignal Transduction
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Intensity and persistence of water repellency at different soil moisture contents and depths after a forest wildfire

2022

Abstract The Mediterranean mixed coniferous and broad-leaved forest of Moarda (Palermo) was affected by a large wildfire in summer 2020. In spring 2021, burned and unburned loam soil sites were sampled and the water drop penetration time (WDPT) and ethanol percentage (EP) tests applied to assess the influence of wetting-drying processes and soil water content on post-fire soil water repellency (SWR) as well as its vertical distribution. According to the WDPT test, the surface layer of the natural unburned soils was severely hydrophobic at intermediate soil water contents roughly corresponding to wilting point and SWR reduced either for very dry conditions (air- or oven-dried conditions) or …

Water drop penetration time testSoil water repellencyEthanol percentage testSettore AGR/04 - Orticoltura E FloricolturaWildfireJournal of Hydrology and Hydromechanics
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Identification and sustainable exploitation of wild edible mushrooms in rural areas (Mycoticon, LdV-ToI project): Development of an innovative traini…

2015

In Mediterranean and in southeast Europe the activities of a significant part of the population are traditionally linked with agriculture, forestry and animal husbandry. However, many rural communities are experiencing serious difficulties associated with low income per person and poor employment prospects combined with increased demographic decline. Alternative activities such as the collection and trading of wild edible mushrooms as well as the cultivation of choice species could contribute at providing valuable solutions both in financial and environmental terms. The total number of fungal species which are considered having edible and/or medicinal value is over 2300.1 Most of them form …

Wild edible mushrooms rural areas South EuropeSettore BIO/03 - Botanica Ambientale E Applicata
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Man's strategy in domestication - a synthesis of new research trends.

1976

The minimum brain size possible in the relevant wild species and certain colour types which, because of alterations in the neurotransmitter system caused by the respective colour genes, are related to behavioural traits diverging from the wild animal's norm appear to be first-rate bases for domestication either separately or in combination.

Wild speciesLitter SizeZoologyBiologyCellular and Molecular NeuroscienceDogsPregnancyAnimalsAnimal HusbandryDomesticationMolecular BiologyGeneArtiodactylaPharmacologyBehavior AnimalBody WeightBrainCell BiologyOrgan SizeBiological EvolutionRatsAnimals DomesticBrain sizeCatsMolecular MedicineFemaleExperientia
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Competitive selection in mono-, di- and tri-genotype cultures of Drosophila melanogaster

2009

Viability and larva-to-adult development of three strains of Drosophila melanogaster (one wild strain and two eye mutant strains: cardinal and sepia) were studied under three different situations: A. Monocultures of wild, cardinal and sepia respectively. B. Dicultures with the combinations wild/cardinal, wild/sepia and cardinal/sepia respectively. Seven points of different genetical composition were chosen for each of the three systems. C. Tricultures with wild/cardinal/sepia. Seventy composition points were chosen. The points arranged in a three dimensional diagram with the axes wild, cardinal and sepia, make up an equilateral triangle hyperplane. An analysis of optimal density and intrins…

Wild strainOptimal densitybiologyGenotypeGeneticsStable equilibriumAnimal Science and ZoologySepiaDrosophila melanogasterbiology.organism_classificationMolecular BiologyMolecular biologyEcology Evolution Behavior and SystematicsJournal of Zoological Systematics and Evolutionary Research
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Show me your tail, if you have one! Is inbreeding depression occurring in wildcats (Felis silvestris silvestris) from Italy?

2022

Knowledge of genetic diversity is important to wildlife conservation because genetically depleted populations experience an increased risk of extinction. Mammalian carnivores are characterized by small and fragmented populations and low dispersal, so that genetic erosion can lead to the fixation of deleterious genes relatively quickly, leading to morphological abnormalities. Kinked tails and cowlicks are indicative of inbreeding depression and have been described in two wild cat species so far, the puma (Puma concolor) and the cheetah (Acinonyx jubatus). Here we report the first records of morphological abnormalities in five populations of the European wildcat (Felis silvestris silvestris) …

WildcatsKinked tailsBrachyuria; Cowlicks; Genetic diversity; Inbreeding depression; Kinked tails; WildcatsBrachyuriaAnimal Science and ZoologyCowlicksInbreeding depressionGenetic diversityEcology Evolution Behavior and SystematicsMammal Research
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Provokaatiota ja estetismiä

2008

Wilde Oscarkirja-arvostelutphilosophy of literatureestetismi (aatteet)dandismitaideOscar Wildetaidefilosofiaestetiikkataidekritiikki1800-luku
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Cervico-Oculo-Acusticus (Wildervanck's) syndrome: a clinical variant of Klippel-Feil sequence?

1990

A 7-year-old female child with phenotype of Cervico-Oculo-Acousticus (Wildervanck's) syndrome is presented. In addition to fusion of multiple cervical vertebrae with short neck, abducens nerve palsy and deafness, the child showed severe growth and bone delay, renal abnormalities and slight mental retardation. The presence of such malformations seems to suggest that Wildervanck's syndrome is a clinical variant of Klippel-Feil sequence. Both conditions usually have sporadic occurrence with female prevalence, more consistent for cervico-oculo-acousticus syndrome. The possibility of dominant inheritance has been postulated for both, autosomal for Klippel-Feil, autosomal or X-linked with lethali…

Wildervanck's syndromemedicine.medical_specialtyPathologyKlippel–Feil syndromeDeafnessWildervanck syndromeInternal medicinemedicineHumansAbnormalities MultipleChildAbducens nerveGenes DominantSequence (medicine)OphthalmoplegiaPalsybusiness.industrySyndromemedicine.diseasePhenotypePhenotypeEndocrinologyKlippel-Feil SyndromePediatrics Perinatology and Child HealthEtiologyFemalebusinessKlinische Pädiatrie
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Conservation of Ptilostemon greuteri (Asteraceae), an endemic climate relict from Sicily (Italy): state of knowledge after the discovery of a second …

2022

Ptilostemon greuteri is one of the most endangered and poorly studied woody vascular plant species of the Mediterranean Basin, endemic to Sicily (Italy). Several peculiar traits confer to P. greuteri a character of uniqueness and an enigmatic attractiveness. In fact, at first glimpse the largest individuals of this species remind the most remarkable and peculiar cases of herbaceous genera (e.g., Echium, Senecio) turned woody on insular or insular-like mountain ecosystems. Following the discovery of a second population of this rare species, a project aiming at the study and conservation of P. greuteri was set up. We present here updated information on the distribution, conservation status, b…

WoodinessEcologyConservation BiologyConservation biologyEndemismIUCN Red List assessmentMicro-topographyWildfiresWoodinessMicrotopographyWildfireEcology Evolution Behavior and SystematicsNature and Landscape ConservationEndemismIUCN Red List assessment
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