Search results for "Wings"
showing 10 items of 93 documents
Dendrites are dispensable for basic motoneuron function but essential for fine tuning of behavior.
2014
Dendrites are highly complex 3D structures that define neuronal morphology and connectivity and are the predominant sites for synaptic input. Defects in dendritic structure are highly consistent correlates of brain diseases. However, the precise consequences of dendritic structure defects for neuronal function and behavioral performance remain unknown. Here we probe dendritic function by using genetic tools to selectively abolish dendrites in identified Drosophila wing motoneurons without affecting other neuronal properties. We find that these motoneuron dendrites are unexpectedly dispensable for synaptic targeting, qualitatively normal neuronal activity patterns during behavior, and basic …
optomotor-blind suppresses instability at the A/P compartment boundary of the Drosophila wing.
2008
Formation and function of the A/P compartment boundary of the Drosophila wing have been studied intensely. The boundary prevents mingling of A and P cells, is characterized by an expression discontinuity of several genes like engrailed, Cubitus interruptus, hedgehog and decapentaplegic and is essential for patterning the wing. Compared with segmental or compartmental boundaries in several other systems which generally manifest as folds or clefts, the wing A/P boundary is morphologically inconspicuous in both the larval and adult stage. We show here that the Drosophila wing A/P boundary, too, is susceptible to fold and cleft formation and that these processes are suppressed by the T-box tran…
Spatial discontinuity of Optomotor-blind expression in the Drosophila wing imaginal disc disrupts epithelial architecture and promotes cell sorting
2010
Abstract Background Decapentaplegic (Dpp) is one of the best characterized morphogens, required for dorso-ventral patterning of the Drosophila embryo and for anterior-posterior (A/P) patterning of the wing imaginal disc. In the larval wing pouch, the Dpp target gene optomotor-blind (omb) is generally assumed to be expressed in a step function above a certain threshold of Dpp signaling activity. Results We show that the transcription factor Omb forms, in fact, a symmetrical gradient on both sides of the A/P compartment boundary. Disruptions of the Omb gradient lead to a re-organization of the epithelial cytoskeleton and to a retraction of cells toward the basal membrane suggesting that the O…
Conservatism and novelty in the genetic architecture of adaptation in Heliconius butterflies.
2015
Understanding the genetic architecture of adaptive traits has been at the centre of modern evolutionary biology since Fisher; however, evaluating how the genetic architecture of ecologically important traits influences their diversification has been hampered by the scarcity of empirical data. Now, high-throughput genomics facilitates the detailed exploration of variation in the genome-to-phenotype map among closely related taxa. Here, we investigate the evolution of wing pattern diversity in Heliconius, a clade of neotropical butterflies that have undergone an adaptive radiation for wing-pattern mimicry and are influenced by distinct selection regimes. Using crosses between natural wing-pat…
Sarcopenia and health-related outcomes: an umbrella review of observational studies
2019
Key summary pointsAimTo investigate associations of sarcopenia with adverse health-related outcomes, through an umbrella review method.FindingsSarcopenia appears to be significantly associated with several adverse outcomes in older people, with a strong evidence for increased risk of mortality, disability, and falls.MessageSarcopenia is associated with several adverse health-related outcomes in older people, indicating the need of assessing this condition in daily practice. AbstractBackgroundThe clinical relevance of sarcopenia has increasingly been recognized. However, whether it is associated with the development of other medical conditions is still unclear. Therefore, we aimed to capture…
Il Gran Caffè di Giuseppe Damiani Almeyda
2015
Il testo affronta lo studio di un’opera giovanile di Giuseppe Damiani Almeyda (1834-1911), figura di spicco del panorama architettonico in Sicilia tra la seconda metà dell’Ottocento ed i primi del Novecento. Il progetto del Gran Caffè, vincitore di prestigiosi riconoscimenti, anche se realizzato quando Damiani non era ancora trentenne, risulta molto maturo e segna una tappa importante nella formazione dell’architetto. Se ne ritroveranno richiami progettuali nel Politeama, edificio a cui il suo nome è legato, e in una grandiosa opera didattica, la Scuola Italiana di Architettura Civile, che, purtroppo, non è mai stata pubblicata. I disegni originali, a matita, inchiostro ed acquerello su car…
The mesothoracic wings of Afrotropical Scutelleridae (Hemiptera: Heteroptera): morphology and taxonomic significance
2013
Mesothoracic wings have been examined and compared in 32 species representing 20 genera of Afrotropical Scutelleri- dae. Morphological characters of the corium are described. Three main types of mesothoracic wing venation patterns can be recognized. The taxonomic significance of forewi ng characters in Scutelleridae is briefly discussed.
Martial Raysse, Dessins/Drawings
2015
International audience; Nouveau Réaliste en France, ami proche des artistes du pop art à New York et Los Angeles, réalisateur de films psychédéliques dans les communautés hippies au Maroc et ailleurs... Martial Raysse est l’un des artistes majeurs de la scène contemporaine. Alors que ses portraits de femmes ultracolorés des années 1960 sont devenus des icônes et que ses fresques allégoriques surprennent encore, les Éditions Dilecta publient un ouvrage présentant une sélection de ses dessins, de ses débuts à nos jours. Encore peu connues, ces œuvres sur papier sont empreintes de la même audace et impertinence que ses peintures, auréolées d’érotisme et de mythologies actualisées. Une centaine…
The Dorsocross T-box transcription factors promote tissue morphogenesis in the Drosophila wing imaginal disc.
2012
The Drosophila wing imaginal disc is subdivided into notum, hinge and blade territories during the third larval instar by formation of several deep apical folds. The molecular mechanisms of these subdivisions and the subsequent initiation of morphogenic processes during metamorphosis are poorly understood. Here, we demonstrate that the Dorsocross (Doc) T-box genes promote the progression of epithelial folds that not only separate the hinge and blade regions of the wing disc but also contribute to metamorphic development by changing cell shapes and bending the wing disc. We found that Doc expression was restricted by two inhibitors, Vestigial and Homothorax, leading to two narrow Doc stripes…
De piedra negra, tinta aguada y albayalde. Las técnicas de dibujo de Joan de Joanes y el 'estado del arte' en la Valencia del siglo XVI. ¿Tradición o…
2020
[ES] El presente artículo pretende realizar un somero análisis al corpus de dibujos sobre papel atribuido a Joan de Joanes y a sus más directos seguidores, desde una óptica metaformal, adentrándose en la génesis misma de tales diseños, desde su concepción hasta sus funciones. Han sido muy eventuales las apreciaciones sobre los procedimientos gráficos usados por el pintor y, en general, la cuestión de sus dibujos se ha abordado siempre desde la tradicional perspectiva de confrontación iconográfica y formal. No se ha ahondado en cuestiones que, a nuestro parecer, resultan claves para entender una figura tan poliédrica y compleja como la del artista valentino: como cuánto débito existe entre e…