Search results for "World health"

Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

2020

Abstract Background Tocilizumab is an IL-6 receptor-blocking agent proposed for the treatment of severe COVID-19. The aim of this systematic review was to describe the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy and safety. Methods MEDLINE, PubMed, EMBASE, pre-print repositories (bioRxiv and medRxiv) and two trial Registries were searched for studies on the use of tocilizumab in COVID-19 or SARS-CoV-2 infection, viral pneumonia, and/or sepsis until 20th June 2020. Results We identified 3 indirect pre-clinical studies and 28 clinical studies including 5776 patients with COVID-19 (13 with a comparison group,…

Smoking trends among adolescents from 1990 to 2002 in ten European countries and Canada.

2006

Abstract Background Daily smoking adolescents are a public health problem as they are more likely to become adult smokers and to develop smoking-related health problems later on in their lives. Methods The study is part of the four-yearly, cross-national Health Behaviour in School-aged Children study, a school-based survey on a nationally representative sample using a standardised methodology. Data of 4 survey periods are available (1990–2002). Gender-specific daily smoking trends among 14–15 year olds are examined using logistic regressions. Sex ratios are calculated for each survey period and country. Interaction effects between period and gender are examined. Results Daily smoking preval…

Crónica de una pandemia: confinamiento en Castelló de la Plana, España

2021

Este artículo presenta los resultados de una investigación comenzada a raíz de la declaración del estado de alarma en España (Real Decreto [RD] No. 463/2020, de 14 de marzo) después que la Organización Mundial de la Salud (OMS) declarase la enfermedad por coronavirus 2019 (COVID-19) como pandemia el día 11 de marzo de 2020. Este decreto limitaba la libre circulación de las personas, así como el derecho de reunión, tanto en lugares públicos como privados, además de imponer la obligatoriedad de mantener una distancia de seguridad entre los individuos y la limitación del aforo en aquellos establecimientos que permanecían abiertos, entre otras medidas. Todo ello supuso un cambioen las rutinas d…

Reflexiones sobre cómo evaluar y mejorar la respuesta a la pandemia de COVID-19

2020

La pandemia de COVID-19 ha afectado de manera particularmente intensa a España, pese a su nivel de desarrollo y la elogiada solidez de su Sistema Nacional de Salud. Para comprender qué ha pasado e identificar cómo mejorar la respuesta creemos imprescindible una evaluación independiente multidisciplinaria de la esfera sanitaria, política y socioeconómica. En este trabajo proponemos objetivos, principios, metodología y dimensiones a evaluar, además de esbozar el tipo de resultados y conclusiones esperadas. Nos inspiramos en los requerimientos formulados por el panel independiente de la Organización Mundial de la Salud y en las experiencias evaluativas en otros países, y detallamos la propuest…

Treating equivalent cases differently: A comparative analysis of substance use disorder and type 2 diabetes in Norwegian treatment guidelines

2022

Background Substance use disorder (SUD) is often understood as a chronic illness. Aims: This paper investigates whether SUD is treated as a chronic illness. Method To this aim, we have used World Health Organizations (WHO's) definition of chronic illness to conduct a comparative analysis of SUD and type 2 diabetes (T2D), which is another chronic illness. Results When analysing Norwegian treatment guidelines, we found that only the T2D guideline reflects the WHO's conceptualization of chronic illnesses. We argue that this discrepancy implies that SUD is understood as a moral and legal problem, while T2D is conceptualized as a somatic illness. We discuss how social, political and historical c…

La « mise en jeu » de la santé par la mondialisation

2003

A travers de nombreux exemples, Jean-Claude Fritz illustre le paradoxe auquel le monde se trouve aujourd’hui confronte : une richesse et un niveau de developpement sans precedent dans l’histoire, auxquels s’opposent aggravation des inegalites, violences, degradation de l’environnement... qui marginalisent une partie de l’humanite. Le changement est non seulement necessaire mais possible.

Carga global, regional y nacional de neurológicas. Desórdenes, 1990-2016: un análisis sistemático para el Global Estudio de la carga de enfermedad 20…

2019

Publisher´s version (útgefin grein).

Curbing tobacco's toll starts with the professionals: World No Tobacco Day

2005

The Eradication of Poliomyelitis in Spain: Projects, Obstacles, Achievements, Realities

2015

he main aim of our paper is to provide a historical approach to the complex process undertaken in Spain to achieve the official WHO certificate of polio eradication in 2002, within the framework of the initiatives launched in the WHO European Region. At the time of the first meeting of the European Regional Commission for the Certification of Poliomyelitis Eradication in 1996, the epidemiological situation and levels of vaccination cover (over 90%) enabled Spain, like other countries, to ensure compliance with the conditions set by the World Health Organization. This showed that the country, at the end of the twentieth century, had achieved high public health standards, which is remarkable …

Comparing analytical methods to detect SARS-CoV-2 in wastewater

2021

Wastewater based epidemiology (WBE) has emerged as a reliable strategy to assess the coronavirus disease 2019 (COVID-19) pandemic. Recent publications suggest that SARS-CoV-2 detection in wastewater is technically feasible; however, many different protocols are available and most of the methods applied have not been properly validated. To this end, different procedures to concentrate and extract inactivated SARS-CoV-2 and surrogates were initially evaluated. Urban wastewater seeded with gamma-irradiated SARS-CoV-2, porcine epidemic diarrhea virus (PEDV), and mengovirus (MgV) was used to test the concentration efficiency of an aluminum-based adsorption-precipitation method and a polyethylene…