Search results for "Wound"

showing 10 items of 534 documents

Long-term follow-up (42 months) of chronic anal fissure after healing with botulinum toxin.

2002

Abstract Background & Aims: Botulinum toxin is an effective treatment in idiopathic chronic anal fissure, but the long-term outcome after healing is not well documented. We analyzed the long-term outcome of patients in whom an anal fissure had healed after botulinum toxin injection and the factors contributing to recurrence. Methods: Fifty-seven patients who had completely healed 6 months after injection of botulinum toxin were reassessed every 6 months. The follow-up was 42 months in all patients. Clinical and manometric differences between the permanently healed and the relapsed group were statistically analyzed. Results: Four patients were lost to follow-up. A fissure recurrence was show…

AdultMalemedicine.medical_specialtyBotulinum ToxinsLong term follow upmedicine.medical_treatmentChronic anal fissureInjectionsRecurrenceLate RecurrencemedicinePressureEffective treatmentHumansAgedAnal fissureChemotherapyWound HealingHepatologyDose-Response Relationship Drugbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseBotulinum toxinSurgeryTotal doseChronic DiseaseRetreatmentFemaleFissure in Anobusinessmedicine.drugFollow-Up StudiesGastroenterology
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Improvement of wound healing after hemorrhoidectomy: a double-blind, randomized study of botulinum toxin injection.

2005

PURPOSE: Hemorrhoidectomy is usually associated with significant pain during the postoperative period. The spasm of the internal sphincter seems to play in important role in the origin of pain. This study was designed to evaluate the effectiveness of intrasphincter injection of botulinum toxin after hemaorrhoidectomy in reducing the maximum testing pressure of the anal canal, accelerating wound healing, and decreasing postoperative pain when resting and during defecation. METHODS: Thirty patients with hemorrhoids of third and fourth degree were included in the study and randomized in two groups. Anorectal manometry was performed preoperatively and 5 and 30 days afterward ill all patients un…

AdultMalemedicine.medical_specialtyBotulinum ToxinsManometrymedicine.medical_treatmentAnal CanalPainSodium ChlorideHemorrhoidsInternal anal sphincterHemorrhoidsDouble-Blind MethodPressureMedicineHumansbotulinum toxinDefecationSalineWound Healingposthemorrhoidectomy painbusiness.industryAnti-Dyskinesia AgentshemorrhoidectomyUrethral sphincterAnorectal manometryGastroenterologyGeneral MedicineAnal canalMiddle Agedmedicine.diseaseBotulinum toxinSurgerymedicine.anatomical_structureTreatment OutcomeAnesthesiaDefecationFemalebusinessmedicine.drugDiseases of the colon and rectum
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Symptomatic Deep Femoral Artery Pseudoaneurysm Endovascular Exclusion. Case Report and Literature Review.

2017

Deep femoral artery pseudoaneurysms (DFAPs) are rare and generally occur after penetrating trauma or surgical procedures. A 36-year-old obese man presented with pain in correspondence of the anterior-lateral thigh after 6 months from gunshot wound. Duplex and computed tomography (CT) showed a bilobed right DFAP (maximal diameter 12.9 cm). The patient was managed urgently, under local anesthesia, by placement in the distal DFA of a Viabahn 8 × 100-mm stent graft (W L Gore & Associates, Inc). The postoperative course was uneventful, and the 24-month CT showed regular stent-graft patency and 20-mm DFAP shrinkage. The literature review reported 8 cases of DFAPs; of these 6 were managed by endo…

AdultMalemedicine.medical_specialtyComputed Tomography Angiographymedicine.medical_treatment030204 cardiovascular system & hematologySettore MED/22 - Chirurgia Vascolare030218 nuclear medicine & medical imaging03 medical and health sciencesPseudoaneurysmBlood Vessel Prosthesis Implantation0302 clinical medicineAneurysmBlood vessel prosthesisDeep Femoral ArteryMedicineVascular PatencyHumansVascular PatencyUltrasonography Doppler Duplexbusiness.industryEndovascular ProceduresStentGeneral Medicinemedicine.diseaseSurgeryBlood Vessel ProsthesisFemoral Arterysurgical procedures operativeTreatment OutcomeRegional Blood FlowSurgeryStentsWounds GunshotRadiologyGunshot woundbusinessCardiology and Cardiovascular MedicinePenetrating traumaAneurysm FalseAnnals of vascular surgery
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Block iliac bone grafting enhances osseous healing of alveolar reconstruction in older cleft patients: A radiological and histological evaluation

2018

Background Older alveolar cleft patients (&12 years old) often have wide bone defect as well as teeth loss, resulting in poor osseous healing with conventional alveolar bone grafting (ABG). In this study, we investigated a surgical technique of block iliac bone grafting for the alveolar cleft reconstruction and evaluated the clinical and radiological outcomes of these cleft patients. Material and Methods Fifteen patients were included in this study. All cases received preoperative cone bean computed tomography (CBCT) scans for the alveolar cleft evaluation. Osseous outcomes of block iliac bone grafting were assessed at 1 week, 3- and 6-month postoperatively. Volume changes and bone resorpti…

AdultMalemedicine.medical_specialtyCone beam computed tomographyMature BoneAdolescentRadiographySurgical WoundPhysical examinationBone resorptionIliumYoung Adult03 medical and health sciences0302 clinical medicineTrabeculaAlveolar ProcessRadiography DentalmedicineHumansGeneral DentistryWound Healingmedicine.diagnostic_testbusiness.industryResearchAlveolar processAge FactorsSurgical wound030206 dentistryCone-Beam Computed Tomography:CIENCIAS MÉDICAS [UNESCO]SurgeryCleft PalateTreatment Outcomemedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASFemaleSurgeryOral SurgerybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Simple endoscopic decompression of cubital tunnel syndrome with the Agee system: anatomic study and first clinical results.

2010

BACKGROUND Simple decompression in ulnar nerve compression syndromes offers options for endoscopic applications. OBJECTIVE The authors present their initial experience with the Agee device. PATIENTS AND METHODS The monoportal endoscopic technique (Agee system) was evaluated on 10 cadaveric arms. Subsequently, 32 arms of 29 patients were operated on between January 2006 and March 2009. All patients presented with typical clinical signs and neurophysiologic studies. Long-term follow-up examinations were obtained in 27 of 32 arms. RESULTS In the cadaver study, the ulnar nerve was always correctly identified. No nerve damage occurred, and sufficient decompression of the ulnar nerve was always a…

AdultMalemedicine.medical_specialtyDecompressionCubital Tunnel SyndromePostoperative ComplicationsCadaverPreoperative CaremedicineCadaverElbowHumansUlnar nerve entrapmentUlnar nerveProspective cohort studyUlnar NerveAgedmedicine.diagnostic_testbusiness.industryDissectionSurgical woundEndoscopyMiddle Agedmedicine.diseaseDecompression SurgicalSurgeryEndoscopyTreatment OutcomePatient SatisfactionSurgeryFemaleNeurology (clinical)Cadaveric spasmbusinessNeurosurgery
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Surgery during etanercept therapy in patients with rheumatoid arthritis: is it time to follow patient preferences?

2008

Tumor necrosis factor (TNF)-a inhibitors, such as etanercept and infliximab, improve symptoms and function in patients affected by rheumatoid arthritis (RA) [1, 2] and, therefore, are playing an increasing role in the management of this disease. However, interference with endogenous TNF-a signalling has been reported to alter both normal inflammatory responses in tissue healing and infection surveillance [2, 3]. To our knowledge, the rates of surgery in RA are decreasing. However, with the duration of antiTNF therapy, the number of patients under these agents having surgery will be increasing. These data raise the question of whether TNF-inhibitors can be safely used in RA patients who shou…

AdultMalemedicine.medical_specialtyDiseaseReceptors Tumor Necrosis FactorEtanerceptEtanerceptArthritis RheumatoidPostoperative ComplicationsInternal MedicinemedicineOutpatient clinicHumansElective surgeryWound Healingbusiness.industryContraindicationsAnti-Inflammatory Agents Non-SteroidalMiddle Agedmedicine.diseaseInfliximabSurgeryItalyPatient SatisfactionRheumatoid arthritisImmunoglobulin GSurgical Procedures OperativeCohortEmergency MedicineQuality of LifeMethotrexateFemalebusinessmedicine.drugInternal and emergency medicine
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New mesh shape and improved implantation procedure to simplify and standardize open ventral hernia repair: a preliminary report.

2010

Introduction Issues in ventral hernia repair are represented by the need for mesh fixation and how to assure a sufficient mesh overlap of the defect. Aiming to resolve these problems, this study describes a modified technique for ventral and incisional hernia repair based upon a newly developed mesh with a special design. This new type of implant allows broader coverage of the abdominal wall and results in tension- and fixation-free repair. Materials and methods A unique geometrically shaped mesh consisting of a large central body and radiating arms was used to repair ventral or incisional hernia. The mesh was intended not to be point-fixated. The friction of the straps passing through the …

AdultMalemedicine.medical_specialtyHerniaFrictionIncisional herniaAbdominal wallProsthesis ImplantationHematomaPreliminary reportProstheseRecurrencemedicineHumansSurgical Wound InfectionHerniaHerniorrhaphyFixation (histology)AgedSurgical fixation deviceVentral hernia repairbusiness.industryAbdominal WallImplantMiddle AgedSurgical Meshmedicine.diseaseHernia VentralSurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureSeromaVentralSurgeryFemaleImplantbusinessFollow-Up StudiesHernia : the journal of hernias and abdominal wall surgery
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Seasonal variations in the onset and healing rates of venous leg ulcers

2010

Objectives As many vascular pathologies exhibit circannual fluctuation, the aim of this study was to assess the chronobiological features of venous ulcers. Methods Based on a retrospective survey of the case histories of 391 venous ulcer patients, the rates of ulcer onset and healing in each month were analysed statistically; a time series was constructed to evaluate the seasonality. Results There was a significantly higher frequency of ulcer onset during the warmer part of the year (April–October), and onset showed strong seasonality. Healing rates were also unequally and statistically significantly distributed throughout the year: ulcers that appeared or that were treated with specialized…

AdultMalemedicine.medical_specialtyHot TemperatureExacerbationChronic venous insufficiencyModels BiologicalGastroenterologyVaricose UlcerIschemiaRetrospective surveyInternal medicineleg ulcervenous insufficiencymedicineHumansAgedRetrospective StudiesAged 80 and overLegWound Healingbusiness.industryseasonal variationsRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseSurgeryChemotaxis LeukocyteLeg ulcerFemalePolandSeasonsCardiology and Cardiovascular MedicinebusinessPhlebology: The Journal of Venous Disease
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Plasma PCSK9 is a late biomarker of severity in patients with severe trauma injury.

2013

PCSK9 (proprotein convertase subtilisin kexin type 9) is a secreted protease that modulates cholesterol homeostasis by decreasing low-density lipoprotein receptor expression. Low levels of plasma lipoproteins are related to severity of illness and survival in patients of intensive care units (ICU).The aim of the study was to investigate the regulation of plasma PCSK9 and its association with plasma lipid parameters and clinical markers of severity during critical illness.The plasma biobank from the previously published HYPOLYTE prospective study was used to measure PCSK9 concentrations by ELISA at days 0 and 8 in 111 patients admitted to surgical ICU for severe multiple trauma. Patients wer…

AdultMalemedicine.medical_specialtyHydrocortisoneEndocrinology Diabetes and MetabolismReceptor expressionCritical IllnessClinical BiochemistryContext (language use)PlaceboBiochemistryGastroenterologySeverity of Illness IndexPlacebosEndocrinologyIntensive careInternal medicineSeverity of illnessmedicineHumansProspective cohort studyInfusion PumpsHydrocortisoneTrauma Severity Indicesbusiness.industryPCSK9Biochemistry (medical)Serine EndopeptidasesCholesterol LDLPrognosisIntensive Care UnitsEndocrinologyImmunologyWounds and InjuriesFemaleProprotein ConvertasesProprotein Convertase 9businessBiomarkersmedicine.drugThe Journal of clinical endocrinology and metabolism
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Use of buccal fat pad to repair post-extraction peri-implant bone defects in the posterior maxilla: a preliminary prospective study

2015

Background: Extensive literature exists about the use of the BFP in the treatment of oral defects but, to our knowledge, no article refers to the use of the BFP as a substitute of the membrane barriers for treatment of peri- implant bone defects. The aim was to evaluate the use of the buccal fat pad as a coating material for bone grafting in the peri-implant bone defect regeneration of immediate implants placed in the posterior maxilla. Material and Methods: A preliminary prospective study of patients involving immediate implants in which the buccal fat pad was used as a coating material to peri-implant bone defects was carried out. The outcome measures assessed were: postoperative pain and…

AdultMalemedicine.medical_specialtyImmediate Dental Implant Loadingmedicine.medical_treatmentAlveolar Bone LossDentistryOdontologíaBone graftingPeri implant bonemedicineHumansProspective StudiesProspective cohort studyGeneral DentistryAgedBuccal fat padBone Transplantationbusiness.industryWound dehiscenceResearchMean ageAlveolar Ridge AugmentationMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludSurgeryOtorhinolaryngologyAdipose TissueUNESCO::CIENCIAS MÉDICASSurgeryFemaleImplantOral SurgerybusinessPosterior maxilla
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