Search results for "X-fragile"

Anxiety levels in mothers of children affected by x-fragile syndrome

2017

Introduction: Anxiety is the psychological process by which the individual reacts to dangerous external stimuli, triggering responses (mediated by norepinephrine, GABA and serotonin) involving physiological reactions and cognitive strategies. Anxiety can be differentiated in state anxiety and trait anxiety. Fragile X Syndrome (FXS) is a disorder most commonly caused by a triplet repeat expansion of > 200 cytosine-guanine-guanine (CGG) repeats in the 50 untranslated region of the Fragile X mental retardation 1 (FMR1) gene. Aim of the present study is investigating the state or trait anxiety in a sample of mothers of children affected by X-fragile. Materials and methods: 84 mothers (mean age …