Search results for "X-rays."

showing 10 items of 443 documents

High speed X-ray analysis of plant enzymes at room temperature.

2013

X-ray measurements at room temperature (295 K) deliver high quality data sets with unprecedented speed (2 min), as shown for crystallized raucaffricine-O-β-D-glucosidase (RG), its mutant RG-Glu186Gln and several ligand complexes of the enzyme which participates in alkaloid biosynthesis in the plant Rauvolfia. The data obtained are compared with data sets measured under typical cryo conditions (100K). Under both conditions, density maps are highly comparable and favor the described protocol for room temperature measurements, potentially paving the way for future crystallographic studies capturing biosynthetic pathway intermediates.

chemistry.chemical_classificationModels MolecularRauvolfiabiologyLigandX-RaysMutantMolecular ConformationTemperaturePlant ScienceGeneral MedicineHorticulturebiology.organism_classificationBiochemistryTemperature measurementRauwolfiaCrystallographyEnzymeAlkaloidschemistryRauvolfia serpentinaHydrolaseX-ray crystallographyMolecular BiologyGlucosidasesPhytochemistry
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ElaC Encodes a Novel Binuclear Zinc Phosphodiesterase

2002

ElaC is a widespread gene found in eubacteria, archaebacteria, and mammals with a highly conserved sequence. Two human ElaC variants were recently associated with cancer (Tavtigian, S. V., Simard, J., Teng, D. H., Abtin, V., Baumgard, M., Beck, A., Camp, N. J., Carillo, A. R., Chen, Y., Dayananth, P., Desrochers, M., Dumont, M., Farnham, J. M., Frank, D., Frye, C., Ghaffari, S., Gupte, J. S., Hu, R., Iliev, D., Janecki, T., Kort, E. N., Laity, K. E., Leavitt, A., Leblanc, G., McArthur-Morrison, J., Pederson, A., Penn, B., Peterson, K. T., Reid, J. E., Richards, S., Schroeder, M., Smith, R., Snyder, S. C., Swedlund, B., Swensen, J., Thomas, A., Tranchant, M., Woodland, A. M., Labrie, F., Sko…

chemistry.chemical_elementZincBiologymedicine.disease_causeBiochemistrybeta-LactamasesHomology (biology)Conserved sequenceGene productEscherichia colimedicineHistidineCloning MolecularBinding siteMolecular BiologyEscherichia coliHistidineCell NucleusIonsBinding SitesModels StatisticalPhosphoric Diester HydrolasesSpectrum AnalysisX-RaysPhosphodiesteraseCell BiologyProtein Structure TertiaryOxygenKineticsZincBiochemistrychemistryChromatography GelProtonsDimerizationProtein BindingJournal of Biological Chemistry
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Direct Measurement of Mammographic X-Ray Spectra with a Digital CdTe Detection System

2012

In this work we present a detection system, based on a CdTe detector and an innovative digital pulse processing (DPP) system, for high-rate X-ray spectroscopy in mammography (1–30 keV). The DPP system performs a height and shape analysis of the detector pulses, sampled and digitized by a 14-bit, 100 MHz ADC. We show the results of the characterization of the detection system both at low and high photon counting rates by using monoenergetic X-ray sources and a nonclinical X-ray tube. The detection system exhibits excellent performance up to 830 kcps with an energy resolution of 4.5% FWHM at 22.1 keV. Direct measurements of clinical molybdenum X-ray spectra were carried out by using a pinhole…

digital pulse processingmammographyAnalytical chemistrylcsh:Chemical technologyBiochemistryArticleAnalytical ChemistryCdTe detectorsCdTe detectorOpticsmedicineCadmium CompoundsMammographylcsh:TP1-1185Computer SimulationElectrical and Electronic EngineeringInstrumentationPhysicsDosimetermedicine.diagnostic_testbusiness.industryAttenuationSpectrum AnalysisX-RaysDetectorSettore FIS/01 - Fisica Sperimentalehigh photon counting rateCdTe detectors Digital Pulse Processing MammographySignal Processing Computer-AssistedAtomic and Molecular Physics and OpticsPhoton countingSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Full width at half maximumX-ray spectroscopy; high photon counting rate; CdTe detectors; digital pulse processing; mammographyIonization chamberX-ray spectroscopyTelluriumbusinessHalf-value layerSensors; Volume 12; Issue 6; Pages: 8390-8404
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High-energy monitoring of NGC 4593 II. Broad-band spectral analysis: testing the two-corona model

2019

It is widely believed that the primary X-ray emission of AGN is due to the Comptonisation of optical-UV photons from a hot electron corona, while the origin of the 'soft-excess' is still uncertain and matter of debate. A second Comptonisation component, called warm corona, was therefore proposed to account for the soft-excess, and found in agreement with the optical-UV to X-ray emission of a sample of Seyfert galaxies. In this context, we exploit the broadband XMM-Newton and NuSTAR simultaneous observations of the Seyfert galaxy NGC 4593 to further test the so called "two corona model". The NGC 4593 spectra are well reproduced by the model, from the optical/UV to the hard X-rays. Moreover, …

galaxie [X-rays]High energyPhotonAstrophysics::High Energy Astrophysical Phenomenablack hole physicsgalaxies: activeFOS: Physical sciencesContext (language use)AstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesmagnetohydrodynamics (MHD)Spectral lineCorona (optical phenomenon)X-rays: binariesaccretionPrimary (astronomy)Seyfert [galaxies]0103 physical sciencesAstrophysics::Solar and Stellar AstrophysicsSpectral analysis010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)individuals: (NGC 4593) [X-rays][SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph]010308 nuclear & particles physicsaccretion disks[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]Astronomy and AstrophysicsAstronomy and AstrophysicGalaxygalaxies: SeyfertX-rays: galaxiesISM: jets and outflowsSpace and Planetary Science[SDU]Sciences of the Universe [physics]active [galaxies]Astrophysics - High Energy Astrophysical Phenomena[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]X-rays: individuals: (NGC 4593)
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Testing warm Comptonization models for the origin of the soft X-ray excess in AGNs

2018

The X-ray spectra of many active galactic nuclei (AGN) show a soft X-ray excess below 1-2 keV on top of the extrapolated high- energy power law. The origin of this component is uncertain. It could be a signature of relativistically blurred, ionized reflection, or the high-energy tail of thermal Comptonization in a warm (kT $\sim$ 1 keV), optically thick ($\tau\simeq$ 10-20) corona producing the optical/UV to soft X-ray emission. The purpose of the present paper is to test the warm corona model on a statistically significant sample of unabsorbed, radio-quiet AGN with XMM-newton archival data, providing simultaneous optical/UV and X-ray coverage. The sample has 22 objects and 100 observations…

galaxie [X-rays]Seyfert [Galaxies]Active galactic nucleusactive [Galaxies][ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]Astrophysics::High Energy Astrophysical Phenomenagalaxies: activeFOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics7. Clean energy01 natural sciencesPower lawSpectral lineAccretion discIonization0103 physical sciencesThermalAstrophysics::Solar and Stellar Astrophysics010303 astronomy & astrophysicsAstrophysics::Galaxy AstrophysicsPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Soft x ray010308 nuclear & particles physicsAstronomy and AstrophysicsAstronomy and AstrophysicGalaxygalaxies: SeyfertX-rays: galaxiesSpace and Planetary Science[SDU]Sciences of the Universe [physics]Astrophysics - High Energy Astrophysical Phenomena[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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The XMM Cluster Outskirts Project (X-COP): Thermodynamic properties of the Intracluster Medium out to $R_{200}$ in Abell 2319

2018

We present the joint analysis of the X-ray and SZ signals in A2319, the galaxy cluster with the highest signal-to-noise ratio in Planck maps and that has been surveyed within our XMM Cluster Outskirts Project (X-COP). We recover the thermodynamical profiles by the geometrical deprojection of the X-ray surface brightness, of the SZ comptonization parameter, and an accurate and robust spectroscopic measurements of the temperature. We resolve the clumpiness of the density to be below 20 per cent demonstrating that most of this clumpiness originates from the ongoing merger and can be associated to large-scale inhomogeneities. This analysis is done in azimuthally averaged radial bins and in eigh…

galaxies: clusters: general ; galaxies: clusters: intracluster medium – X-rays; galaxies: clusters – intergalactic mediumgalaxies: clusters: intracluster medium – X-raysCosmology and Nongalactic Astrophysics (astro-ph.CO)galaxies: clusters: intracluster medium[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]FOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural scienceslaw.inventionlawIntracluster medium0103 physical sciencesROSATCluster (physics)Surface brightnessTotal pressure010303 astronomy & astrophysicsGalaxy clusterComputingMilieux_MISCELLANEOUSAstrophysics::Galaxy AstrophysicsPhysicsgalaxies: clusters – intergalactic medium[SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph]010308 nuclear & particles physicsSettore FIS/05Astronomy and AstrophysicsAstronomy and AstrophysicX-rays: galaxies: clusterGalaxySpace and Planetary Sciencegalaxies: clusters: generalX-rays: galaxies: clustersintergalactic mediumHydrostatic equilibrium[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Astrophysics - Cosmology and Nongalactic Astrophysics
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Mass-Metallicity Relation from Cosmological Hydrodynamical Simulations and X-ray Observations of Galaxy Groups and Clusters

2018

Recent X-ray observations of galaxy clusters show that the distribution of intra-cluster medium (ICM) metallicity is remarkably uniform in space and time. In this paper, we analyse a large sample of simulated objects, from poor groups to rich clusters, to study the dependence of the metallicity and related quantities on the mass of the systems. The simulations are performed with an improved version of the Smoothed-Particle-Hydrodynamics \texttt{GADGET-3} code and consider various astrophysical processes including radiative cooling, metal enrichment and feedback from stars and active galactic nuclei (AGN). The scaling between the metallicity and the temperature obtained in the simulations ag…

galaxies: clusters: intracluster mediumActive galactic nucleusCosmology and Nongalactic Astrophysics (astro-ph.CO)MetallicityFOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesmethods: numericalGalaxy groups and clusters0103 physical sciencesCluster (physics)clusters: general [galaxies]methods: numerical; galaxies: clusters: general; galaxies: clusters: intracluster medium; X-rays: galaxies: clusters010303 astronomy & astrophysicsScalingGalaxy clusterPhysics010308 nuclear & particles physicsnumerical [methods]Astronomy and AstrophysicsAstrophysics - Astrophysics of GalaxiesRedshiftStarsgalaxies: clusters: generalclusters: intracluster medium [galaxies]Space and Planetary ScienceX-rays: galaxies: clustersAstrophysics of Galaxies (astro-ph.GA)galaxies: clusters [X-rays]Astrophysics - Cosmology and Nongalactic Astrophysics
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Cosmological hydrodynamical simulations of galaxy clusters: X-ray scaling relations and their evolution

2018

We analyse cosmological hydrodynamical simulations of galaxy clusters to study the X-ray scaling relations between total masses and observable quantities such as X-ray luminosity, gas mass, X-ray temperature, and $Y_{X}$. Three sets of simulations are performed with an improved version of the smoothed particle hydrodynamics GADGET-3 code. These consider the following: non-radiative gas, star formation and stellar feedback, and the addition of feedback by active galactic nuclei (AGN). We select clusters with $M_{500} > 10^{14} M_{\odot} E(z)^{-1}$, mimicking the typical selection of Sunyaev-Zeldovich samples. This permits to have a mass range large enough to enable robust fitting of the r…

galaxies: clusters: intracluster mediumCosmology and Nongalactic Astrophysics (astro-ph.CO)Active galactic nucleusNUMERICAL [METHODS]Ciencias FísicasFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysicsnumerical galaxies: clusters: general galaxies: clusters: intracluster medium X-rays: galaxies: clusters [methods]01 natural sciencesmethods: numericalLuminosity//purl.org/becyt/ford/1 [https]GALAXIES: CLUSTERS [X-RAYS]Smoothed-particle hydrodynamics0103 physical sciences010303 astronomy & astrophysicsScalingAstrophysics::Galaxy AstrophysicsGalaxy clusterPhysicsmethods: numerical galaxies: clusters: general galaxies: clusters: intracluster medium X-rays: galaxies: clustersSettore FIS/05010308 nuclear & particles physicsStar formationAstronomy and AstrophysicsObservable//purl.org/becyt/ford/1.3 [https]RedshiftAstronomíamethods: numerical; galaxies: clusters: general; galaxies: clusters: intracluster medium; X-rays: galaxies: clusters; Astrophysics - Cosmology and Nongalactic Astrophysicsgalaxies: clusters: generalSpace and Planetary ScienceX-rays: galaxies: clustersCLUSTERS: INTRACLUSTER MEDIUM [GALAXIES]CLUSTERS: GENERAL [GALAXIES]CIENCIAS NATURALES Y EXACTASAstrophysics - Cosmology and Nongalactic AstrophysicsMonthly Notices of the Royal Astronomical Society
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Non-thermal pressure support in X-COP galaxy clusters

2018

Galaxy clusters are the endpoints of structure formation and are continuously growing through the merging and accretion of smaller structures. Numerical simulations predict that a fraction of their energy content is not yet thermalized, mainly in the form of kinetic motions (turbulence, bulk motions). Measuring the level of non-thermal pressure support is necessary to understand the processes leading to the virialization of the gas within the potential well of the main halo and to calibrate the biases in hydrostatic mass estimates. We present high-quality measurements of hydrostatic masses and intracluster gas fraction out to the virial radius for a sample of 12 nearby clusters with availab…

galaxies: clusters: intracluster mediumStructure formationCosmology and Nongalactic Astrophysics (astro-ph.CO)[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]Cosmic microwave backgroundFOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic Astrophysics01 natural sciencesVirial theoremCosmologylaw.inventionsymbols.namesakelaw0103 physical sciencesPlanck010303 astronomy & astrophysicsGalaxy clusterAstrophysics::Galaxy AstrophysicsPhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)[SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph]Settore FIS/05010308 nuclear & particles physicsComputer Science::Information RetrievalAstronomy and AstrophysicsAstrophysics - Astrophysics of GalaxiesX-rays: galaxies: clusters; large-scale structure of Universe; galaxies: clusters: intracluster medium; galaxies: clusters: generalgalaxies: clusters: generalSpace and Planetary ScienceX-rays: galaxies: clustersAstrophysics of Galaxies (astro-ph.GA)symbolslarge-scale structure of UniverseHaloHydrostatic equilibriumAstrophysics - High Energy Astrophysical Phenomena[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]X-rays: galaxies: clusters - Galaxies: clusters: general - Galaxies: groups: general - Galaxies: clusters: intracluster medium - cosmology: large-scale structureAstrophysics - Cosmology and Nongalactic Astrophysics
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X-ray and optical emission in protostellar jets: model predictions and comparison with observations

2007

hydrodynamics – Herbig-Haro objects – ISM: jets and outflows – X-rays: ISM
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