Search results for "XY"

showing 10 items of 13736 documents

CCDC 1455868: Experimental Crystal Structure Determination

2016

Related Article: Philipp Benrath, Maximilian Kaiser, Thomas Limbach, Mihail Mondeshki and Jan Klett|2016|Angew.Chem.,Int.Ed.|55|10886|doi:10.1002/anie.201602792

pentakis(mu-t-butoxy)-tris(mu-neopentyl)-tetra-lithium-tetra-potassiumSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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In Vitro Cytotoxic Effect of Aqueous Extracts from Leaves and Rhizomes of the Seagrass Posidonia oceanica (L.) Delile on HepG2 Liver Cancer Cells: Fo…

2023

Aqueous extracts from Posidonia oceanica’s green and brown (beached) leaves and rhizomes were prepared, submitted to phenolic compound and proteomic analysis, and examined for their potential cytotoxic effect on HepG2 liver cancer cells in culture. The chosen endpoints related to survival and death were cell viability and locomotory behavior, cell-cycle analysis, apoptosis and autophagy, mitochondrial membrane polarization, and cell redox state. Here, we show that 24 h exposure to both green-leaf- and rhizome-derived extracts decreased tumor cell number in a dose–response manner, with a mean half maximal inhibitory concentration (IC50) estimated at 83 and 11.5 μg of dry extract/mL, respecti…

phenolic compoundreactive oxygen specieSettore CHIM/10 - Chimica Degli AlimentiGeneral Immunology and MicrobiologycaspaseSettore BIO/05 - Zoologiaproteomic analysiscell biology; cell cycle; reactive oxygen species; wound healing assay; caspases; mitochondrial transmembrane potential; clonogenic assay; phenolic compounds; proteomic analysisGeneral Biochemistry Genetics and Molecular Biologycell biologymitochondrial transmembrane potentialcell cycleclonogenic assaySettore BIO/06 - Anatomia Comparata E CitologiaGeneral Agricultural and Biological Scienceswound healing assayBiology
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Remarkable effect of organoaluminum activator on catalytic performance of bis(phenoxy-imine) titanium complexes in ethylene polymerization

2009

Zsyntezowano i sprawdzono w polimeryzacji etylenu, po uprzedniej aktywacji zarówno MAO, jak i prostymi związkami glinoorganicznymi (Et3Al, Et2AlCl, EtAlCl2), trzy kompleksy tytanu z ligandami fenoksy-iminowymi: dichlorek bis[N-(3,5-di-tert-butylosalicylideno)anilino]tytanu(IV) (kompleks I), dichlorek bis[N-(3,5-di-tert-butylosalicylideno)-1-naftyloamino]tytanu(IV) (kompleks II) i dichlorek bis[N-(salicylideno)-1-naftyloamino]tytanu(IV) (kompleks III). Stwierdzono, że zarówno struktura ligandów, jak i rodzaj glinoorganicznego aktywatora mają wpływ na aktywność badanych kompleksów. Kompleks I, zawierający podstawnik fenylowy przy iminowym atomie azotu okazał się najaktywniejszy w połączeniu z…

phenoxy-imine ligandkatalizator FIpolimeryzacja etylenukatalizator postmetalocenowypost-metallocene catalystFI catalystligand fenoksy-iminowyethylene polymerizationPolimery
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Degradation of an alkaloid pheromone from the pale-brown chafer, Phyllopertha diversa (Coleoptera: Scarabaeidae), by an insect olfactory cytochrome P…

1999

AbstractThe pale-brown chafer, Phyllopertha diversa, utilizes an unusual alkaloid, 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione, as its sex pheromone. This compound is rapidly degraded in vitro by the antennal protein extracts from this scarab beetle. Demethylation at the N-1 position and hydroxylation of the aromatic ring have been identified as the major catabolic pathways. The enzyme responsible for the pheromone degradation is membrane-bound, requires NAD(P)H for activity and is sensitive to cytochrome P450 inhibitors, such as proadifen and metyrapone. The ability to metabolize this unusual pheromone was not detected in 12 species tested, indicating that the P450 system, specific to male P…

pheromone-degrading enzymemedia_common.quotation_subjectBiophysicsInsectOlfactionscarab beetleBiochemistryMass SpectrometryHydroxylationchemistry.chemical_compoundAlkaloidsCytochrome P-450 Enzyme SystemStructural BiologyMicrosomesBotanyGeneticsAnimalsCytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsSex AttractantsMolecular BiologyChromatography High Pressure LiquidDemethylationmedia_commonbiologyMolecular StructureProadifenCytochrome P450Cell BiologyMetyraponeProadifenColeopteraBiochemistrychemistrySex pheromonebiology.proteinQuinazolinesPheromoneInsect ProteinsChromatography Thin Layerpheromone inactivationolfactionFEBS letters
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Conformational-Dependent Photodissociation of Glycolic Acid in an Argon Matrix

2023

Ultraviolet-induced photodissociation and photo-isomerization of the three most stable conformers (SSC, GAC, and AAT) of glycolic acid are investigated in a low-temperature solid argon matrix using FTIR spectroscopy and employing laser radiation with wavelengths of 212 nm, 226 nm, and 230 nm. The present work broadens the wavelength range of photochemical studies of glycolic acid, thus extending the understanding of the overall photochemistry of the compound. The proposed kinetic model for the photodissociation of glycolic acid proceeds from the lowest energy conformer (SSC). The model suggests that ultraviolet light induces isomerization only between the SSC and GAC conformers and between …

photochemistrymatrix isolationGeneral Medicinedissociationreaktiomekanismithydroxy acidglycolic acidisomerizationvibrational spectroscopychemical kineticshajoaminen (kemia)reaction mechanismvalokemiaglycolic acid; hydroxy acid; dissociation; isomerization; chemical kinetics; reaction mechanism; matrix isolation; vibrational spectroscopy; photochemistryPhotochem
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Children in the visual coverage of the European refugee crisis: A case study of the World Press Photo 2016

2018

Shifts in the visual coverage of refugees arriving in Europe and prominent compassion fatigue emphasize the need to examine visual strategies utilized to report on the crisis. This study focuses on representations of refugee children using a case of the World Press Photo (WPP) 2016. The material was interpreted with a model for visual rhetorical interpretation of journalistic photographs. Findings indicate the main visual elements involved in representing refugee children: visual trope of the migrant father, relation between children and barriers, visual oxymoron (juxtaposition of contradictory elements) and atmosphere in photographs. Findings suggest that photographs address polemics speci…

photography interpretationHistorymedia_common.quotation_subjectRefugeeTrope (literature)child migrantcompassion fatigue050801 communication & media studiesCompassionWorld Press Photo 20160508 media and communicationsOxymoronRhetorical question0501 psychology and cognitive sciencesrefugeeta518lapsetvalokuvatvisual rhetoricmedia_commonkuvallinen viestintävisuaalisuusCommunicationInterpretation (philosophy)05 social sciencesGender studiesVisual rhetoricCompassion fatiguepakolaiset050104 developmental & child psychologyJournal of Applied Journalism & Media Studies
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Modulation of Efficient Diiodo-BODIPY in vitro Phototoxicity to Cancer Cells by Carbon Nano-Onions

2020

Photodynamic therapy (PDT) is currently one of the most promising approaches for targeted cancer treatment. It is based on responses of vital physiological signals, namely reactive oxygen species (ROS), which are associated with diseased condition development, such as tumors. This study presents the synthesis, incorporation, and application of a diiodo-BODIPY based photosensitizer, based on a non-covalent functionalization of carbon nano-onions (CNOs). In vitro assays demonstrate that HeLa cells internalize the diiodo-BODIPY molecules, and their CNOs nanohybrids. Upon cell internalization and light exposure, the pyrene-diiodo-BODIPY molecules induce an increase of the ROS level of HeLa cell…

photosensitizermedicine.medical_treatmentPhotodynamic therapy02 engineering and technology010402 general chemistry01 natural sciencesHeLalcsh:ChemistrymedicinePhotosensitizerCytotoxicitychemistry.chemical_classificationreactive oxygen speciesReactive oxygen speciesbiologyGeneral Chemistry021001 nanoscience & nanotechnologybiology.organism_classificationIn vitro0104 chemical scienceschemistryphotodynamic therapylcsh:QD1-999Settore CHIM/09 - Farmaceutico Tecnologico ApplicativoCancer cellBiophysicscancer treatments0210 nano-technologyPhototoxicitycarbon nano-onionsFrontiers in Chemistry
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Synthesis, characterization, and cellular investigations of porphyrin– and chlorin–indomethacin conjugates for photodynamic therapy of cancer

2021

Indomethacin is a potent non-steroidal anti-inflammatory drug (NSAID) with a strong selective inhibitor activity towards cyclooxygenase-2 (COX-2), an enzyme that is highly overexpressed in various tumour cells, being involved in tumourigenesis. Concomitantly, porphyrins have gained much attention as promising photosensitizers (PSs) for the non-invasive photodynamic therapy (PDT) of cancer. Herein, we report the design, and determine the singlet oxygen generation capacity and in vitro cellular toxicity of porphyrin- and chlorin-indomethacin conjugates (P2-Ind and C2-Ind). Both the conjugates were obtained in high yields and were characterized by 1H, 19F and 13C NMR as well as by high resolut…

photosensitizermedicine.medical_treatmentPhotodynamic therapyDFT calculations010402 general chemistryPhotochemistry01 natural sciencesBiochemistrychemistry.chemical_compoundnon-steroidal anti-inflammatory drugpolycyclic compoundsmedicinePhysical and Theoretical ChemistryTriplet stateCytotoxicity010405 organic chemistrySinglet oxygenOrganic Chemistrysinglet oxygen generationPorphyrin0104 chemical sciencesPhotochemotherapychemistrySettore CHIM/03 - Chimica Generale E InorganicaChlorincytotoxicityPhototoxicityporphyrinConjugateOrganic & Biomolecular Chemistry
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Editorial: Flavonoids: From Biosynthesis and Metabolism to Health Benefits

2021

descripción no proporcionada por scopus

pinostrobin pharmacokineticsCatechin galloylationPinostrobin pharmacokineticsanthocyanin contentcatechin galloylationFlavonoidVitexinHydroxysafflor Yellow APlant SciencePharmacologySB1-1110chemistry.chemical_compoundmedicineFormononetinVitexinisoflavonesAnthocyanin contentchemistry.chemical_classificationFormononetinXanthohumolPlant cultureMetabolismIsoflavonesIsoflavonesxanthohumolchemistryMechanism of actionPolyphenolhydroxysafflor Yellow AXanthohumolmedicine.symptomFrontiers in Plant Science
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A giant planet beyond the snow line in microlensing event OGLE-2011-BLG-0251

2013

We present the analysis of the gravitational microlensing event OGLE-2011-BLG-0251. This anomalous event was observed by several survey and follow-up collaborations conducting microlensing observations towards the Galactic Bulge. Based on detailed modelling of the observed light curve, we find that the lens is composed of two masses with a mass ratio q=1.9 x 10^-3. Thanks to our detection of higher-order effects on the light curve due to the Earth's orbital motion and the finite size of source, we are able to measure the mass and distance to the lens unambiguously. We find that the lens is made up of a planet of mass 0.53 +- 0.21,M_Jup orbiting an M dwarf host star with a mass of 0.26 +- 0.…

planets and satellites: detection010504 meteorology & atmospheric sciencesSatellitesbulge [Galaxy]FOS: Physical sciencesAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsDiscoveryGravitational microlensing01 natural sciencesGalaxy: bulgeEinstein radiusLensgravitational lensing: weakSettore FIS/05 - Astronomia e AstrofisicaPlanetSnow0103 physical sciencesgravitational lensing; weak; planets and satellites; detection; planetary systems; Galaxy; bulgegravitational lensing: weak; planets and satellites: detection; planetary systems; Galaxy: bulgeBinaryQB Astronomy010303 astronomy & astrophysicsplanetary systemsAstrophysics::Galaxy Astrophysics0105 earth and related environmental sciencesQBPhysicsEarth and Planetary Astrophysics (astro-ph.EP)Giant planetSystemsSearchAstronomy and AstrophysicsRadiusFrequencyPlanetary systemMass ratioMassLight curveStarsAlgorithmdetection [Planets and satellites]Planetary systemsSpace and Planetary ScienceDwarfAstrophysics::Earth and Planetary Astrophysicsweak [Gravitational lensing]Astrophysics - Earth and Planetary AstrophysicsAstronomy and Astrophysics
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