Search results for "YPO"

Proactive avoidance behaviour and pace-of-life syndrome in Atlantic salmon

2019

Individuals in a fish population differ in key life-history traits such as growth rate and body size. This raises the question of whether such traits cluster along a fast-slow growth continuum according to a pace-of-life syndrome (POLS). Fish species like salmonids may develop a bimodal size distribution, providing an opportunity to study the relationships between individual growth and behavioural responsiveness. Here we test whether proactive characteristics (bold behaviour coupled with low post-stress cortisol production) are related to fast growth and developmental rate in Atlantic salmon, Salmo salar . Boldness was tested in a highly controlled two-tank hypoxia test were oxygen levels …

Differences in Participation and Performance Trends in Age Group Half and Full Marathoners

2014

International audience; Recent studies investigated participation and performance trends in age group half marathoners and full marathoners for a single event. The present study investigated participation and performance trends in age group athletes in all half marathons and full marathons held in a single country during a given period of time. Changes in running performance and age of 226,754 half marathoners and 86,419 full marathoners competing in Switzerland between 2000 and 2010 were analyzed using linear regression analyses. The number of half marathoners increased (P < 0.01) from 2000 to 2010 for both men (+231%) and women (+299%). In contrast, the number of male and female full mara…

Diabète de type 2 chez le sujet âgé : quelles spécificités ?

2012

Type 2 diabetes, whose prevalence has increased among elderly aged over 75 years, has a number of specific features which differ from that in young people: heterogeneous population, association with other cardiovascular risk factors and several comorbidities, different therapeutic constraints and risks, and lower life expectancy. By using a standardized geriatric assessment it is possible to determine therapeutic and glycemic goals for each patient. In the elderly, main complications of diabetes are hypoglycemia and foot lesions. In order to avoid malnutrition, lifestyle and dietary rules should not be too strict. Recommendations for the prescription of oral antidiabetic agents are the same…

2019

Impact of leptospermone, a β-triketone bioherbicide, was investigated on the fungal community which supports important soil ecological functions such as decomposition of organic matter and nutrients recycling. This study was done in a microcosm experiment using two French soils, Perpignan (P) and Saint-Jean-de-Fos (SJF), differing in their physicochemical properties and history treatment with synthetic β-triketones. Soil microcosms were treated with leptospermone at recommended dose and incubated under controlled conditions for 45 days. Untreated microcosms were used as control. Illumina MiSeq sequencing of the internal transcribed spacer region of the fungal rRNA revealed significant chang…

The effect of bergamot on dyslipidemia

2016

Abstract Background Statins are the most common used lipid lowering drugs but they may cause adverse effects and despite their well-established therapeutic benefits residual cardiovascular (CV) risk remains. The use of other lipid lowering drugs and nutraceuticals alone or as add-on lipid-modifying therapy can be an option in such cases. Several studies have reported health-related properties of the Citrus fruits, among which bergamot (Citrus bergamia Risso) differs from others by particularly high content of certain compounds. Purpose This narrative review summarizes the current evidence on the effects of bergamot on lipid parameters based on studies involving animals and humans. Main evid…

Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents

2019

Type 2 diabetes mellitus (T2DM) is an important metabolic disorder for which there is an urgent need for new antidiabetic drugs. α-Glucosidase inhibition is an established protocol for T2DM therapy. Because hyperglycemia causes oxidative tissue damage, the development of agents with both α-glucosidase inhibition and antioxidant activity from natural or natural-derived polyphenols such derivatives of rosmarinic acid (RA) represents an attractive therapeutic option. We report a study on amides 1-10 derived from RA and their evaluation for yeast α-glucosidase inhibition and antioxidant activity (DPPH and ORAC tests). All amides showed higher inhibitory activity than that of RA, were by far mor…

3H-DA release evoked by low pH medium and internal H+ accumulation in rat hypothalamic synaptosomes

2002

Understanding the Significance of the Hypothalamic Nature of the Subthalamic Nucleus

2021

AbstractThe subthalamic nucleus (STN) is an essential component of the basal ganglia and has long been considered to be a part of the ventral thalamus. However, recent neurodevelopmental data indicated that this nucleus is of hypothalamic origin which is now commonly acknowledged. In this work, we aimed to verify whether the inclusion of the STN in the hypothalamus could influence the way we understand and conduct research on the organization of the whole ventral and posterior diencephalon. Developmental and neurochemical data indicate that the STN is part of a larger glutamatergic posterior hypothalamic region that includes the premammillary and mammillary nuclei. The main anatomic charact…

Sobre la vegetación de la alianza Homalothecio-Polypodion serrati en las montañas valencianas

1983

Se han estudiado las comunidades de la alianza Homalothecio-Polypodion serrati en las montañas de la región valenciana y alrededores, encontrándose que las mismas pueden atribuirse a cuatro asociaciones: Anomodonio-Polypodietum serrati, Saxifragetum cossonianae, Saxifragetum latepetiolatae y Homalothecio-Asplenietum fontani. Se presentan sendas tablas fitosociológicas de cada una de las tres últimas, de las cuales se comentan, asimismo, sus principales notas características. The communities included in the alliance Homalothecio-Polypodio serrati are studied in Valencia region and neighbouring areas. 4 associations can be assigned to them: Anomodonio-Polypodietum serrati, Saxifragetum cosson…

Patients' and physicians' preferences for type 2 diabetes mellitus treatments in Spain and Portugal: a discrete choice experiment.

2015

Objective: To assess Spanish and Portuguese patients' and physicians' preferences regarding type 2 diabetes mellitus (T2DM) treatments and the monthly willingness to pay (WTP) to gain benefits or avoid side effects. Methods: An observational, multicenter, exploratory study focused on routine clinical practice in Spain and Portugal. Physicians were recruited from multiple hospitals and outpatient clinics, while patients were recruited from eleven centers operating in the public health care system in different autonomous communities in Spain and Portugal. Preferences were measured via a discrete choice experiment by rating multiple T2DM medication attributes. Data were analyzed using the cond…