Search results for "ZEPA"
showing 10 items of 106 documents
CCDC 908613: Experimental Crystal Structure Determination
2015
Related Article: Pawel Jewula, Jean-Claude Berthet, Jean-Claude Chambron, Yoann Rousselin, Pierre Thuéry, Michel Meyer|2015|Eur.J.Inorg.Chem.||1529|doi:10.1002/ejic.201403206
CCDC 906040: Experimental Crystal Structure Determination
2013
Related Article: B.P.Waldron, D.Parker, C.Burchardt, D.S.Yufit, M.Zimny, F.Roesch|2013|Chem.Commun.|49|579|doi:10.1039/c2cc37544c
CCDC 906036: Experimental Crystal Structure Determination
2013
Related Article: B.P.Waldron, D.Parker, C.Burchardt, D.S.Yufit, M.Zimny, F.Roesch|2013|Chem.Commun.|49|579|doi:10.1039/c2cc37544c
CCDC 782535: Experimental Crystal Structure Determination
2010
Related Article: K.Ejsmont, J.Boeglin, C.Didierjean, G.Guichard, C.Jelsch|2010|Acta Crystallogr.,Sect.C:Cryst.Struct.Commun.|66|o292|doi:10.1107/S0108270110016331
Qualitative and quantitative analysis of the phenazepam tablets 12 years after manufacturing
2007
Characterization of the binding of benzodiazepines to human serum albumin
1973
The binding of eleven benzodiazepine derivatives to human serum albumin (HSA) was determined by means of sephadex gel filtration. The albumin binding of the substances was characterized by the percentage of bound drug, the binding constants k +, K 1 and m, the number of binding sites per albumin molecule, and the free binding energy. Under the conditions chosen in these experiments there seems to exist only one binding site of the same type for all investigated benzodiazepines at the HSA molecule. The affinities of the benzodiazepines to this binding site are very different. It is discussed which part of the benzodiazepine molecule represents the main binding group.
Synthesis, benzodiazepine receptor binding and molecular modelling of isochromeno[4,3-c]pyrazol-5(1H)-one derivatives
2012
Abstract A series of isochromeno[4,3-c]pyrazole-5(1H)-one derivatives 7b–h were prepared and tested at 10 μM for their ability to displace specific [3H]flunitrazepam from bovine brain membranes. The substitution pattern of the above derivatives was shown to influence the receptor affinity. The most active compound of the series was 7e, showing a 54% inhibition of [3H]flunitrazepam binding. Compounds 7a–d,i were compared with the known isomers chromeno[4,3-c]pyrazole-4(1H)-ones 14a–d,i, showing that the isochromene/chromene isomerism influences the activity.
Gwara w twórczości nowej fali prozaików śląskich. Wojciech Kuczok i Szczepan Twardoch
2016
Wojciech Kuczok and Szczepan Twardoch are prominent writers of Silesian origins. Their opuses, in particular Kuczok’s Gnój and Twardoch’s Drach occupy prized place in modern Polish literature. Both authors apply native dialect in their literary works. Regarding the subject of their works and the use of linguistic materiał it is impossible to separate the conclusions from the analysis from the perennial discussions about the culture and Silesian language. The literary output of both authors inscribe in the above mentioned discourse. Thus the linguacultural picture, presented as a part of world depicted in their works, is very important. For many readers from outside Silesia, Kuczok and Tward…
Renowacja zabytkowych organów świdnickiej firmy Schlag & Söhne w kościele filialnym pw. Matki Bożej Różańcowej w Szczepanowie (diecezja świdnicka)
2019
Celem niniejszego artykułu jest udokumentowanie przeprowadzonych w 2017 roku prac konserwatorskich przy organach kościoła filialnego w Szczepanowie. Instrument ten został wybudowany w 1882 roku przez fabrykę organową Schlag & Söhne ze Świdnicy i oznaczony jako opus 213 firmy. Organy posiadają dziewięć głosów rozdzielonych na dwa manuały i pedał, mechaniczną trakturę rejestrów i gry oraz wiatrownice z wiszącymi klapami. Remont organów prowadzono od sierpnia do listopada 2017 roku. Jego wykonawcą był zakład organmistrzowski Antoniego Szydłowskiego z Mędłowa. Organom przywrócono pełną sprawność techniczną i brzmieniową. Dokonano pełnej rewaloryzacji wszystkich elementów instrumentu. Zainstalow…
Functionalized Dialdehydes as Promising Scaffolds for Access to Heterocycles and β-Amino Acids: Synthesis of Fluorinated Piperidine and Azepane Deriv…
2017
Functionalized dialdehydes are considered important substrates that can be transformed into various substituted heterocyclic, alicyclic, and polysubstituted compounds. Here, we report a robust stereocontrolled procedure for the synthesis of novel functionalized trifluoromethyl-containing piperidine and azepane derivatives, based on oxidative ring cleavage of the C=C bond of diversely substituted cycloalkenes, followed by reductive ring closure of the diformyl intermediates in the presence of fluorine-containing amines.