Search results for "Zen"

Latvijas Universitātes Raksti; 777 .sēj.

2011

RELATIONSHIP BETWEEN CITIZENS’ TRUST IN LOCAL GOVERNMENT AND PARTICIPATION IN LOCAL GOVERNANCE

2021

The article analyses the relationship between citizens’ trust in local government institutions and participation in local governance. The research results have revealed that citizens’ trust in local government is still low and participation lacks activeness. Civic participation is more active than political participation. According to the research results, the main reasons of absence of participation in local governance are lack of information and knowledge about public participation, lack of information about participation opportunities, lack of communication and response to expressed opinion and suggestions. The results of quantitative research showed that participation and trust dimensio…

ASV prezidenta kandidātu Donalda Trampa un Hilarijas Klintones reprezentācija ziņu portālos “cnn.com”, “bbc.com” un “delfi.lv”, laikposmā no 2016. ga…

2017

Bakalaura darba tēma ir „ASV prezidenta kandidātu Donalda Trampa un Hilarijas Klintones reprezentācijas ziņu portālos CNN.com, BBC.com un DELFI.lv laika posmā no 2016. gada 1. marta līdz 2016. gada 7. novembrim”. Darba mērķis ir noskaidrot, kādas Hilarijas Klintones un Donalda Trampa sociālās reprezentācijas fiksējamas interneta ziņu portālu CNN (ASV), BBC (Apvienotā Karaliste) un Delfi.lv (Latvija) publikācijās un to lietotāju komentāros. Teorijas daļā iekļautas sociālkonstruktīvisma un sociālo reprezentāciju teorijas, kā arī raksturota politiskā komunikācija ASV vēlēšanu cīņu kontekstā. Metodoloģiskajā daļā raksturotas izmantotās pētniecības metodes – kvantitatīvā un kvalitatīvā kontentan…

Dostojevska reliģiski filosofisko ideju recepcija latviešu filozofu un teologu darbos

2016

Bakalaura darbā “Dostojevska reliģiski filozofisko ideju recepcija latviešu filozofu un teologu darbos” tiek salīdzināti un analizēti Zentas Mauriņas un Alberta Freija pētījumi par izcilā krievu rakstnieka un psiholoģiskās prozas meistara Fjodora Dostojevska daiļradē sastopamajām reliģiski filozofiskajām idejām. Viņu pētījumu uzmanības centrā ir tādi F.Dostojevskim tuvi jēdzieni kā Dievs, nemirstība un cilvēks, kā arī paša F.Dostojevska pasaules redzējums. Pirmajā nodaļā tiek aplūkotas latviešu rakstnieces Z. Mauriņas domas par krievu lielmeistara reliģiskajām un filozofiskām idejām, kā arī kritika par F.Dostojevskim veltīto monogrāfiju. Otrajā nodaļā tiek skatīta un analizēta latviešu teol…

Per una Carta de Drets Socials com a procés de construcció de la ciutadania social comunitària

2012

The public system of Social Services is suffering an unprecedented government attack, using the global crisis as an excuse. Their plan is to ruin the social achievements that are the foundations of our Democracy, just when the social inequality is so blatant. Therefore, we would like to do our bit by proposing the implementation of a new process that contributes to strengthen the Community participation.

L'accès au droit et à la justice des citoyens en République centrafricaine

2013

Located at the center of Africa, Oubangui Chari, ex French colony reached independence August 13th, 1960 and became the Central Africa Republic. The applicable duty and the legal organization remained strongly influenced by the legal culture of France, some not hesitating to speak about true imitation. Apart from a trend use the technique of “copy-sticking”, it is important to stress that the French right remains applicable on the Central Africa territory under the terms of the PLANTEY ordinance of October 6th, 1958 which granted survival, in the new States having reached independence, with the colonial texts as long as the local legislative power would not have had which in differently…It …

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance.

2020

Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized as nuclei of great value for obtaining molecules with various biological activities, including analgesic, anti-inflammatory, anti-HIV, antidiabetic, antitumor, and antimicrobial. In particular, in the past decade, many compounds bearing these heterocycles have been studied for their promising antibacterial properties due to their action on different microbial targets. Here we assess the recent development of this class of compounds to address mechanisms underlying antibiotic resistance at both bacterial-cell and community levels (biofilms). We also explore the SAR and the prospective clinical applicati…

Efficacy of budesonide-loaded mesoporous silica microparticles capped with a bulky azo derivative in rats with TNBS-induced colitis.

2019

Abstract A colon targeted drug delivery system for inflammatory bowel diseases (IBD), consisting in budesonide loaded mesoporous silica microparticles functionalized with a selective azo-molecular gate (M-Bud), has been evaluated for in vivo efficacy. Experimental colitis in male Wistar rats was induced by rectal instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS). M-Bud was orally administered to the rats as a suspension in water. Colon/body weight ratio, clinical activity score, and histological evaluation were used as inflammatory indices to measure the performance of the microparticles. The formulation was compared with a suspension prepared from the commercial drug Entocord®. Sta…

Development of an ion-pair to improve the colon permeability of a low permeability drug: Atenolol.

2016

Abstract To ensure the optimal performance of oral controlled release formulations, drug colon permeability is one of the critical parameters. Consequently developing this kind of formulations for low permeability molecules requires strategies to increase their ability to cross the colonic membrane. The objective of this work is to show if an ion-pair formation can improve the colon permeability of atenolol as a low permeability drug model. Two counter ions have been tested: brilliant blue and bromophenol blue. The Distribution coefficients at pH 7.00 (DpH7) of atenolol, atenolol + brilliant blue and atenolol + bromophenol blue were experimentally determined in n-octanol. Moreover, the colo…

Ion-pair approach coupled with nanoparticle formation to increase bioavailability of a low permeability charged drug.

2018

Abstract Atenolol is a drug widely used for the treatment of hypertension. However, the great drawback it presents is a low bioavailability after oral administration. To obtain formulations that allow to improve the bioavailability of this drug is a challenge for the pharmaceutical technology. The objective of this work was to increase the rate and extent of intestinal absorption of atenolol as model of a low permeability drug, developing a double technology strategy. To increase atenolol permeability an ion pair with brilliant blue was designed and the sustained release achieved through encapsulation in polymeric nanoparticles (NPs). The in vitro release studies showed a pH-dependent relea…