Search results for "Zygomycosis"

showing 6 items of 6 documents

Imaging features of perineural and perivascular spread in rapidly progressive rhino-orbital-cerebral mucormycosis: A case report and brief review of …

2021

Background: Rhinocerebral mucormycosis (ROCM) is an opportunistic fungal infection originating from the paranasal sinuses with extension to the brain. A delayed diagnosis can rapidly result in a poor prognosis. ROCM commonly affects patients with diabetes or immunocompromised states with a variable progression. Case Description: We report the case of a 59-year old patient with an untreated diabetes who developed a ROCM with rapidly progressive neurological symptoms. From the onset of sinus pain, nasal congestion, he rapidly developed facial swelling and masticatory dysfunction. The patient underwent sinus surgery which allowed Rhizopus oryzae to be isolated. Accordingly, a systemic therapy…

0301 basic medicinemedicine.medical_specialtyPerivascular spread030106 microbiologyCase ReportNasal congestionMucormycosi03 medical and health sciences0302 clinical medicineZygomycosisPerineural spreadAmphotericin BDiabetes mellitusOcclusionmedicineMucormycosisbusiness.industryMucormycosisRhinocerebral mucormycosimedicine.diseaseThrombosisSurgeryParanasal sinusesmedicine.anatomical_structureRhinocerebral mucormycosisSurgeryMucormycosis; Perineural spread; Perivascular spread; Rhinocerebral mucormycosis; ZygomycosisNeurology (clinical)Zygomycosismedicine.symptombusiness030217 neurology & neurosurgerymedicine.drug
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Survival in rhino-orbito-cerebral mucormycosis: An international, multicenter ID-IRI study

2022

International audience; BACKGROUND: Mucormycosis is an emerging aggressive mold infection. This study aimed to assess the outcome of hospitalized adults with rhino-orbito-cerebral mucormycosis (ROCM). The secondary objective was to identify prognostic factors in this setting. METHODS: This study was an international, retrospective, multicenter study. Patients’ data were collected from 29 referral centers in 6 countries. All qualified as "proven cases" according to the EORTC/MSGERC criteria. RESULTS: We included 74 consecutive adult patients hospitalized with ROCM. Rhino-orbito-cerebral type infection was the most common presentation (n = 43; 58.1%) followed by rhino-orbital type (…

AdultAntifungal AgentsSurveillanceNeutropeniaEpidemiologyMucormycosiInfectionsHospital-acquired infectionRhino-orbito-cerebral mucormycosisZygomycosis[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyDebridementRisk FactorsDiagnosisOrbital DiseasesRisk Factors.Internal MedicineHumansMucormycosisRhino-orbito-cerebral mucormycosiEye Infections FungalRetrospective Studies
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Zygomycosis in Italy: A survey of FIMUA-ECMM (Federazione Italiana di Micopatologia Umana ed Animale and European Confederation of Medical Mycology)

2009

Abstract The aims of the study were to analyze the clinical and epidemiological characteristics and treatments for patients who developed zygomycosis enrolled in Italy during the European Confederation of Medical Mycology of medical mycology survey. This prospective multicenter study was performed between 2004 and 2007 at 49 italian Departments. 60 cases of zygomycosis were enrolled: the median age was 59.5 years (range 1-87), with a prevalence of males (70%). The majority of cases were immunocompromised patients (42 cases, 70%), mainly hematological malignancies (37). Among non-immunocompromised (18 cases, 30%), the main category was represented by patients with penetrating trauma (7/18, 3…

AdultMalemedicine.medical_specialtyAdolescentEpidemiologyAntifungal drugImmunocompromised HostPharmacotherapyZygomycosisDrug Resistance FungalAmphotericin BInternal medicineEpidemiologymedicineHumansPharmacology (medical)ChildMycosisAgedPharmacologyImmunocompromised hostAged 80 and overbusiness.industryMortality rateMucormycosisInfantEpidemiology; Immunocompromised host; ZygomycosisMiddle Agedmedicine.diseaseSurgeryInfectious DiseasesOncologyItalyChild PreschoolFemaleZygomycosisbusinessmedicine.drug
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Forty-one recent cases of invasive zygomycosis from a global clinical registry.

2009

Background Invasive zygomycosis accounts for a significant proportion of all invasive fungal diseases (IFD), but clinical data on the clinical course and treatment response are limited. Patients and methods Fungiscope-A Global Rare Fungal Infection Registry is an international university-based case registry that collects data of patients with rare IFD, using a web-based electronic case form at www.fungiscope.net. Results Forty-one patients with invasive zygomycosis from central Europe and Asia were registered. The most common underlying conditions were malignancies (n = 26; 63.4%), diabetes mellitus (n = 7; 17.1%) and solid organ transplantation (n = 4; 9.8%). Diagnosis was made by culture …

Microbiology (medical)AdultMalemedicine.medical_specialtyPosaconazoleAntifungal AgentsAsiaAdolescentDatabases FactualItraconazoleDiabetes ComplicationsImmunocompromised HostYoung AdultZygomycosisAmphotericin BInternal medicineAmphotericin BNeoplasmsmedicineHumansPharmacology (medical)ChildSurvival analysisMycosisAgedPharmacologyAged 80 and overbusiness.industryMucormycosisOrgan TransplantationMiddle Agedmedicine.diseaseSurvival AnalysisSurgeryEuropeInfectious DiseasesTreatment OutcomeChild PreschoolChemoprophylaxisMucoralesFemaleZygomycosisbusinessmedicine.drugThe Journal of antimicrobial chemotherapy
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Mucormycosis of maxilla following tooth extraction in immunocompetent patients : reports and review

2018

Mucormycosis is a rare, fulminant, rapidly spreading fungal infection, which usually affects patient with underlying immune deficiency. If not managed promptly, the disease is characterized by progressive necrosis and is often fatal. A review of English literature shows that only fourteen cases of mucormycosis have been reported after tooth extraction. This paper highlights two cases of mucormycosis subsequent to tooth extraction in healthy adult patients. This first patient presented with an oroantral fistula and extensive maxillary necrosis. Whereas the second case was localized and presented as non-healing extraction socket with alveolar necrosis. This adds two more cases of this rare an…

medicine.medical_specialtyNecrosisAdult patientsbusiness.industryFulminantMucormycosisCase Report030206 dentistrymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Surgery03 medical and health sciences0302 clinical medicineOroantral fistulaMaxillaUNESCO::CIENCIAS MÉDICASmedicineZygomycosismedicine.symptomOral SurgeryComplicationbusinessGeneral Dentistry030217 neurology & neurosurgery
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Forty-One Recent Cases of Invasive Zygomycosis From a Global Clinical Registry.

2009

Abstract Abstract 4736 Background Invasive zygomycosis accounts for a significant proportion of all invasive fungal diseases (IFD), but clinical data on the clinical course and treatment response is limited. Methods Fungiscope” - A Global Rare Fungal Infection Registry is a university-based case registry that collects data of patients with rare IFD, using a web-based electronic case form at www.fungiscope.net. Results Fourty-one patients with invasive zygomycosis were registered. Five were pediatric (12.2%), 28 (68.3%) male. Median age was 49 years (range 2-88). Most common underlying conditions were malignancies (n=26; 63.4%), diabetes mellitus (n=7; 17%) and solid organ transplant (n=4; 9…

medicine.medical_specialtyTreatment responsebusiness.industryImmunologyClinical courseCell BiologyHematologymedicine.diseaseBiochemistryFAVORABLE RESPONSEFamily medicinemedicineClinical registryIn patientZygomycosisSolid organ transplantationbusinessEmpiric treatmentBlood
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