Search results for "actin"

ChemInform Abstract: New Developments in Nitrogen Fixation.

2010

The production of ammonia from atmospheric dinitrogen at room temperature and ambient pressure in analogy to nature is a long-term goal for coordination chemists. Novel reactions of N2 -containing transition metal complexes with H2 , the first side-on N2 -bridged structure of an actinide complex, and an interesting variation of synthetic N2 fixation are the key points addressed in this contribution. The results are related to the known chemistry of N2 complexes, and their significance is discussed with respect to enzymatic N2 fixation.

Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors

1998

PURPOSE:To examine the apoptotic effect induced in human retinoblastoma Y79 cells by camptothecin, etoposide, and amsacrine, to examine the effect of these drugs on the expression of many apoptosis-related modulators, and to test the antiapoptotic effect exerted by insulin-like growth factor-I (IGF-I). METHODS:Morphologic features of apoptosis were demonstrated using acridine orange- ethidium bromide staining and electron microscopy. DNA fragmentation was determined by means of an in situ cell detection procedure (TdT-dUTP terminal nick-end labeling [TUNEL]) or by electrophoresis on agarose gels and was quantified by enzyme-linked immunosorbent assay. The expression of apoptosis-related mod…

Some aspects of the recovery of chlorinated residues (DDT-type compounds and PCB) from fish tissue by using different extraction methods

1974

Photon absorption by aqueous TiO2 dispersion contained in a stirred photoreactor

1991

We present a simple experimental method which allows the evaluation of the absorbed photon flow. The method is based on measurements of transmitted photon rates (by means of standard actinometer solutions) for different reactor thicknesses and/or catalyst concentrations. The method was applied to phenol degradation reaction carried out in a stirred batch phtotoreactor containing aqueous TiO 2 (anatase) dispersion, directly irradied by a 1,500 W Xe lamp

Metabolic impact of adult-onset, isolated, growth hormone deficiency (AOiGHD) due to destruction of pituitary somatotropes.

2011

Growth hormone (GH) inhibits fat accumulation and promotes protein accretion, therefore the fall in GH observed with weight gain and normal aging may contribute to metabolic dysfunction. To directly test this hypothesis a novel mouse model of adult onset-isolated GH deficiency (AOiGHD) was generated by cross breeding rat GH promoter-driven Cre recombinase mice (Cre) with inducible diphtheria toxin receptor mice (iDTR) and treating adult Cre(+/-), iDTR(+/-) offspring with DT to selectively destroy the somatotrope population of the anterior pituitary gland, leading to a reduction in circulating GH and IGF-I levels. DT-treated Cre(-/-), iDTR(+/-) mice were used as GH-intact controls. AOiGHD im…

The Active Human Gut Microbiota Differs from the Total Microbiota

2011

The human gut microbiota is considered one of the most fascinating reservoirs of microbial diversity hosting between 400 to 1000 bacterial species distributed among nine phyla with Firmicutes, Bacteroidetes and Actinobacteria representing around of the diversity. One of the most intriguing issues relates to understanding which microbial groups are active players in the maintenance of the microbiota homeostasis. Here, we describe the diversity of active microbial fractions compared with the whole community from raw human fecal samples. We studied four healthy volunteers by 16S rDNA gene pyrosequencing. The fractions were obtained by cell sorting based on bacterial RNA concentration. Bacteria…

Efisiensi Biaya Pakan Melalui Pemanfaatan Rayap Pohon (Coptotermes sp.) dalam Pembesaran Ikan Mas Komet(Carassius auratus auratus)

2017

Tujuan penelitian ini yaitu mengetahui pertumbuhan relatif ikan mas komet dengan persentasi pakan rayap dan pelet, rasio konversi pakan dan efisiensi pakan dari masing-masing perlakuan, dan menganalisis biaya pakan yang dikonsumsi. Perlakuan pada penelitian ini menggunakan pakan rayap dan pelet dengan persentase yang berbeda. Perlakuan A = rayap 20% ; pelet 80%, B = rayap 40% ; pelet 60% dan C = rayap 60% ; pelet 40%. Hasil penelitian menunjukkan bahwa persentase pakan rayap dan pelet memberikan pertumbuhan relatif yang lebih baik pada perlakuan A 0,42 gram, B 0,10 gram dan C 0,26 gram. Nilai FCR yang terbaik diperoleh oleh perlakuan A 2,04 diikuti oleh C 3,3 dan B 7,9. Begitu pula dengan n…

GRANULOMATOUS MASTITIS DURING CHRONIC ANTIDEPRESSANT THERAPY: IS IT POSSIBLE A CONSERVATIVE THERAPEUTIC APPROACH?

2012

Granulomatous mastitis is a rare benign inflammatory disease of the breast with multiple etiologies such as tuberculosis, sarcoidosis, foreign body reaction, and mycotic and parasitic infections. In contrast, idiopathic granulomatous mastitis (IGM) is characterized by the presence of chronic granulomatous lobulitis in the absence of an obvious etiology. Clinically and radiologically it may mimic breast carcinoma and so awareness of surgeons, pathologists, and radiologists is essential to avoid unnecessary mastectomies. Cases of IGM are reported during antidepressant therapy in patients also showing high levels of prolactinemia. In these cases, we believe that surgical excision must be avoid…

Dexamethasone modulates α2-macroglobulin and apolipoprotein E gene expression in cultured rat liver fat-storing (Ito) cells

1991

Fat-storing (Ito) cells are perisinusoidal liver cells thought to play a central role in vitamin A metabolism and fibrogenesis. Glucocorticoids have been shown to be beneficial in the treatment of certain types of liver diseases by delaying the development of cirrhosis. To study the regulatory effects of dexamethasone on Ito cell gene expression, Ito cells were isolated from normal rat liver and primary cultures were established. The effect of dexamethasone on the synthesis of α2-macroglobulin, apolipoprotein E, fibronectin and actin was examined. Protein synthesis was studied both at the protein level and at the RNA level by means of biosynthetic labeling, immunoprecipitation followed by s…

Domain decomposition in the symmetric boundary element analysis

2002

Recent developments in the symmetric boundary element method (SBEM) have shown a clear superiority of this formulation over the collocation method. Its competitiveness has been tested in comparison to the finite element method (FEM) and is manifested in several engineering problems in which internal boundaries are present, i.e. those in which the body shows a jump in the physical characteristics of the material and in which an appropriate study of the response must be used. When we work in the ambit of the SBE formulation, the body is subdivided into macroelements characterized by some relations which link the interface boundary unknowns to the external actions. These relations, valid for e…