Search results for "active"

Cellular mechanisms of IL-17-induced blood-brain barrier disruption.

2009

Recently T-helper 17 (Th17) cells were demonstrated to disrupt the blood-brain barrier (BBB) by the action of IL-17A. The aim of the present study was to examine the mechanisms that underlie IL-17A-induced BBB breakdown. Barrier integrity was analyzed in the murine brain endothelial cell line bEnd.3 by measuring the electrical resistance values using electrical call impedance sensing technology. Furthermore, in-cell Western blots, fluorescence imaging, and monocyte adhesion and transendothelial migration assays were performed. Experimental autoimmune encephalomyelitis (EAE) was induced in C57BL/6 mice. IL-17A induced NADPH oxidase- or xanthine oxidase-dependent reactive oxygen species (ROS)…

Stereochemical features of the hydrolysis of 9,10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases

2002

cis-9,10-Epoxystearic acid was used as a tool to probe the active sites of epoxide hydrolases (EHs) of mammalian and plant origin. We have compared the stereochemical features of the hydrolysis of this substrate catalysed by soluble and membrane-bound rat liver EHs, by soluble EH (purified to apparent homogeneity) obtained from maize seedlings or celeriac roots, and by recombinant soybean EH expressed in yeast. Plant EHs were found to differ in their enantioselectivity, i.e. their ability to discriminate between the two enantiomers of 9,10-epoxystearic acid. For example, while the maize enzyme hydrated both enantiomers at the same rate, the EH from soybean exhibited very high enantioselecti…

Effective and environmental half-lives of radiocesium in game from Poland.

2021

For the first time changes in the 137Cs activity in game throughout Poland, including its most contaminated part known as the Opole Anomaly, were analyzed. Due to its long physical half-life, 137Cs continuously demonstrates high activity both in soil and biota. The species of game mammals, along with forest fruit and mushrooms, tend to accumulate this radionuclide, becoming one of the main sources of secondary contamination in people. In this study the 137Cs activity in roe deer, wild boar and red deer muscle tissue samples, within the years of 1986–2019, were studied. The effective and environmental half-lives were determined for each of the mentioned species for four regions including NE …

First M87 Event Horizon Telescope Results. VII. Polarization of the Ring

2021

Full list of authors: Akiyama, Kazunori; Algaba, Juan Carlos; Alberdi, Antxon; Alef, Walter; Anantua, Richard; Asada, Keiichi; Azulay, Rebecca; Baczko, Anne-Kathrin; Ball, David; Baloković, Mislav; Barrett, John; Benson, Bradford A.; Bintley, Dan; Blackburn, Lindy; Blundell, Raymond; Boland, Wilfred; Bouman, Katherine L.; Bower, Geoffrey C.; Boyce, Hope Bremer, Michael; Brinkerink, Christiaan D.; Brissenden, Roger; Britzen, Silke; Broderick, Avery E.; Broguiere, Dominique; Bronzwaer, Thomas; Byun, Do-Young; Carlstrom, John E.; Chael, Andrew; Chan, Chi-kwan; Chatterjee, Shami; Chatterjee, Koushik; Chen, Ming-Tang; Chen, Yongjun; Chesler, Paul M.; Cho, Ilje; Christian, Pierre; Conway, John E.…

Evaluation of the 2-Methoxyethanol as Entrainer in Ethanol–Water and 1-Propanol–Water Mixtures

2013

In this paper, 2-methoxyethanol (commercially known as methyl cellosolve) is proposed as a potential entrainer for extractive distillation processes involving water–alcohol mixtures. The two alcohols studied in this work are ethanol and 1-propanol. Thereby, isobaric vapor–liquid equilibrium (VLE) data at atmospheric pressure have been measured for the ternary systems ethanol + water + 2-methoxyethanol and 1-propanol + water + 2-methoxyethanol. Moreover, data of the binary systems formed by the 2-methoxyethanol and each of the other chemicals used (ethanol, water, 1-propanol) have been obtained. The well-known local composition models Wilson, UNIQUAC, and NRTL have been used to correlate bin…

Investigations in intensification of grain drying by active ventilation applying ozone

2020

The financial support of the Rural Support Service project No l8-00-A01620-000003 “Technology development of grain drying with active ventilation using ozone” is greatly acknowledged. The authors thank for the support and active cooperation the representatives of the farm “Mazkalniņi” Dr.sc.ing. Aivars Cēsnieks and ing. Sandris Cēsnieks.

Dual Careers of Athletes During COVID-19 Lockdown

2021

This study aimed to investigate the student-athletes' capability to face the academic, sport, and social challenges during the coronavirus disease 2019 (COVID-19) lockdown and to disclose novel aspects of dual careers. A 32-item online survey encompassing demographic characteristics, sport and university engagement, support and dual-career benefits, physical activity, sitting time, and the time deemed necessary to recover the previous level of performance was developed. Four hundred sixty-seven student-athletes (males: 57%, females: 43%) from 11 countries, competing in 49 different sports (individual: 63.4%, team: 36.6%) at regional (17.5%), national (43.3%), and international (39.2%) level…

Presepsin value predicts the risk of developing severe/critical COVID-19 illness: results of a pooled analysis

2021

Course of D-Dimer and C-Reactive Protein Levels in Survivors and Nonsurvivors with COVID-19 Pneumonia: A Retrospective Analysis of 577 Patients

2020

Spectroscopic studies of neutron-deficient light nuclei: decay properties of 21Mg, 25Si and 26P

2003

Neutron‐deficient nuclei with Tz equals to −3/2 and −2 have been produced at the GANIL/LISE3 facility in fragmentation reactions of a 95 MeV/u 36Ar primary beam in a 12C target. For the first time, β‐delayed proton and β‐γ emission has been simultaneously observed in the decay of 21Mg, 25Si and 26P. The decay scheme of the latter is proposed and the Gamow‐Teller strength distribution in its β decay is compared to shell‐model calculations based on the USD interaction. The B(GT) values derived from the absolute measurement of the β‐branching ratios are in agreement with the quenching factor of about 60% obtained for allowed Gamow‐Teller transitions in this mass region. A precise half‐life of …