Search results for "active"

Etanercept maintains the clinical benefit achieved by infliximab in patients with rheumatoid arthritis who discontinued infliximab because of side ef…

2007

Objective: To evaluate the efficacy of switching to etanercept treatment in patients with rheumatoid arthritis who already responded to infliximab, but presented side effects. Methods: Charts of 553 patients with rheumatoid arthritis were retrospectively reviewed to select patients who responded to the treatment with infliximab and switched to etanercept because of occurrence of adverse effects. Clinical data were gathered during 24 weeks of etanercept treatment and for the same period of infliximab treatment before infliximab was stopped. Disease Activity Score computed on 44 joints (DAS-44), erythrocyte sedimentation rate (ESR) 1st hour, Visual Analogue Scale (VAS) of pain, Health Assessm…

Why Use Interactive Multi-Objective Optimization in Chemical Process Design?

2008

Problems in chemical engineering, like most real-world optimization problems, typically, have several conflicting performance criteria or objectives and they often are computationally demanding, which sets special requirements on the optimization methods used. In this chapter, we point out some shortcomings of some widely used basic methods of multi-objective optimization. As an alternative, we suggest using interactive approaches where the role of a decision maker or a designer is emphasized. Interactive multi-objective optimization has been shown to suit well for chemical process design problems because it takes the preferences of the decision maker into account in an iterative manner tha…

Seismotectonics in the North-Western Sicily Continental Margin: implications for Geohazard assessment

2017

Active processes in the Northern Sicily Continental Margin (NSCM) have been analysed to produce a seismotectonic map, in order to obtain a useful tool for the assessment of the seismic hazard of the sea-land region. The seismotectonic map is composed of overlapping layers that represent the distribution of different features, such as lithostratigraphy, tectonic elements, seismicity, heat flow, gravimetry, magnetometry, Moho depth, horizontal and vertical movements, submarine landslides, fluid emissions, outlining the mutual relationship and the active structures. The NSCM is suitable to test this approach because it’s located in a transitional area between the Sicilian-Maghrebian chain to t…

SEISMOTECTONIC MAP OF THE NORTHERN SICILY CONTINENTAL MARGIN (NSCM) AND IMPLICATIONS FOR GEOHAZARD ASSESSMENT

2018

The Sicily dominates the central Mediterranean Sea. The Northern Sicily Continental Margin (NSCM) is a segment of the Appeninic-Tyrrhenian System whose upbuilding refers to both the postcollisional convergence between Africa and a very complex “European” crust (Bonardi et al., 2001) or AlKaPeKa (sensu Boullin, 1986) and the opening of the Tyrrhenian back-arc basin. Seismostratigraphic and structural analysis of a large number of available (from ViDePi project) and unpublished (from Department of Earth and Marine Science of the University of Palermo) multichannel seismic reflection profiles acquired across the NSCM, allow us to produce an accurate seismotectonic map, in order to obtain a use…

Is individual- and school-level teacher burnout reduced by proactive strategies?

2021

There is provisional evidence that burnout may be contagious within professional communities via the crossover effect, referring to an inter-individual transmission of stress or strain. However, our understanding of effective means for tackling stressors is scarce. We tested a two-level path model to explore the interrelation between teachers’ proactive self- and co-regulative strategies and experienced burnout. The study sample comprised 1531 Finnish in-service teachers from 75 schools. The results showed that burnout symptoms varied both between individual teachers and between professional communities. Self- and co-regulative strategies serve partly different functions in regulating teach…

Gaussian processes retrieval of crop traits in Google Earth Engine based on Sentinel-2 top-of-atmosphere data.

2022

The unprecedented availability of optical satellite data in cloud-based computing platforms, such as Google Earth Engine (GEE), opens new possibilities to develop crop trait retrieval models from the local to the planetary scale. Hybrid retrieval models are of interest to run in these platforms as they combine the advantages of physically-based radiative transfer models (RTM) with the flexibility of machine learning regression algorithms. Previous research with GEE primarily relied on processing bottom-of-atmosphere (BOA) reflectance data, which requires atmospheric correction. In the present study, we implemented hybrid models directly into GEE for processing Sentinel-2 (S2) Level-1C (L1C)…

Looking ahead in games research

2021

This thematic issue presents a number of emerging scholarships into the study of digital gaming. The articles are based on a 2019 symposium on game studies hosted by the Digital Games Research section of ECREA. As the phenomena related to digital gaming keep on evolving and emerging, so must research keep up with the times and constantly challenge itself. Whether speaking about validating previously developed research methods, imagining totally new ones, or even challenging the whole philosophy of science on which research is being done, there is a constant need for reappraisal and introspection within games research. As a cultural medium that has become deeply embedded into the social fabr…

A 10-Week Block of Combined High-Intensity Endurance and Strength Training Produced Similar Changes in Dynamic Strength, Body Composition, and Serum …

2020

Purpose: To examine the potential sex differences in adaptations to combined endurance and strength training in recreationally endurance trained (eumenorrheic) women (n = 9) and men (n = 10). Methods: Isometric (ISOMmax) and dynamic bilateral leg press (1RM), countermovement jump (CMJ), running performance (3,000 m time trial), lean mass and body fat % (LEAN and FAT% determined by dual X-ray absorptiometry) as well as serum testosterone and cortisol (TES and COR, respectively, measured using hormone-specific immunoassay kits) were examined before a control period and pre, mid, and post a supervised 10-week combined high-intensity interval endurance training (4 × 4 min intervals and 3 × 3 × …

Innovative technologies for packaging, preservation, shelf-life extension and traceability of the aquaculture and fishery products

2022

Milk Thistle (Silybum Marianum L.) as a Novel Multipurpose Crop for Agriculture in Marginal Environments: A Review

2022

Milk thistle (Silybum marianum (L.) Gaertn.) is a versatile crop that has adapted to the broadly different soil and environmental conditions throughout all continents. To date, the fruits (“seeds”) of the plant are the only reliable source of silymarin, which, given its recognized therapeutic effects and its many present and potential uses, has led to a significant re-discovery and enhancement of the crop in recent years. Overall, although many studies have been carried out globally on the bioactivity, phytochemistry, and genetics of milk thistle, few and discontinuous research activity has been conducted on its basic agronomy as well as on the farm opportunities offered by the cultivation …