Search results for "active"

showing 10 items of 5361 documents

Immune activation increases susceptibility to oxidative tissue damage in Zebra Finches.

2006

Summary 1The innate immune response involves the production of highly reactive molecules (reactive oxygen and nitrogen species, ROS and RNS). These toxic compounds can effectively destroy invading pathogens but can also, non-specifically, target host cells. Tissue damage caused by ROS and RNS can be substantial if the inflammatory response is overactive, potentially inducing a so-called immunopathology. 2In this study, we induced an inflammatory response in Zebra Finches by the way of a LPS injection (lipopolysaccharide of the cell wall of Escherichia coli), using as a control a group of birds injected with saline (phosphate-buffered saline). Body mass was measured both before and 24 h afte…

0106 biological sciencesLipopolysaccharidefree radicals[ SDV.BBM.BM ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyBiologymedicine.disease_cause010603 evolutionary biology01 natural sciencesimmune activation03 medical and health scienceschemistry.chemical_compoundImmune systemnitric oxideImmunopathologymedicine[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyimmunopathologyZebra finchEcology Evolution Behavior and SystematicsReactive nitrogen speciesComputingMilieux_MISCELLANEOUS030304 developmental biologyZebra Finchchemistry.chemical_classification0303 health sciencesReactive oxygen speciesInnate immune systemlipopolysaccharide[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biology3. Good healthchemistryImmunology[SDV.IMM]Life Sciences [q-bio]/ImmunologyOxidative stress
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Activation of a nuclear-localized SIPK in tobacco cells challenged by cryptogein, an elicitor of plant defence reactions.

2009

When a plant cell is challenged by a well-defined stimulus, complex signal transduction pathways are activated to promote the modulation of specific sets of genes and eventually to develop adaptive responses. In this context, protein phosphorylation plays a fundamental role through the activation of multiple protein kinase families. Although the involvement of protein kinases at the plasma membrane and cytosolic levels are now well-documented, their nuclear counterparts are still poorly investigated. In the field of plant defence reactions, no known study has yet reported the activation of a nuclear protein kinase and/or its nuclear activity in plant cells, although some protein kinases, e.…

0106 biological sciencesMAPK/ERK pathwayMolecular Sequence DataActive Transport Cell NucleusBiology01 natural sciencesBiochemistryMAP2K703 medical and health sciencesCytosolTobaccoASK1Protein phosphorylation[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyAmino Acid SequenceNuclear proteinProtein kinase AMolecular BiologyConserved Sequence030304 developmental biologyPlant ProteinsCell Nucleus0303 health sciencesKinasePlant ExtractsAlgal ProteinsLife SciencesCell BiologyCell biologyEnzyme ActivationBiochemistrySignal transductionMitogen-Activated Protein KinasesSequence Alignment010606 plant biology & botanySignal TransductionThe Biochemical journal
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Integrated signaling network involving calcium, nitric oxide, active oxygen species but not mitogen-activated protein kinases in BcPG1-elicited grape…

2006

We have already reported the identification of the endopolygalacturonase 1 (BcPG1) from Botrytis cinerea as a potent elicitor of defense responses in grapevine, independently of its enzymatic activity. The aim of the present study is the analysis of the signaling pathways triggered by BcPG1 in grapevine cells. Our data indicate that BcPG1 induces a Ca2+ entry from the apoplasm, which triggers a phosphorylation-dependent nitric oxide (NO) production via an enzyme probably related to a NO synthase. Then NO is involved in i) cytosolic calcium homeostasis, by activating Ca2+ release from internal stores and regulating Ca2+ fluxes across the plasma membrane, ii) plasma membrane potential variat…

0106 biological sciencesMAPK/ERK pathwayTime FactorsPhysiology[SDV]Life Sciences [q-bio]Phenylalanine ammonia-lyase01 natural sciencesNitric oxideFungal Proteins03 medical and health scienceschemistry.chemical_compounddepolarizationGene Expression Regulation Plantplant defensenitric oxideVitisdépolarisationProtein kinase ACells Cultured030304 developmental biology0303 health scienceselicitorbiologyelicitor; grapevine; plant defense; nitric oxideKinaseGeneral MedicinePlants Genetically ModifiedElicitorgrapevinechemistryBiochemistryMitogen-activated protein kinasebiology.proteinCalciumBotrytisMitogen-Activated Protein KinasesSignal transductionbotrytis cinereavigneReactive Oxygen SpeciesAgronomy and Crop ScienceSignal Transduction010606 plant biology & botany
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Genetic correlation between resistance to oxidative stress and reproductive life span in a bird species.

2010

Evolutionary theories propose that aging is the result of a trade-off between self-maintenance and reproduction, and oxidative stress may play a crucial role in such a trade-off. Phenotypic manipulations have revealed that a high investment in reproduction leads to a decline in the organism's resistance to oxidative stress, which could in turn accelerate aging. Here, by using quantitative genetic analyses as a tool to disentangle genetic effects from phenotypic variances, the relationship between resistance to oxidative stress at sexual maturity and two key reproductive life-history traits (i.e., number of breeding events during life and age at last reproduction) was analyzed in cross-foste…

0106 biological sciencesMalequantitative geneticsQuantitative geneticsDisposable-somaFree radicalsmedicine.disease_cause01 natural sciencesreactive oxygen species.PleiotropySexual maturityOrganismmedia_commonGeneticsreactive oxygen species[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciencesReproductionBiological Evolution3. Good healthFemaleReproductionGeneral Agricultural and Biological Sciencesmedia_common.quotation_subjectLongevityfree radicalsBiology010603 evolutionary biologyGenetic correlation[ SDV.EE ] Life Sciences [q-bio]/Ecology environment03 medical and health sciencespleiotropyGeneticsmedicineLife-historyAnimalsEcology Evolution Behavior and SystematicsGenetic Association Studies030304 developmental biologyPleiotropy[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyModels Geneticlife-historyQuantitative geneticsHeritabilityOxidative StressFinches[SDE.BE]Environmental Sciences/Biodiversity and EcologyReactive oxygen speciesOxidative stress
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Biochemical characterization of cassiopea andromeda (Forsskål, 1775), another red sea jellyfish in the western mediterranean sea

2021

Increasing frequency of native jellyfish proliferations and massive appearance of non-indigenous jellyfish species recently concur to impact Mediterranean coastal ecosystems and human activities at sea. Nonetheless, jellyfish biomass may represent an exploitable novel resource to coastal communities, with reference to its potential use in the pharmaceutical, nutritional, and nutraceutical Blue Growth sectors. The zooxanthellate jellyfish Cassiopea andromeda, Forsskål, 1775 (Cnidaria, Rhizostomeae) entered the Levant Sea through the Suez Canal and spread towards the Western Mediterranean to reach Malta, Tunisia, and recently also the Italian coasts. Here we report on the biochemical characte…

0106 biological sciencesMediterranean climateCnidariacollagenAquatic OrganismsJellyfishScyphozoaPharmaceutical Scienceantioxidant activityalien species01 natural sciencesBioactive marine compoundMediterranean seaDrug DiscoverySuez canalAlien species; Antioxidant activity; Antioxidants; Bioactive marine compounds; Collagen; Fatty acids; Jellyfish; Nutraceuticals; Zooxanthellate jellyfish; Animals; Antioxidants; Aquatic Organisms; Ecosystem; Mediterranean Sea; Dietary Supplements; ScyphozoaBiology (General)Pharmacology Toxicology and Pharmaceutics (miscellaneous)nutraceuticals0303 health sciencesAquatic Organismjellyfishzooxanthellate jellyfishAlien species Antioxidant activity Antioxidants Bioactive marine compounds Collagen Fatty acids Jellyfish Nutraceuticals Zooxanthellate jellyfish Animals Antioxidants Aquatic Organisms Ecosystem Mediterranean Sea Dietary Supplements ScyphozoaantioxidantsZooxanthellaeCollagenNutraceuticalAntioxidantCassiopea andromedaQH301-705.5Biologyfatty acids03 medical and health sciencesNutraceuticalAntioxidant activitybiology.animalBotanyMediterranean SeaAnimalsZooxanthellate jellyfish14. Life underwaterAlien specieEcosystem030304 developmental biologyDietary Supplementbioactive marine compoundsAnimal010604 marine biology & hydrobiologybiology.organism_classificationFatty acidDietary SupplementsJellyfish
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Plasma membrane sterol complexation, generated by filipin, triggers signaling responses in tobacco cells

2010

International audience; The effects of changes in plasma membrane (PM) sterol lateral organization and availability on the control of signaling pathways have been reported in various animal systems, but rarely assessed in plant cells. In the present study, the pentaene macrolide antibiotic filipin III, commonly used in animal systems as a sterol sequestrating agent, was applied to tobacco cells. We show that filipin can be used at a non-lethal concentration that still allows an homogeneous labeling of the plasma membrane and the formation of filipin-sterol complexes at the ultrastructural level. This filipin concentration triggers a rapid and transient NADPH oxidase-dependent production of …

0106 biological sciencesMembrane Fluidity[SDV]Life Sciences [q-bio]CellBiophysicsPLANTEBiology01 natural sciencesFilipinBiochemistry03 medical and health scienceschemistry.chemical_compoundTobaccomedicinepolycyclic compoundsMEMBRANE PLASMIQUEFilipinPhosphorylation030304 developmental biologySterolchemistry.chemical_classification0303 health sciencesReactive oxygen speciesCell DeathCell MembranePhytosterolsPlantCell BiologyPlant cellSterolCell biologymedicine.anatomical_structurechemistrySignalizationPotassiumSIGNALISATIONPhosphorylationlipids (amino acids peptides and proteins)sense organsSignal transductionReactive Oxygen SpeciesLaurdanSignal Transduction010606 plant biology & botanyPlasma membraneBiochimica et Biophysica Acta (BBA) - Biomembranes
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Regulation of plant NADPH oxidase.

2007

Addendum to: Regulation of Reactive Oxygen Species Production by a 14-3-3 Protein in Elicited Tobacco Cells. T. Elmayan, J. Fromentin, C. Riondet, G. Alcaraz, J. Blein and F. Simon-Plas. Plant Cell Environ 2007; 30:722–32; International audience; The production of Reactive Oxygen Species (ROS) is one of the key events occurring during the response of plants to environmental changes, and contributing to establish adaptive signaling pathways. A plasma membrane bound NADPH oxidase enzyme has been evidenced as the ROS producing system in various plant‑microorganisms interactions. We very recently reported, that a protein of the 14‑3‑3 family was able to interact directly with the C‑terminus par…

0106 biological sciencesMembrane boundContext (language use)Plant Science01 natural sciences[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health sciences[SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants geneticsNADPH OXIDASEPlant defense against herbivoryREACTIVE OXYGEN SPECIES14-3-3030304 developmental biologyPROTEINE PHOSPHATASE TYPE 2Cchemistry.chemical_classification0303 health sciencesReactive oxygen speciesOxidase testNADPH oxidasebiologyTWO-HYBRIDArticle AddendumEnzymeBiochemistrychemistryREGULATIONbiology.proteinSignal transduction010606 plant biology & botanyPlant signalingbehavior
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Carvacrol activated biopolymeric foam: An effective packaging system to control the development of spoilage and pathogenic bacteria on sliced pumpkin…

2021

Abstract A commercial biodegradable starch-based polymer (Mater-Bi) was activated with carvacrol to develop a biodegradable and compostable polymer to be used in food packaging. Based on previous tests, carvacrol was added at 20 % weight of foam. MB foams, with and without carvacrol, were tested for their morphological characteristics, mechanical tests and kinetics of carvacrol release under refrigerated storage conditions. Carvacrol slightly increased the porosity of the foams, induced a reduction of the compressive elastic modulus (Ecom) of foamed MB from 6 to ∼ 3.4 MPa and a decrease of the tensile elastic modulus from ∼70 MPa to ∼16.5 MPa. Carvacrol release from the foam at 4 °C was alm…

0106 biological sciencesMicrobiology (medical)Polymers and PlasticsMelonStarchFood spoilageActive packagingBiopolymeric foamsSettore AGR/04 - Orticoltura E FloricolturaSpoilage and pathogenic bacteriamedicine.disease_cause01 natural sciencesAntibacterial propertiesBiomaterialsFood packagingchemistry.chemical_compound0404 agricultural biotechnologyListeria monocytogenesCarvacrol010608 biotechnologymedicineCarvacrolFood scienceSafety Risk Reliability and QualityFood model systemsbiologyChemistrySettore ING-IND/34 - Bioingegneria Industriale04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceFood packagingSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiIn vivo activityBacteriaSettore AGR/16 - Microbiologia AgrariaFood ScienceFood Packaging and Shelf Life
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Thermoplastic starch and green tea blends with LLDPE films for active packaging of meat and oil-based products

2019

International audience; Thermoplastic starch (TPS) is an alternative biomaterial that can be used to produce bioplastics to replace petroleum-based food packaging. Active films were developed from acetylated cassava TPS and green tea using the blown extrusion process. Green tea (GT) and TPS from native starch (NS) and acetylated starch (AS) with different degrees of substitution (DS) were extruded with linear low-density polyethylene (LLDPE) at LLDPE/TPS-GT ratios of 70/30 and 60/40 prior to blown-film extrusion. Results indicated that a higher DS of AS enhanced melt flow index which altered processability and subsequently impacted film microstructures and physical and barrier properties. N…

0106 biological sciencesMicrobiology (medical)Polymers and PlasticsStarchActive packaging[SDV.TOX.TCA]Life Sciences [q-bio]/Toxicology/Toxicology and food chain01 natural sciencesBioplasticBiomaterialsLLDPEchemistry.chemical_compoundFood packaging0404 agricultural biotechnologyLipid oxidation010608 biotechnologySafety Risk Reliability and QualityFilmMelt flow indexThermoplastic starchChemistryfood and beverages04 agricultural and veterinary sciences040401 food scienceLinear low-density polyethyleneFood packagingChemical engineeringActive packagingExtrusionAntioxidant[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood Science
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Development of a Bioactive Sauce Based on Oriental Mustard Flour with Antifungal Properties for Pita Bread Shelf Life Improvement

2019

Ochratoxin A (OTA) is a mycotoxin produced in the secondary metabolism of fungus belonging to the genus Aspergillus and Penicillium. In this study, the employment of oriental mustard flour (OMF) as an ingredient in a packaged sauce was evaluated for the generation in situ of the antimicrobial compound allyl isothiocyanate (AITC) in order to preserve pita bread contaminated with Penicillium verrucosum VTT D-01847, an OTA producer, in an active packaging system. Four different concentrations (8, 16, 33 and 50 mg/g) were tested. Mycelium formation, mycotoxin production, AITC absorbed by the food matrix, and volatilization kinetics were studied for each concentration. The results obtained were …

0106 biological sciencesOchratoxin AAntifungal AgentsFlourbreadPharmaceutical ScienceShelf life01 natural sciencesArticleAnalytical ChemistryAITClcsh:QD241-441chemistry.chemical_compoundIngredient0404 agricultural biotechnologylcsh:Organic chemistryIsothiocyanatesactive packaging010608 biotechnologyDrug DiscoveryPenicillium verrucosumHumansFood sciencePhysical and Theoretical ChemistryMycotoxinMycelium2. Zero hungerbiologyMyceliumChemistryOrganic ChemistryPenicilliumfood and beverages04 agricultural and veterinary sciencesbiology.organism_classificationAllyl isothiocyanate040401 food scienceOchratoxinsAspergillusFood Storageantifungal propertiesChemistry (miscellaneous)PenicilliumFood MicrobiologyFood PreservativesOTAMolecular Medicineshelf lifeMustard PlantMolecules
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