Search results for "activities"
showing 10 items of 3552 documents
Development and Validation of the Brief Music in Mood Regulation Scale (B-MMR)
2012
mood regulation has been shown to be among of the most important reasons for musical engagement, but there has been a lack of a concise measurement instrument for this behavior. The current study focused on developing and testing the Brief Music in Mood Regulation scale (B-MMR), a 21-item self-report instrument for assessing the use of seven different music-related mood-regulation strategies. Two survey studies (N = 1515 and N = 526) were conducted to first develop and then test and validate the instrument. The newly constructed scale showed adequate internal consistency reliabilities and correlated expectedly with measures of general emotion regulation and musical engagement. As a concise …
Data from: Microbiome symbionts and diet diversity incur costs on the immune system of insect larvae
2017
Communities of symbiotic microorganisms that colonize the gastrointestinal tract play an important role in food digestion and protection against opportunistic microbes. Diet diversity increases the number of symbionts in the intestines, a benefit that is considered to impose no cost for the host organism. However, less is known about the possible immunological investments that hosts have to make in order to control the infections caused by symbiont populations that increase due to diet diversity. By using taxonomical composition analysis of the 16S rRNA V3 region, we show that Enterococci are the dominating group of bacteria in the midgut of the larvae of the greater wax moth (Galleria mell…
Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases.
2008
The receptor for advanced glycation end products (RAGE) is a 55-kDa type I membrane glycoprotein of the immunoglobulin superfamily. Ligand-induced up-regulation of RAGE is involved in various pathophysiological processes, including late diabetic complications and Alzheimer disease. Application of recombinant soluble RAGE has been shown to block RAGE-mediated pathophysiological conditions. After expression of full-length RAGE in HEK cells we identified a 48-kDa soluble RAGE form (sRAGE) in the culture medium. This variant of RAGE is smaller than a 51-kDa soluble version derived from alternative splicing. The release of sRAGE can be induced by the phorbol ester PMA and the calcium ionophore c…
RAGE Mediates a Novel Proinflammatory Axis
1999
S100/calgranulin polypeptides are present at sites of inflammation, likely released by inflammatory cells targeted to such loci by a range of environmental cues. We report here that receptor for AGE (RAGE) is a central cell surface receptor for EN-RAGE (extracellular newly identified RAGE-binding protein) and related members of the S100/calgranulin superfamily. Interaction of EN-RAGEs with cellular RAGE on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Blockade of EN-RAGE/RAGE quenches delayed-type hypersensitivity and inflammatory colitis in murine models by arresting activation of central signaling pathw…
Competent youth in a "disorderly world": findings from an eighteen-nation study.
2012
Future- and school-related stressors are salient for adolescents from different regions of the world, and they cope with these stressors competently.
Mini-Review: Two Brothers in Crime – The Interplay of TRESK and TREK in Human Diseases
2021
Abstract TWIK-related spinal cord potassium (TRESK) and TWIK-related potassium (TREK) channels are both subfamilies of the two-pore domain potassium (K2P) channel group. Despite major structural, pharmacological, as well as biophysical differences, emerging data suggest that channels of these two subfamilies are functionally more closely related than previously assumed. Recent studies, for instance, indicate an assembling of TRESK and TREK subunits, leading to the formation of heterodimeric channels with different functional properties compared to homodimeric ones. Formation of tandems consisting of TRESK and TREK subunits might thus multiply the functional diversity of both TRESK and TREK …
Nuevos datos sobre la presencia de Terra Sigillata Hispánica en Britannia
2013
Nuevos datos sobre algunos fragmentos de TSH.
Photo-DHEA--a functional photoreactive dehydroepiandrosterone (DHEA) analog.
2011
Abstract The steroid hormone dehydroepiandrosterone (DHEA) has beneficial effects on vascular function, survival of neurons, and fatty acid metabolism. However, a specific receptor for DHEA has not been identified to date. Here, we describe the synthesis of a photoreactive DHEA derivative (Photo-DHEA). In Photo-DHEA, typical characteristics of DHEA are conserved: (i) a “planar” tetracyclic ring system with a Δ 5 double bond, (ii) a 3β-hydroxyl group, and (iii) a keto group at C17. In cell-based assays, Photo-DHEA showed the same properties as DHEA. We conclude that Photo-DHEA is suitable for radioiodination to yield a tool for the identification of the elusive DHEA receptor.
De Bibracte à Augustodunum : permanences et évolutions des activités manufacturières de l’époque gauloise à la fin du Haut-Empire
2007
L’importance de l’artisanat autunois et son développement jusqu’au iiie siècle prennent racine à Bibracte qui a su exploiter les ressources naturelles de son environnement et parfaire un savoir-faire local ayant survécu à la conquête. Les recherches sur ces activités manufacturières menées conjointement à Bibracte et à Autun nous offrent ainsi une opportunité d’étudier ces problématiques sur la durée. À Bibracte, puis à Autun, les artisans du métal sont omniprésents, mais d’autres métiers, aux témoins plus discrets, ont pu aussi êtres identifiés. Dans le cadre de cet article, nous présentons succinctement les lieux de production et un bilan des différents corps de métier. Enfin, nous évoquo…
Reduced performance difference between sexes in master mountain and city marathon running
2013
Matthias A Zingg,1 Beat Knechtle,1,2 Christoph Alexander Rüst,1 Thomas Rosemann,1 Romuald Lepers3 1Institute of General Practice and Health Services Research, University of Zurich, Zurich, Switzerland; 2Gesundheitszentrum St Gallen, St Gallen, Switzerland; 3INSERM U1093, Faculty of Sport Sciences, University of Burgundy, Dijon, France Background: The performance in master marathoners has been investigated in flat city marathons but not in mountain marathons. This study examined changes in the sex differences in performance across time in female and male master runners competing in a mountain marathon compared to a flat city marathon. Methods: The association between age and perform…