Search results for "adaptation"

Cooperation of Two mRNA-Binding Proteins Drives Metabolic Adaptation to Iron Deficiency

2008

Summary Iron (Fe) is an essential cofactor for a wide range of cellular processes. We have previously demonstrated in yeast that Cth2 is expressed during Fe deficiency and promotes degradation of a battery of mRNAs leading to reprogramming of Fe-dependent metabolism and Fe storage. We report here that the Cth2-homologous protein Cth1 is transiently expressed during Fe deprivation and participates in the response to Fe deficiency through the degradation of mRNAs primarily involved in mitochondrially localized activities including respiration and amino acid biosynthesis. In parallel, wild-type cells, but not cth1 Δ cth2 Δ cells, accumulate mRNAs encoding proteins that function in glucose impo…

Transcriptomic and Proteomic Approach for Understanding the Molecular Basis of Adaptation of Saccharomyces cerevisiae to Wine Fermentation

2006

ABSTRACT Throughout alcoholic fermentation, Saccharomyces cerevisiae cells have to cope with several stress conditions that could affect their growth and viability. In addition, the metabolic activity of yeast cells during this process leads to the production of secondary compounds that contribute to the organoleptic properties of the resulting wine. Commercial strains have been selected during the last decades for inoculation into the must to carry out the alcoholic fermentation on the basis of physiological traits, but little is known about the molecular basis of the fermentative behavior of these strains. In this work, we present the first transcriptomic and proteomic comparison between …

Adaptation to Low Salinity Promotes Genomic Divergence in Atlantic Cod (Gadus morhua L.).

2015

How genomic selection enables species to adapt to divergent environments is a fundamental question in ecology and evolution. We investigated the genomic signatures of local adaptation in Atlantic cod (Gadus morhua L.) along a natural salinity gradient, ranging from 35‰ in the North Sea to 7‰ within the Baltic Sea. By utilizing a 12 K SNPchip, we simultaneously assessed neutral and adaptive genetic divergence across the Atlantic cod genome. Combining outlier analyses with a landscape genomic approach, we identified a set of directionally selected loci that are strongly correlated with habitat differences in salinity, oxygen, and temperature. Our results show that discrete regions within the …

Transcultural adaptation and validation of a French version of the Physical Activity Scale for Individuals with Physical Disabilities (PASIPD-Fr).

2021

Validity and reliability of the Polish adaptation of the Health-Related Hardiness Scale – the first confirmatory factor analysis results for a common…

2020

BackgroundThe Health-Related Hardiness Scale (HRHS) developed by Pollock is one of the most widely used measures to assess the construct of hardiness in chronic diseases. However, the original structure of the scale has been investigated only with exploratory factor analysis, and there have been no studies investigating the structure of the scale using a confirmatory approach, so significant doubts about the validity of the scale could be raised.Participants and procedureA total of 450 participants took part in the study, with the majority suffering from chronic diseases. A Polish ver-sion of the HRHS, the Sense of Coherence questionnaire (SOC-29), the Resiliency Assessment Scale (SPP-25), …

Differential Evolution with Fitness Diversity Self-adaptation

2009

This chapter proposes the integration of fitness diversity adaptation techniques within the parameter setting of Differential Evolution (DE). The scale factor and crossover rate are encoded within each genotype and self-adaptively updated during the evolution by means of a probabilistic criterion which takes into account the diversity properties of the entire population. The population size is also adaptively controlled by means of a novel technique based on a measurement of the fitness diversity. An extensive experimental setup has been implemented by including multivariate problems and hard to solve fitness landscapes. A comparison of the performance has been conducted by considering both…

Study of Wine Producers’ Marketing Communication in Extreme Territories–Application of the AGIL Scheme to Wineries’ Website Features

2020

This study measures the communication ability of wineries in two extreme territories of Southern Italy, Mount Etna and the island of Pantelleria. The evaluation of four dimensions of web communication was carried out by the AGIL Scheme (i.e., adaptation, goal-attainment, integration, latent pattern maintenance). The study provides a generalizable model to be applied in other similar studies. Additionally, focus groups of experts were carried out. The method proved to be suitable to measure the communication effectiveness of wineries through websites. Extreme territories may add value to the wine, regardless of the brand. The heroic wines may become the symbol of these territories, helping e…

Adaptación transcultural y validación del contenido del Delaware School Climate SurveyStudent (DSCS-S) en Brasil

2016

El clima escolar evalúa las dimensiones: social, emocional, ética, académica y ambiental de la vida escolar, tales como normas, metas, valores, relaciones interpersonales, prácticas de enseñanza y aprendizaje y estructuras institucionales. El presente artículo pretende presentar el proceso de traducción, adaptación cultural y de investigación de la validación del contenido del instrumento de clima escolar del Delaware School Climate Survey-Student (DSCS-S) en Brasil, especialmente la investigación de la validad del contenido del instrumento a través del coeficiente de validad de contenido (CVC). El proceso consistió en etapas de traducción y retraducción, estudio piloto con público albo, ev…

Widespread secondary contact and new glacial refugia in the halophilic rotifer Brachionus plicatilis in the Iberian Peninsula.

2011

Small aquatic organisms harbour deep phylogeographic patterns and highly structured populations even at local scales. These patterns indicate restricted gene flow, despite these organisms' high dispersal abilities, and have been explained by a combination of (1) strong founder effects due to rapidly growing populations and very large population sizes, and (2) the development of diapausing egg banks and local adaptation, resulting in low effective gene flow, what is known as the Monopolization hypothesis. In this study, we build up on our understanding of the mitochondrial phylogeography of the halophilic rotifer Brachionus plicatilis in the Iberian Peninsula by both increasing the number of…

Predictors of decline in self-assessments of health among older people--a 5-year longitudinal study.

2001

Within the framework of the Evergreen project we examined how changes in several indicators of health and functioning and physical activity predicted a decline in self-assessments of health evaluated over a 5-year period in older people by two different measurements: self-rated health (SRH) and self-assessed change in health (SACH). The study group comprised all 75-year-old persons born in 1914 (N = 382) and living in Jyvaskyla, a town in central Finland. At baseline in 1989, 91.6%, and at follow-up 5 years later in 1994, 87.3% of those eligible participated in the interview and 77.2 and 71.3%, respectively, in the examinations in the study centre, focusing on different domains of health an…