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showing 10 items of 750 documents
Degradation of Antibiotic Vancomycin by UV Photolysis and Pulsed Corona Discharge Combined with Extrinsic Oxidants
2023
Antibiotics are the most frequently detected pharmaceuticals in the environment creating conditions for the development of resistant genes in bacteria. Degradation and mineralization of glycopeptide antibiotic vancomycin (VMN) were examined by UV photolysis, pulsed corona discharge (PCD), and their combinations with extrinsic oxidants, hydrogen peroxide (HP), peroxydisulfate (PDS), and peroxymonosulfate (PMS). Both combinations were effective in VMN degradation and faster at pH 11 than in acidic or neutral media. Combined with the UV photolysis, HP showed a higher oxidation rate than other oxidants, whereas PMS and PDS proved to be more efficient in combinations with PCD. In contrast to low…
Effect of ozone and hydrogen peroxide on off-flavor compounds and water quality in a recirculating aquaculture system
2022
The recirculating aquaculture system (RAS) is an ever-developing technology for producing fish with a low environmental impact. However, off-flavors can be a major problem in RAS fish production. Off-flavor compounds are of microbial origin and are accumulated in fish flesh. They typically cause a musty and earthy taste and odor, which consumers find unacceptable. Here we hypothesized that oxidizing compounds such as ozone (O3), hydrogen peroxide (H2O2), and their combinations, referred to as advanced oxidation processes (AOP)s, can remove or decrease these compounds in water and prevent their accumulation in fish. In this study, four different oxidative treatments (O3 low (0.4 mg O3 L−1), …
Quality of life of patients with advanced pancreatic cancer
2021
Pancreatic cancer is one of the most common malignancies with poor prognosis and high mortality. Advanced-stage disease at diagnosis and the dominant clinical symptoms significantly deteriorate the quality of life. The paper presents an analysis of the results of quality of life studies in patients with locally advanced and metastatic pancreatic cancer, as well as the relationship between therapeutic decisions and quality of life indicators. It has been shown that the initial assessment of life quality can have prognostic value.Appropriate symptomatic treatment of patients with advanced pancreatic cancer improves the quality of life, increases the compliance and prolongs survival. The asses…
Tietoturvan ihmiselementti : sosiaalinen manipulointi
2017
Tämän tutkielman aiheena on sosiaalinen manipulointi, tietoturvan ihmiselementti ja sen huomioon ottaminen ja hyökkäysten ehkäiseminen yrityksen tai organisaation tietoturvassa. Sosiaalisella manipuloinnilla tarkoitetaan tutkielman kontekstissa tietojärjestelmän käyttäjiin kohdistuvaa manipulointia, jonka tavoitteena on informaation keruu tai tietojärjestelmään murtautuminen. Aihetta on tärkeää tutkia, sillä useat tietoturva-asiantuntijat ovat yhtä mieltä siitä, että merkittävin tietojärjestelmän tietoturvauhka on sen käyttäjät ja heidän tietoturvallisuuden näkökulmasta tekemät inhimilliset erehdykset. Sosiaalinen manipulointi kohdistuu juuri tähän tietoturvan heikkouteen. Tutkielman tuloks…
Cell therapy medicinal product regulatory framework in Europe and its application for MSC-based therapy development
2012
Advanced therapy medicinal products (ATMPs), including cell therapy products, form a new class of medicines in the European Union. Since the ATMPs are at the forefront of scientific innovation in medicine, specific regulatory framework has been developed for these medicines and implemented from 2009. The Committee for Advanced Therapies (CAT) has been established at the European Medicines Agency (EMA) for centralized classification, certification and evaluation procedures, and other ATMP-related tasks. Guidance documents, initiatives, and interaction platforms are available to make the new framework more accessible for small- and medium-sized enterprises, academia, hospitals, and foundation…
Advanced chronic kidney disease. Association between anxiety, depression and resilience
2019
Resumen Introducción: el padecimiento de la enfermedad renal crónica avanzada (ERCA) se asocia con una mayor probabilidad de padecer sintomatología depresiva y ansiosa. No obstante, la resiliencia puede amortiguar estos efectos. El objetivo general fue valorar la sintomatología ansiosa, depresiva y la resiliencia de los pacientes con ERCA. Métodos: 70 pacientes (80 % varones), con edades entre 38-88 años (M=68,88; DT= 9,98) fueron evaluados mediante la Escala Hospitalaria de Ansiedad y Depresión y la de Resiliencia de Connor Davidson. Se realizaron análisis descriptivos, pruebas t, d de Cohen y correlaciones de Pearson. Resultados: un 41,79 % presentó sintomatología ansiosa y un 25,38 % dep…
Nursing competence in municipal in-patient acute care in Norway: a cross-sectional study
2020
Abstract Background The primary health care services are becoming increasingly complex, which presents challenges for the municipal nursing services. In Norway, municipal in-patient acute care (MipAC) has been introduced in all municipalities, and the competence at the services has been questioned. Few studies have examined the nursing services in the units. This study aims to get an overview of the nursing competence in those units across geographical regions, and different groups of organisation and localisation. Methods A cross-sectional study was conducted, and an ad hoc questionnaire was distributed to first-line leaders in all the MipAC units in Norway. Data were collected in the peri…
Amazon's initiative transforming a non-contact society : Digital disruption leads the way to stakeholder capitalization
2021
Contrary to the decisive role of R&D centered on information and communication technology (ICT) in the digital economy, its excessive expansion has resulted in declining productivity due to the two-faced nature of ICT. Consequently, the novel concept emerges of innovation that maintains sustainable growth by harnessing the vigor of soft innovation resources (SIRs). Pioneering endeavors can be observed at the forefront of the global ICT leaders. World R&D leader Amazon has been harnessing the power of users that seek SIRs. This functions as a virtuous cycle, leading to the transformation of R&D by fusing a unique R&D system with a sophisticated financing system. With this orchestration, Amaz…
A New Perspective on the Textile and Apparel Industry in the Digital Transformation Era
2022
The textile and apparel (fashion) industry has been influenced by developments in societal socio-cultural and economic structures. Due to a change in people’s preferences from economic functionality to supra-functionality beyond economic value, the fashion industry is at the forefront of digitalization. The growing digitalization in the fashion industry corresponds to digital fashion, which can satisfy the rapid shift in consumers’ preferences. This paper explores the evolving con-cept of innovations in digital fashion in the textile and apparel industry. Specifically, it centers on the evaluation of Amazon’s digital fashion initiatives, which have made the platform the Un…
Clinical Assessment of the Effects of Low-Level Laser Therapy on Coronally Advanced Flap Procedure in the Management of Isolated Gingival Recession
2022
The aim of this randomized, controlled split-mouth clinical trial was to assess the effect of LLLT on wound healing after modified coronally advanced flap (MCAF) procedure for treatment of isolated recession-type defects. Fifteen patients with isolated bilaterally symmetrical gingival recessions (Miller’s Class I or Class II, or a combination of both) were enrolled in this study. After a modified, coronally advanced flap technique was implemented, a diode laser (810 nm) with a power of 120 mW irradiated the inner surface of the flap and the outer surface of the flap (low-level laser therapy—LLLT) after suturing for 5 min. This was repeated for the following four consecutive days…