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Minimally Invasive Approaches in Locally Advanced Cervical Cancer Patients Undergoing Radical Surgery After Chemoradiotherapy: A Propensity Score Ana…

2020

Abstract Purpose Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical surgery (MI-RS) compared with open radical surgery (O-RS). Patients and Methods Data for stage IB2–IVA cervical cancer patients managed by CT/RT and RS were retrospectively analyzed. Results Beginning with 686 patients, propensity score matching resulted in 462 cases (231 per group), balanced for FIGO stage, lymph node status, histotype, tumor grade, and clinical respons…

medicine.medical_specialtymedicine.medical_treatmentConcomitant Chemoradiation Neoadjuvant Chemotherapy Phase III Hysterectomy Radiation Therapy WomenUterine Cervical NeoplasmsHysterectomyDisease-Free Survival03 medical and health sciences0302 clinical medicinePhase IIIlocally advanced cervical cancer (LACC)locally advanced cervical cancerHumansMedicineWomenChemoradiotherapy; Disease-Free Survival; Female; Humans; Hysterectomy; Neoadjuvant Therapy; Neoplasm Recurrence Local; Neoplasm Staging; Propensity Score; Retrospective Studies; Uterine Cervical Neoplasms030212 general & internal medicineStage (cooking)Radical surgeryPropensity ScoreNeoadjuvant therapyNeoplasm StagingRetrospective StudiesCervical cancerHysterectomyRadiationbusiness.industrylocally advanced cervical cancer surgeryNeoadjuvant ChemotherapyRetrospective cohort studyChemoradiotherapyGynecologic Oncologymedicine.diseaseNeoadjuvant TherapySurgeryRadiation therapySettore MED/40 - GINECOLOGIA E OSTETRICIANeoplasm RecurrenceLocalOncology030220 oncology & carcinogenesisConcomitant ChemoradiationFemaleSurgeryTherapyNeoplasm Recurrence LocalbusinessChemoradiotherapy
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Peritoneal carcinomatosis index as a predictor of diaphragmatic involvement in stage III and IV ovarian cancer

2018

Antoni Llueca,1–3 Anna Serra,1–3 José Luis Herraiz,2 Isabel Rivadulla,1,4 Luis Gomez-Quiles,1,4 Juan Gilabert-Estelles,5,6 Javier Escrig1,3,4On behalf of the MUAPOS (Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery) working group 1Multidisciplinary Unit of Abdominal Pelvic Oncology Surgery (MUAPOS), University General Hospital of Castellón, Castellón, Spain; 2Department of Obstetrics and Gynecology, University General Hospital of Castellón, Castellón, Spain; 3Department of Medicine, Universitat Jaume I, Castellón, Spain; 4Department of General Surgery, University General Hospital of Castell&…

medicine.medical_specialtyperitoneal cancer indexdiaphragmatic involvementDiaphragmatic breathingcarcinomatosisOncoTargets and Therapy030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMedicinePeritoneal Carcinomatosis IndexPharmacology (medical)Stage (cooking)CàncerSurvival rateOriginal ResearchAdvanced ovarian canceradvanced ovarian cancerbusiness.industryupper abdominal surgerymedicine.diseaseSurgeryOncology030220 oncology & carcinogenesisConventional PCIPeritoneal Cancer IndexbusinessOvarian cancerOncoTargets and therapy
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Population Properties of Compact Objects from the Second LIGO-Virgo Gravitational-Wave Transient Catalog

2021

Abbott, R., et al. (LIGO and Virgo Collaboration)

neutron star: binary010504 meteorology & atmospheric sciencesAstronomyAstrophysicsspin01 natural sciencesGeneral Relativity and Quantum Cosmologymass spectrumMassive starsAGN DISCSLIGO010303 astronomy & astrophysicsQCFocus on Gravitational-wave Astrophysics from the Second LIGO-Virgo Transient CatalogQBSettore FIS/01High Energy Astrophysical Phenomena (astro-ph.HE)astro-ph.HEPhysicseducation.field_of_studyMass distributionSettore FIS/05Astrophysical black holesStellar mass black holesBINARY MERGERSJustice and Strong InstitutionsCompact Binary Populations Gravitational Waves GW Transient Cataloggravitational wavesAStrophysical black holesPhysical Sciences[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]Astrophysics - High Energy Astrophysical PhenomenaYOUNG STAR-CLUSTERSEFFECTIVE SPIN DISTRIBUTIONmass: asymmetryBLACK-HOLE MERGERSSDG 16 - PeaceexceptionalNEUTRON-STARSgr-qcPopulationFOS: Physical sciencesgapContext (language use)General Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic AstrophysicsPUBLIC ADVANCED LIGOGravitational waves; Astrophysical black holes; Stellar mass black holes; Massive stars; Compact objects; Bayesian statisticsAstronomy & AstrophysicsBayesian statisticsangular momentumGravitational wavesSettore FIS/05 - Astronomia e Astrofisicaprecession0103 physical sciencesstructureeducationcaptureCompact objectsAstrophysics::Galaxy AstrophysicsSTFC0105 earth and related environmental sciencesMASS-DISTRIBUTIONBLACK-HOLE MERGERS; YOUNG STAR-CLUSTERS;EFFECTIVE SPIN DISTRIBUTIONHIERARCHICAL MERGERSScience & TechnologyStar formationGravitational waveSDG 16 - Peace Justice and Strong Institutionsgravitational radiationRCUKAstronomy and Astrophysicsredshiftbinary: compact/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsDewey Decimal Classification::500 | Naturwissenschaften::520 | Astronomie KartographieLIGORedshiftNeutron starVIRGOblack hole: binaryGravitational Waves Compact Binaries[SDU]Sciences of the Universe [physics]Space and Planetary Scienceddc:520[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Compact BinariesDYNAMICAL FORMATION
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GW170817: Observation of Gravitational Waves from a Binary Neutron Star Inspiral

2017

On August 17, 2017 at 12-41:04 UTC the Advanced LIGO and Advanced Virgo gravitational-wave detectors made their first observation of a binary neutron star inspiral. The signal, GW170817, was detected with a combined signal-to-noise ratio of 32.4 and a false-alarm-rate estimate of less than one per 8.0×104 years. We infer the component masses of the binary to be between 0.86 and 2.26 M, in agreement with masses of known neutron stars. Restricting the component spins to the range inferred in binary neutron stars, we find the component masses to be in the range 1.17-1.60 M, with the total mass of the system 2.74-0.01+0.04M. The source was localized within a sky region of 28 deg2 (90% probabili…

neutron star: binary[ PHYS.ASTR ] Physics [physics]/Astrophysics [astro-ph]X-ray binaryADVANCED LIGOAstrophysicsKilonovagravitational waves; LIGO; binary neutron star inspiralspin01 natural sciencesLIGOGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)QCQBHigh Energy Astrophysical Phenomena (astro-ph.HE)Electromagnetic observationsGravitational-wave signals3100 General Physics and AstronomyPoint MassesAstrophysics - High Energy Astrophysical PhenomenaBlack-Hole MergersBinary neutron starsBlack HolesX-ray bursterCoalescing BinariesAstrophysics::High Energy Astrophysical Phenomena10192 Physics InstituteGeneral Relativity and Quantum Cosmology (gr-qc)Gravity wavesGravitational wavesNeutron starsPhysics and Astronomy (all)ddc:530Electromagnetic spectraNeutrons010308 nuclear & particles physicsVirgoGamma raysAstronomyRCUKVIRGOelectromagneticgravitational radiation: emissionStellar black holeGamma-ray burst[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Compact Binariesbinary: masscosmological modelAstronomyGeneral Physics and AstronomyAstrophysicsneutron starsGamma ray burstsGeneral Relativity and Quantum CosmologyGravitational wave detectorsUniverseDENSE MATTER010303 astronomy & astrophysicsastro-ph.HEPhysicsSignal to noise ratioSettore FIS/01 - Fisica SperimentaleGravitational effectsFalse alarm rateEQUATION-OF-STATEMergers and acquisitionsgravitational waves[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]530 PhysicsMERGERSGeneral Relativity and Quantum Cosmology; General Relativity and Quantum Cosmology; astro-ph.HEFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic Astrophysicsgamma ray: burstgravitational radiation: direct detectionMerging[ PHYS.GRQC ] Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]GAMMA-RAY BURSTLIGO (Observatory)binary: coalescenceGravitational waves neutron stars gamma-ray burst LIGO Virgo0103 physical sciencesGW151226MASSESSTFCAstrophysics::Galaxy AstrophysicsPhysiqueGravitational wavegravitational radiationPULSARgravitational radiation detectorNeutron starPhysics and AstronomygravitationRADIATIONDewey Decimal Classification::500 | Naturwissenschaften::530 | Physikbinary neutron star inspiralSignal detectionPHYS REV LETT PHYSICAL REVIEW LETTERS
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Open University and Zero-Advanced Students - Who the Students Are and Why They Don't Progress?

2020

In recent decades, the talk of lifelong and continuous learning has become an internationally prevailing trend. Lifelong learning has many meanings depending on the interests and the determinants. On the other hand, lifelong learning is understood in the context of adult education as the OECD's contribution to market-liberal social and economic governance. In this case, the main actor is the individual with responsibilities and duties to ensure social competitiveness. On the other hand, lifelong learning is defined by adult education, cultural democracy, narrowing educational disparities and cultural equality. In the ethos of lifelong learning and in the spirit of continuous education, many…

opintomenestyselinikäinen oppiminenComputingMilieux_COMPUTERSANDEDUCATIONopintosuorituksetopen universityzero-advanced student.avoin yliopistoadult studentaikuisopiskelu
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De participació local. Una proposta metodològica desde la investigació-acció-participativa

2018

Citizen participation is an increasingly prevalent term in our society. In the process of deployment in the municipal area, progressively local corporations make efforts to innovate practices and develop experiences of citizen participation in defining policies and public affairs, and allocating budgets. While innovation has been advanced with regard to the tools and mechanisms to be used to promote participation, many of the initiatives and experiences have focused more on the implementation of the vote than in the different social processes inherent in the participation. Moreover, we are faced with the absence of a methodological guide that allows approaching a project or strategic plan o…

pl aSimó-Nogueraparticipatory research-action:SOCIOLOGÍA [UNESCO]Carles-Xavier Citizen participation is an increasingly prevalent term in our society. In the process of deployment in the municipal areawe are faced with the absence of a methodological guide that allows approaching a project or strategic plan of participation that organizes the interventions of the problems of the citizens. Through a methodology based on participatory research-actioninvestigació-acció participativaand allocating budgets. While innovation has been advanced with regard to the tools and mechanisms to be used to promote participationprogressively local corporations make efforts to innovate practices and develop experiences of citizen participation in defining policies and public affairsmany of the initiatives and experiences have focused more on the implementation of the vote than in the different social processes inherent in the participation. MoreoverEnricUNESCO::SOCIOLOGÍAthis article tries tentatively to outline the lines of this plan. participacióparticipation1137-7038 8537 Arxius de sociologia 493757 2018 38 6508349 De participació local. Una proposta metodològica desde la investigació-acció-participativa Sigalat Signesplan. 107 122
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Oscillation of Second-Order Neutral Differential Equations

2013

Author's version of an article in the journal: Funkcialaj Ekvacioj. Also available from the publisher at: http://www.math.kobe-u.ac.jp/~fe/ We study oscillatory behavior of a class of second-order neutral differential equations relating oscillation of these equations to existence of positive solutions to associated first-order functional differential inequalities. Our assumptions allow applications to differential equations with both delayed and advanced arguments, and not only. New theorems complement and improve a number of results reported in the literature. Two illustrative examples are provided.

positive solutionsAlgebra and Number TheoryOscillationMathematical analysisdelayed argumentsoscillationcomparisonControl theoryOrder (group theory)VDP::Matematikk og Naturvitenskap: 400::Matematikk: 410::Analyse: 411Geometry and Topologyadvanced argumentsNeutral differential equationsneutral differential equationsAnalysisMathematicsFunkcialaj Ekvacioj
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Uncertainty evaluation in load flow analysis: real MV distribution networks case studies

2018

This work investigates the measurement uncertainty impact on load flow analysis in medium voltage (MV) distribution networks. The considered algorithm is a simplified load flow algorithm (LFA), developed by authors, which is based on the load power measurements at each secondary substation and one voltage measurement at the slack bus (i.e. the voltage at the MV bus bars of the primary substation). In the viewpoint of a real implementation, to reduce monitoring system costs, the LFA makes use of low voltage (LV) load power measurements for all the substations except those of MV users, where MV transducers are usually already installed. The uncertainties on LFA input quantities (load powers a…

power system monitoringPower system measurementpower quality analyzers (PQA)load flow analysismart gridadvanced metering infrastructure (AMI)Settore ING-INF/07 - Misure Elettriche E Elettroniche
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Organizational identity and competition : a study of US semiconductor industry

2017

Organisationaalinen identiteetti ja kilpailu : tutkielma puolijohdeteollisuudesta. Tutkimuksen​ ​tehtävänä​ ​on​ ​selvittää,​ ​miten​ ​kaksi​ ​samalla​ ​puolijohdesektorilla​ ​kilpailevaa yritystä,​ ​Intel​ ​Corporation​ ​ja​ ​Advanced​ ​Micro​ ​Devices,​ ​kuvailee​ ​itseänsä​ ​ja​ ​kenttäänsä suhteessa​ ​kilpailijoihinsa​ ​ja​ ​siten​ ​rakentaa​ ​ja​ ​ylläpitää​ ​organisationaalista​ ​identiteettiään. Tutkimuksen​ ​teoreettisena​ ​näkökulmana​ ​on​ ​tarkastella​ ​markkinoita​ ​sosiaalisesti​ ​rakentuneena kenttänä​ ​jota​ ​kilpailu​ ​ylläpitää.​ ​Analyysimenetelmänä​ ​on​ ​käytetty​ ​koneoppivaa​ ​tekstin mallinnusmenetelmää​ ​nimeltä​ ​Latentti​ ​Dirichlet​ ​Allokaatio​ ​(LDA),​ ​jolla​ ​…

sosiologiaLatent Dirichlet Allocation (LDA)Advanced​ ​Micro​ ​Devicesmarkkinat (taloustiede)organisaatiotidentiteettiIntelkilpailuteollisuusyritykset
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TP53 mutations and S-phase fraction but not DNA-ploidy are independent prognostic indicators in laryngeal squamous cell carcinoma

2005

To prospectively evaluate the prognostic significance of TP53, H-, K-, and N-Ras mutations, DNA-ploidy and S-phase fraction (SPF) in patients affected by locally advanced laryngeal squamous cell carcinoma (LSCC). Eight-one patients (median follow-up was 71 months) who underwent resective surgery for primary operable locally advanced LSCC were analyzed. Tumor DNA was screened for mutational analysis by PCR/SSCP and sequencing. DNA-ploidy and SPF were performed by flow cytometric analyses. Thirty-six patients (44%) had, at least, a mutation in the TP53 gene. Of them, 22% (8/36) had double mutations and 3% (1/36) had triple mutations. In total, 46 TP53 mutations were observed. The majority (41…

squamous cell carcinomasingle strand conformation polymorphismPrognosipolymerase chain reactionDNA Mutational AnalysisEMTREE drug terms: protein p53 EMTREE medical terms: advanced cancerS PhaseDNA Mutational AnalysiHumansprotein p53 advanced cancer; article; cell cycle S phase; DNA content; exon; flow cytometry; follow up; gene; gene mutation; genetic analysis; histopathology; human; human tissue; larynx carcinoma; multivariate analysis; ploidy; polymerase chain reaction; priority journal; prospective study; single strand conformation polymorphism; squamous cell carcinoma; tp53 gene Carcinoma Squamous Cell; DNA Mutational Analysis; DNA Neoplasm; Genes ras; Humans; Laryngeal Neoplasms; Mutation; Ploidies; Polymorphism Single-Stranded Conformational; Prognosis; S Phase; Survival Rate; Tumor Suppressor Protein p53 [EMTREE drug terms]follow uplarynx carcinomatp53 gene MeSH: Carcinoma Squamous Cellexongene mutationhumanmultivariate analysigeneLaryngeal NeoplasmsPolymorphism Single-Stranded ConformationalLaryngeal NeoplasmPloidiesflow cytometryarticleploidyDNA NeoplasmPrognosisGenes rahuman tissueSurvival RateGenes rascell cycle S phasepriority journalDNA contentgenetic analysiMutationCarcinoma Squamous CellhistopathologyTumor Suppressor Protein p53Ploidieprospective study
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