Search results for "age factors"

showing 10 items of 1176 documents

Screening for Hypochondriasis With the Illness Attitude Scales

2010

The Illness Attitude Scales (IAS; Kellner, 1986, 1987) may prove highly useful for the screening of hypochondriasis. We expected the IAS subscales to be equally as effective as the 7-item short version of the Whiteley Index (Whiteley-7; Fink et al., 1999), which has previously been shown to be useful in screening for somatoform disorders. We investigated participants of a German population (n = 1,575) and 61 patients with the Diagnostic and Statistical Manual of Mental Disorders (4th ed. [DSM-IV]; American Psychiatric Association, 1994) diagnosis of hypochondriasis. The Bodily Preoccupations (BP) subscale showed high sensitivity (.92) and specificity (.90) as well as demonstrating convergen…

AdultMalemedicine.medical_specialtyAdolescentPersonality InventoryPsychometricsValidation testHealth Toxicology and MutagenesisTest validitySensitivity and SpecificityYoung AdultSex FactorsArts and Humanities (miscellaneous)German populationGermanymedicineHumansPsychiatryAgedAged 80 and overPsychiatric Status Rating ScalesAge FactorsDiscriminant validityReproducibility of ResultsMiddle AgedHypochondriasisClinical PsychologyConvergent validityPsychiatric status rating scalesEducational StatusFemalePersonality Assessment InventoryPsychologyJournal of Personality Assessment
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Handling forces for the use of different inhaler devices.

2019

Abstract Age and comorbidities can impact on the success of handling an inhaler. In this pilot study, we assessed finger strength in 62 participants (aged 5–17 years [n = 20], 18–65 years [n = 22] and > 65 years [n = 20]) by using different types of inhalers with integrated sensors (Respimat®, Breezhaler®, Aerolizer®, Genuair®, Diskus®, Ellipta®, HandiHaler®, Turbohaler® and a pressurized metered-dose inhaler [Atrovent®]). Parameters under investigation included the spontaneous and maximum achievable force and torque required to operate devices. Satisfaction with individual inhalers, and the relationship between satisfaction and strength, were also assessed. There was a marked difference in…

AdultMalemedicine.medical_specialtyAdolescentPharmaceutical SciencePilot Projects02 engineering and technology030226 pharmacology & pharmacyFingers03 medical and health sciencesYoung Adult0302 clinical medicineAge groupsRheumatic DiseasesAdministration InhalationMedicineHumansChildAgedAged 80 and overHand Strengthbusiness.industryInhalerNebulizers and VaporizersHealthy subjectsAge FactorsRheumatic diseaseEquipment DesignMiddle Aged021001 nanoscience & nanotechnologyPatient preferenceDry-powder inhalerPatient SatisfactionCase-Control StudiesChild PreschoolPhysical therapyFemale0210 nano-technologybusinessInternational journal of pharmaceutics
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Mortality in affective disorders.

2001

Abstract Background : To investigate the mortality rates in affective disorders due to unnatural and natural causes with respect to illness subtype and social–demographic features. Methods : Mortality data were determined from a prospective study of 354 outpatients with affective disorders during a follow-up period of 5 years. Death from natural and unnatural causes was compared to sex- and age-specific expectations in the general population. Standardized mortality rates (SMR) in diagnostic subgroups and the influence of social–demographic features were investigated. Results : The observed 30 deaths represented nearly three times (SMR, 2.9) the number expected on the basis of age- and sex-s…

AdultMalemedicine.medical_specialtyAdolescentPopulationPoison controlSex FactorsCause of DeathGermanyInjury preventionmedicineHumansBipolar disorderProspective StudieseducationPsychiatryChildDepression (differential diagnoses)Cause of deathAgedPsychiatric Status Rating Scaleseducation.field_of_studyMood DisordersMortality rateAge FactorsMiddle Agedmedicine.diseasePsychiatry and Mental healthClinical PsychologySuicideCross-Sectional StudiesSocioeconomic FactorsAccidentsFemalemedicine.symptomPsychologyHomicideManiaFollow-Up StudiesJournal of affective disorders
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Predictors of stigmatizing attitudes towards people with mental disorders in a general population in Finland

2010

For planning effective and well-targeted initiatives to reduce stigma, we need to identify which factors are associated with stigmatizing of people with mental disorders.This study examined how well a combination of variables predicts stigmatizing attitudes and discrimination in a general population.A survey questionnaire was sent to 10,000 persons aged 15-80 years residing in western Finland. Attitudes were measured using a scale consisting of negative stereotypes about people with depression and stereotypical beliefs connected with mental problems, while discrimination was measured by a social distance scale. Predictors included demographic variables, mental health resources, personal exp…

AdultMalemedicine.medical_specialtyAdolescentSocial StigmaPopulationPsychological interventionStigma (botany)Young AdultSex FactorsSurveys and QuestionnairesBogardus social distance scalemedicineHumansPsychiatryeducationFinlandInternal-External Controlta515Depression (differential diagnoses)AgedAged 80 and overDepressive DisorderStereotypingeducation.field_of_studyData CollectionMental DisordersAge FactorsSocial SupportPsychological distressMiddle AgedMental healthPsychiatry and Mental healthPsychological DistancePublic OpinionScale (social sciences)FemalePsychologyPrejudiceClinical psychologyNordic Journal of Psychiatry
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Personality and perception of stigma in psychiatric patients with depressive disorders

2010

Objective The study seeks to determine the relationships between neuroticism and extroversion, on the one side, and the perception of various dimensions of social stigma, on the other, in psychiatric in-patients with depressive disorders, such as depressive episodes, or mood and anxiety disorders with the presence of depressive symptoms. Material and methods A total of 72 patients were examined in the study. Twenty four of them (F/M - 12/12; age range 42-65 years) were used for assessing the reliability of a depression stigma questionnaire (DSQ) created specifically for this study. The remaining 48 patients (F/M - 31/17; age range 17-74 years) were then surveyed with the DSQ and other psych…

AdultMalemedicine.medical_specialtyAdolescentSocial stigmamedia_common.quotation_subjectSurveys and QuestionnairesmedicineHumansPersonalityneuroticismPsychiatryAgedmedia_commonDepressive DisorderStereotypingExtraversion and introversionResearchAge FactorsGeneral MedicineMiddle AgedMental illnessmedicine.diseasemental illnessNeuroticismStigma (anatomy)MoodstigmapersonalitydepressionextroversionEducational StatusAnxietyFemalemedicine.symptomPsychologyConfidentialityEuropean Journal of Medical Research
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Age and Grip Strength Predict Hand Dexterity in Adults.

2015

In the scientific literature, there is much evidence of a relationship between age and dexterity,\ud where increased age is related to slower, less nimble and less smooth, less coordinated\ud and less controlled performances. While some suggest that the relationship is a direct consequence\ud of reduced muscle strength associated to increased age, there is a lack of research\ud that has systematically investigated the relationships between age, strength and\ud hand dexterity. Therefore, the aim of this study was to examine the associations between\ud age, grip strength and dexterity. 107 adults (range 18-93 years) completed a series of hand\ud dexterity tasks (i.e. steadiness, line tracking…

AdultMalemedicine.medical_specialtyAdolescentStrength traininglcsh:MedicineQ1Grip strengthYoung AdultPhysical medicine and rehabilitationHand strengthComputer softwaremedicineHumansDirect consequencelcsh:ScienceMotor skillAgedAged 80 and overMultidisciplinaryMuscle WeaknessHand Strengthlcsh:RAge FactorsMuscle weaknessMiddle AgedHandQPMotor SkillsMuscle strengthPhysical therapylcsh:QFemalemedicine.symptomPsychologyResearch Article
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The Effect of Age, Sex, Smoking and Co-Medication on Serum Levels of Venlafaxine and O-Desmethylvenlafaxine under Naturalistic Conditions

2012

Venlafaxine (VEN) is a modern antidepressant which exerts both serotonin and norepinephrine reuptake inhibition. In this study we examined the influence of age, sex, smoking, and co-medication on serum levels of VEN and its metabolite O-desmethylvenlafaxine (ODVEN) in patients treated with VEN under naturalistic conditions.We retrospectively evaluated 478 TDM analyses of VEN requested in the Pychiatric University Hospitals of Mainz, Regensburg, and Würzburg. The determination of serum levels was performed by virtually identical chromatographic methods in the TDM laboratories of the participating hospitals.Serum levels varied widely on each dose level. Women had about 30% higher dose-correct…

AdultMalemedicine.medical_specialtyAdolescentVenlafaxine HydrochlorideVenlafaxinePharmacokineticsDesvenlafaxine SuccinateInternal medicinemedicineHumansPharmacology (medical)DosingAgedRetrospective StudiesAged 80 and overSex Characteristicsbusiness.industrySmokingAge FactorsVenlafaxine HydrochlorideRetrospective cohort studyGeneral MedicineMiddle AgedCyclohexanolsPsychiatry and Mental healthAnesthesiaVenAntidepressive Agents Second-GenerationAntidepressantDrug Therapy CombinationFemaleDrug Monitoringbusinessmedicine.drugSex characteristicsPharmacopsychiatry
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Vocal fold strain and vocal pitch in singing:Radiographic observations of singers and nonsingers

1998

Summary The relationship between vocal fold strain and vocal pitch in singersand nonsingers singing a rising pitch series has been indirectly investigated by means of lateral radiographs. Nonsingers tend to exhibit more strain than singers. To standardize the degree of strain, an index of strain per semitone is proposed. The semitone strain indicates the average amount of strain per 1 semitone of pitch increase or decrease. The index has been shown to be affected by several factors: gender, singing training, singing technique, voice class, age, and status of muscle function. Observations suggest that similar groups of individuals occupy different positions on the stress-strain curve, indica…

AdultMalemedicine.medical_specialtyAdolescentVoice QualitySpeech recognitionThyroid GlandVocal CordsAudiologySemitoneSpeech and HearingSex FactorsPhonationotorhinolaryngologic diseasesmedicineHumansSpeechAgedMathematicsAge FactorsMiddle AgedLPN and LVNhumanitiesVocal pitchRadiographyOtorhinolaryngologyVoiceFemaleSingingpsychological phenomena and processesJournal of Voice
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Global and regional cortical thinning in first-episode psychosis patients: relationships with clinical and cognitive features

2010

BackgroundThe thickness of the cortical mantle is a sensitive measure for identifying alterations in cortical structure. We aimed to explore whether first episode schizophrenia patients already show a significant cortical thinning and whether cortical thickness anomalies may significantly influence clinical and cognitive features.MethodWe investigated regional changes in cortical thickness in a large and heterogeneous sample of schizophrenia spectrum patients (n=142) at their first break of the illness and healthy controls (n=83). Magnetic resonance imaging brain scans (1.5 T) were obtained and images were analyzed by using brains2. The contribution of sociodemographic, cognitive and clinic…

AdultMalemedicine.medical_specialtyAdolescentbrainBrain mappingArticleYoung AdultCognitionCortex (anatomy)Internal medicineImage Processing Computer-AssistedmedicineHumansApplied PsychologyCerebral CortexPsychiatric Status Rating ScalesAnalysis of VarianceBrain Mappingmedicine.diagnostic_testAge FactorsMagnetic resonance imagingMiddle Agedcortical thicknessmedicine.diseaseMagnetic Resonance ImagingendophenotypeschizophreniaPsychiatry and Mental healthmedicine.anatomical_structureCerebral cortexSchizophreniaEndophenotypeCardiologyFemaleAnalysis of varianceAge of onsetPsychologyNeuroscienceMRIPsychological Medicine
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Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients.

2003

Experimental and clinical studies give evidence for breakdown of membrane phospholipids during neurodegeneration. In the present study, we measured the levels of glycerophosphocholine (GPCh), phosphocholine (PCh), and choline, that is, water-soluble metabolites of phosphatidylcholine (PtdCho), in human cerebrospinal fluid (CSF). Among 30 cognitively normal patients the average CSF levels of GPCh, phosphocholine and choline were 3.64, 1.28, and 1.93 microM, respectively; metabolite levels did not change with increasing age. When compared with age-matched controls, patients with Alzheimer's disease had elevated levels of all choline metabolites: GPCh was significantly increased by 76% (P<0.01…

AdultMalemedicine.medical_specialtyAgingAdolescentMetabolitePhosphorylcholineCholinechemistry.chemical_compoundPhospholipase A2Cerebrospinal fluidAlzheimer DiseasePhosphatidylcholineInternal medicinemedicineCholineHumansVascular dementiaPhosphocholineAgedAged 80 and overbiologyPhosphorylcholineGeneral NeuroscienceDementia VascularAge FactorsMiddle Agedmedicine.diseaseGlycerylphosphorylcholineEndocrinologychemistryImmunologybiology.proteinFemaleNeurology (clinical)Geriatrics and GerontologyBiomarkersDevelopmental BiologyNeurobiology of aging
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