Search results for "aggregate"

Actinopathies and Myosinopathies

2009

The currently recognized two forms of "anabolic" protein aggregate myopathies, that is, defects in development, maturation and final formation of respective actin and myosin filaments encompass actinopathies and myosinopathies. The former are marked by mutations in the ACTA1 gene, largely of the de novo type. Aggregates of actin filaments are deposited within muscle fibers. Early clinical onset is often congenital; most patients run a rapidly progressive course and die during their first 2 years of life. Myosinopathies or myosin storage myopathies also commence in childhood, but show a much more protracted course owing to mutations in the myosin heavy chain gene MYH7. Protein aggregation co…

Price Impact Function of a Single Transaction

2004

Although supply and demand are perhaps the most fundamental concepts in economics, finding any general form for their behavior has proved to be elusive. Here we discuss our recent findings [1] on the price impact function empirically detected in the New York Stock Exchange (NYSE). Our study builds on earlier studies of how trading affects prices [2, 3, 4, 5, 6, 7, 8, 9, 10, 11]. In particular, we look at the short term response to a single trade. This is done by using huge amounts of data and by measuring the market activity in units of transactions rather than seconds, so that we can more naturally aggregate data for many different stocks. This allows us to find regularities in the respons…

From Waste to Resource – Utilising Residue from Ready-Made Concrete as New Aggregate

2021

Abstract A new admixture is available, to reduce the sludge produced from the cleansing of production and transportation equipment in the fresh concrete industry. The result is agglomerations of hardening concrete, that might be utilised for aggregate. Utilisation depends on adequate properties. This paper reports from investigations on the physical and mechanical properties of the aggregate and discussions on the performance relative to natural and recycled aggregates and towards requirements for utilisation. The findings indicate substantial potential for utilisation, supporting the reduction of waste for deposit and development of the concrete industry towards a circular economy.

Fuzzy Metric Approach to Aggregation of Risk Levels

2019

In this paper we propose a special construction of a general aggregation operator. The construction allows to aggregate fuzzy sets taking into account the distance between elements of the universe. We consider the case when fuzzy sets to be aggregated represent the risk level evaluation by several experts. We describe how the proposed construction could be applied for risk level assessment in the case when a strong fuzzy metric is used to characterize the similarity of objects under evaluation.

FOLATE RECEPTOR-TARGETED SUPRAMOLECULAR VESICULAR AGGREGATES (SVAS)FOR ANTICANCER THERAPY

2009

Hieracium racemosum subsp. lucanum (Asteraceae), a new hawkweed from southern Italy

2019

A new endemic taxon of Hieracium belonging to the H. racemosum aggregate is described from Basilicata (southern Italy) and named H. racemosum subsp. lucanum. Information on its morphology, distribution, ecology and taxonomic relationship is provided.

Electrospray Ion Mobility Mass Spectrometry of positively and negatively charged (1R,2S)-Dodecyl(2-hydroxy-1-methyl-2-phenyl-ethyl)dimethylammonium b…

2016

RATIONALE: Self-assembling processes of surfactants in the gas phase constitute a developing research field of interest since they allow information to be gained on the peculiar structural organization of these aggregates, on their ability to incorporate from small molecules up to proteins and on their possible use as carriers of drugs in the gas phase or as cleaning agents and exotic reaction media. METHODS: The mass spectra of charged aggregates of the chiral surfactant (1R,2S)-dodecyl(2-hydroxy-1-methyl-2- phenylethyl)dimethylammonium bromide (DMEB) in the gas phase have been recorded using a Synapt G2-Si mass spectrometer in the positive and negative ion mode. For comparison purposes, t…

Mechanical and environmental performance comparisons of improved asphalt pavement wearing courses with high quality aggregates, steel slags, and poly…

2023

The use of waste materials in the construction of hot mix asphalt (HMA) pavements is an important opportunity for environmental sustainability. When properly designed, the alternative mixtures may also guarantee excellent mechanical performance. In this study, the results of an experimental analysis carried out on dense-graded HMAs are presented. In particular, the performance of a "traditional" surface mixture with limestone aggregate (designed with neat bitumen or a polymer-modified bitumen within the typical acceptance requirements for intended use in wearing courses) was compared with two alternative mixtures. The research investigated a surface mixture including coarse basaltic aggrega…

Influence of wall-to-floor connections and pounding on pre- and post-diction simulations of a masonry building aggregate tested on a shaking table

2023

AbstractThis paper presents numerical simulations within the frame of the project SERA—AIMS (Seismic Testing of Adjacent Interacting Masonry Structures). The study includes blind pre-diction and post-diction stages. The former was developed before performing the shaking table tests at the laboratory facilities of LNEC (Lisbon), while the latter was carried out once the test results were known. For both, three-dimensional finite element models were prepared following a macro-modelling approach. The structure consisted of a half-scaled masonry aggregate composed by two units with different floor levels. Material properties used for the pre-diction model were based on preliminary tests previou…

Simulation of blind pre-diction and post-diction shaking table tests on a masonry building aggregate using a continuum modelling approach

2023

AbstractMasonry buildings of historical centres are usually organized within aggregates, whose structural performance against seismic actions is challenging to predict and constitutes still an open issue. The SERA—AIMS (Seismic Testing of Adjacent Interacting Masonry Structures) project was developed to provide additional experimental data by testing a half-scale, two-unit stone masonry aggregate subjected to two horizontal components of dynamic excitation. In this context, this paper investigates the reliability of the modelling approach and the assumptions adopted to generate a three-dimensional continuum finite element model. The work involves two stages, namely a blind pre-diction and a…