Search results for "aivot"
showing 10 items of 101 documents
On the quantitative edge of feature and gestalt -based associative learning : learning-related ERP changes in the hippocampus and the prefontal corte…
2004
Spatial source phase : A new feature for identifying spatial differences based on complex-valued resting-state fMRI data
2019
Spatial source phase, the phase information of spatial maps extracted from functional magnetic resonance imaging (fMRI) data by data‐driven methods such as independent component analysis (ICA), has rarely been studied. While the observed phase has been shown to convey unique brain information, the role of spatial source phase in representing the intrinsic activity of the brain is yet not clear. This study explores the spatial source phase for identifying spatial differences between patients with schizophrenia (SZs) and healthy controls (HCs) using complex‐valued resting‐state fMRI data from 82 individuals. ICA is first applied to preprocess fMRI data, and post‐ICA phase de‐ambiguity and den…
Load-dependent alpha suppression is related to working memory capacity for numbers
2022
Alpha suppression is proposed to reflect a surge in cortical excitability to enhance stimulus processing in working memory. The attenuated state of alpha might reflect the prioritisation of behaviourally relevant information, making it a proxy for working memory functioning. Despite the growing interest in utilising the advancement of brain-based measures to evaluate individuals’ cognitive processes, there was a lack of consistent evidence on the relationship between alpha suppression and working memory performance. To investigate whether interindividual differences in alpha suppression might be related to variability in working memory capacity, we recorded participants’ electroencephalogra…
Säännöllinen liikunta tehokkainta aivoterveyden ylläpidossa
2023
CA3–CA1 long‐term potentiation occurs regardless of respiration and cardiac cycle phases in urethane‐anesthetized rats
2023
Breathing and heartbeat synchronize to each other and to brain function and affect cognition in humans. However, it is not clear how cardiorespiratory rhythms modulate such basic processes as synaptic plasticity thought to underlie learning. Thus, we studied if respiration and cardiac cycle phases at burst stimulation onset affect hippocampal long-term potentiation (LTP) in the CA3–CA1 synapse in urethane-anesthetized adult male Sprague–Dawley rats. In a between-subjects design, we timed burst stimulation of the ventral hippocampal commissure (vHC) to systole or diastole either during expiration or inspiration and recorded responses throughout the hippocampus with a linear probe. As classic…
Protein levels of brain-derived neurotrophic factor in the hippocampus of low/high aerobic capacity rats
2010
Hippocrates and Plato have first documented the connection between a healthy mind and body, during a period which launched analytical thinking and philosophy in Ancient Greece. Modern research has also indicated the contribution of an active lifestyle to enhanced brain performance and decreased incidence of neurodegenerative diseases and mood disorders such as Alzheimer’s disease and depression respectively. This has been hypothesized to emerge through mechanisms which are enhanced by exercise and contribute on brain plas-ticity and health. The Neurotrophins hypothesis implicates several molecules in brain plasticity and healthy aging. Among them, Brain-derived Neurotrophic Factor (BDNF) ha…
Ikääntymisen vaikutus visuaaliseen prosessointiin
2012
Tämän pro gradu -tutkielman tarkoituksena oli selvittää aivojen automaattisen muutoksen havaitsemisjärjestelmän toimintaa visuaalisessa järjestelmässä tapahtumasidonnaisten herätevasteiden (ERP) avulla. Lisäksi tutkielmassa haluttiin selvittää ikääntymisen mahdollisia vaikutuksia tämän järjestelmän toimintaan vertailemalla toisiinsa terveiden nuorten aikuisten (n=19, 22-27 vuotta) ja ikääntyneiden (n=10, 69-95 vuotta) visuaalisia herätevasteita N2- ja P3 -komponenteissa. Visuaalinen herätevaste, jota tutkielmassa tarkasteltiin, oli poikkeavuusnegatiivisuus (mismatch negativity, MMN). Tutkielmassa ERP:t rekisteröitiin elektroenkefalografialla (EEG) ja passiivisen oddball -paradigman avulla. …
Fyysinen aktiivisuus pitää yllä aivojenkin terveyttä ja toimintakykyä läpi elämän
2017
Fyysisesti aktiivisilla ikääntyneillä ihmisillä on pienempi riski sairastua muistisairauksiin, kuten Alzheimerin tautiin, ja liikuntaa on ehdotettu jopa muistisairauksien hoidoksi. Positiivinen yhteys aerobisen kunnon ja aivojen rakenteellisen kunnon välillä näkyy vielä yli 80-vuotiailla. Liikunnan vaikutuksia aivojen terveyteen ja oppimisen edellytyksiin tutkitaan nyt monitieteellisesti ja -menetelmällisesti. nonPeerReviewed