Search results for "aloin"

Dihydroisocoumarins, Naphthalenes, and Further Polyketides from Aloe vera and A. plicatilis: Isolation, Identification and Their 5-LOX/COX-1 Inhibiti…

2021

The present study aims at the isolation and identification of diverse phenolic polyketides from Aloe vera (L.) Burm.f. and Aloe plicatilis (L.) Miller and includes their 5-LOX/COX-1 inhibiting potency. After initial Sephadex-LH20 gel filtration and combined silica gel 60- and RP18-CC, three dihydroisocoumarins (nonaketides), four 5-methyl-8-C-glucosylchromones (heptaketides) from A. vera, and two hexaketide-naphthalenes from A. plicatilis have been isolated by means of HSCCC. The structures of all polyketides were elucidated by ESI-MS and 2D 1H/13C-NMR (HMQC, HMBC) techniques. The analytical/preparative separation of 3R-feralolide, 3′-O-β-d-glucopyranosyl- and the new 6-O-β-d-glucopyranosyl…

Effects of combined hormone replacement therapy or its effective agents on the IGF-1 pathway in skeletal muscle.

2010

Objectives To investigate the effects of combined hormone replacement therapy (HRT) and its effective agents on the IGF-1 signaling pathway. Design and methods To examine the effects of HRT on skeletal muscle in vivo, we utilized pre- and post-intervention samples from a randomized double blinded trial with 50–57-year-old women. The intervention included the year-long use of either HRT preparation (2 mg 17β-estradiol, E2; 1 mg norethisterone acetate, NETA, n = 10) or placebo (CO, n = 9). Microarray technology and quantitative PCR (qPCR) were used to study the expression of insulin-like growth factor I (IGF-1) and its splice variants as well as IGF-1 receptor, Akt1, mTOR, FOXO1, FOXO3, atrog…

Kun toimeen tartutaan : tukin tie lautatavaraksi - metsästä maailmalle : Oy Mikko Kaloisen puutavaraliikkeen historia

2015

Color Signals in the Black Grouse (Tetrao tetrix): Signal Properties and Their Condition Dependency

2007

Recent progress in techniques of quantifying betweenindividual differences of color-based ornaments has revealed undiscovered possibilities for research in sexual selection. We present how the color spectra data can be comprehensively used for studying the importance of sexual ornaments in the black grouse and how these ornaments are related to a male condition. For this, we used both correlative field and experimental data. Field data indicated that older males had more chromatic coloration than yearlings. Blue chroma of males was correlated with male mating success. We experimentally manipulated yearling birds with testosterone implants and found that testosterone-implanted males had impa…

Revisiting neutralization theory and its underlying assumptions to inspire future information security research

2022

Over two decades ago, neutralization theory was introduced to information systems research from the field of criminology and is currently emerging as an influential foundation to both explain and solve the information security policy noncompliance problem. Much of what we know about the theory focuses exclusively on the neutralization techniques identified in the original as well as subsequent criminological writings. What is often left unexamined in IS research is the underlying assumptions about the theory’s core elements; assumptions about the actor, the act, the normative system, and the nature of neutralizing itself. The objective of this commentary is to revisit the origin of neutrali…

Mukautuvat viipalointialgoritmit lisäävässä valmistuksessa

2017

Lisäävä valmistus on kasvattanut nopeasti suosiotaan viime vuosina. Viipalointi on oleellinen osa lisäävää valmistusta, mikä vaikuttaa esimerkiksi valmistettavan esineen pinnan laatuun, valmistusnopeuteen sekä mekaanisiin ominaisuuksiin. Tämän tutkielman tarkoituksena on selvittää, minkälaisia ominaisuuksia viipalointialgoritmilta vaaditaan ja minkälaisia menetelmiä niiden toteuttamiseen on olemassa. Mukautuvaa viipalointialgoritmia käyttämällä voidaan nopeuttaa esineen valmistusaikaa ilman, että pinnan laatu heikentyy. Additive manufacturing has rapidly gained popularity in recent years. Slicing is an important part of additive manufacturin processes. It affects the manufactured part’s sur…