Search results for "alpha-particle"

showing 2 items of 2 documents

The Proton-Boron Reaction Increases the Radiobiological Effectiveness of Clinical Low- and High-Energy Proton Beams: Novel Experimental Evidence and …

2021

Protontherapy is a rapidly expanding radiotherapy modality where accelerated proton beams are used to precisely deliver the dose to the tumor target but is generally considered ineffective against radioresistant tumors. Proton-Boron Capture Therapy (PBCT) is a novel approach aimed at enhancing proton biological effectiveness. PBCT exploits a nuclear fusion reaction between low-energy protons and 11B atoms, i.e. p+11B→ 3α (p-B), which is supposed to produce highly-DNA damaging α-particles exclusively across the tumor-conformed Spread-Out Bragg Peak (SOBP), without harming healthy tissues in the beam entrance channel. To confirm previous work on PBCT, here we report new in-vitro data obtained…

Cancer ResearchProtonmedicine.medical_treatmentSobpBragg peakBSH030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineRadioresistancemedicineIrradiationRC254-282Original Researchprotontherapycancer cell killingChemistryalpha-particleNeoplasms. Tumors. Oncology. Including cancer and carcinogensProton-Boron ReactionRadiation therapyCell killingchromosome aberrationsOncology030220 oncology & carcinogenesisCancer researchproton-boron (B) fusion-enhanced proton therapy (PBFEPT)chromosome aberrationBeam (structure)Frontiers in Oncology
researchProduct

In-beam andα-decay spectroscopy of191Poand evidence for triple shape coexistence at low energy in the daughter nucleus187Pb

2002

Prompt gamma rays have been observed for the first time from the neutron-deficient nucleus Po-191 using the recoil-decay tagging technique at the RITU gas-filled separator. In addition improved alp ...

PhysicsNuclear and High Energy PhysicsAstrophysics::High Energy Astrophysical PhenomenaNuclear TheoryGamma rayAlpha-particle spectroscopymedicine.anatomical_structuremedicineGamma spectroscopyNeutronAlpha decayAtomic physicsNuclear ExperimentSpectroscopyNucleusRadioactive decayPhysical Review C
researchProduct