Search results for "amer"

showing 10 items of 2105 documents

Lower rim arylation of calix[n]arenes with extended perfluorinated domains

2006

Abstract Exhaustive O-arylation of p-tert -butylcalix[ n ]arenes 2 ( n  = 4–8) with an excess of 3-pentadecafluoroheptyl-5-pentafluorophenyl-1,2,4-oxadiazole 3 and K 2 CO 3 in refluxing acetonitrile provides an easy entry to a new family of perfluorinated calix[ n ]arenes 1 . The cyclic tetramer furnishes a mixture of cone , partial cone , and 1,2-alternate conformers, while the larger macrocycles afford single products. The structures of all new compounds are substantiated by NMR techniques and MALDI-TOF mass spectral data. Single-crystal X-ray diffraction studies on the pentamer derivative 1b reveal a distorted cone-in conformation of the calixarene cup.

Calixarenes; organofluorine derivativeChemistryPentamerOrganic ChemistryBiochemistryCrystallographychemistry.chemical_compoundTetramerDrug DiscoveryCalixareneCalixarenesSpectral dataAcetonitrileorganofluorine derivativeConformational isomerismDerivative (chemistry)
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Constraining the Pre-atmospheric Parameters of Large Meteoroids: Košice, a Case Study

2016

Out of a total around 50,000 meteorites currently known to science, the atmospheric passage was recorded instrumentally in only 25 cases with the potential to derive their atmospheric trajectories and pre-impact heliocentric orbits. Similarly, while observations of meteors generate thousands of new entries per month to existing databases, it is extremely rare they lead to meteorite recovery (http://www.meteoriteorbits.info/). These 25 exceptional cases thus deserve a thorough re-examination by different techniques—not only to ensure that we are able to match the model with the observations, but also to enable the best possible interpretation scenario and facilitate the robust extraction of …

Camera networkMeteoriteMeteoroid0103 physical sciences010502 geochemistry & geophysicsGeodesy010303 astronomy & astrophysics01 natural sciencesHeliocentric orbitBallistic coefficient0105 earth and related environmental sciences
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Zwecksetzungen und Zielvorstellungen in den Wirtschafts- und Soziallehren des 18. und 19. Jahrhunderts

1982

The essay examines the natural law economics of the eighteenth century and the evolutionist economics of the nineteenth century by focusing on their methods for achieving a common, nebulously articulated goal: individual fulfillment and the happiness and welfare of mankind in a free, harmoniously ordered society. Illustrating the theoretical and, in practice, effective theories derived from natural law are cammeralism, the economic philosophy of the Physiocrats, and economic liberalism. It is emphasized that these theories do not represent a linear sequence of ideas in which one set of ideas „triumphed” over a preceding one. They show instead three different consequences reflecting the inte…

CameralismDialecticEconomic liberalismHistoryHistory and Philosophy of ScienceNatural lawPhilosophy and economicsSociologyEmpiricismPositivismEpistemologySocial theoryBerichte zur Wissenschaftsgeschichte
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L'inquadramento giuridico delle Aziende speciali

2011

Le Aziende speciali delle Camere di commercio: nuove frontiere di intervento

Camere di Commercio
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Le camere riverberanti presso il laboratorio di acustica dell’Università di Palermo

2010

Camere riverberanti laboratorio di acustica
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Flow cytometry diagnosis in myelodysplastic syndrome: Current practice in Latin America and comparison with other regions of the world

2019

Background: Flow cytometry (FC) is a valuable tool for the diagnosis of myelodysplastic syndromes (MDS). We present results of a survey carried out to evaluate FC current practice for MDS diagnosis in Latin America (LA), focusing on markers used and characteristics of the clinical diagnostic report. Compliance to IMDSflow recommendations was also evaluated. These practices were then compared with those used in other countries. Methods: An online survey was sent through the Grupo Latino-Americano de Mielodisplasia to LA cytometrists and other international scientific societies. Results: 91 responses from 15 LA countries were received. The median of the number of markers used was 20 +/- 4.5, …

CanadaCancer Researchmedicine.medical_specialtyAsiaLatin AmericansOceaniaImmunophenotyping03 medical and health sciencesEuropean LeukemiaNet0302 clinical medicineSurveys and QuestionnairesDiagnosismedicineHumansFlow cytometryPractice Patterns Physicians'SurveyGeographybusiness.industryMyelodysplastic syndromesHematologyFlow Cytometrymedicine.diseaseUnited StatesEuropeClinical PracticeLatin AmericaOncologyCurrent practiceMyelodysplastic Syndromes030220 oncology & carcinogenesisFamily medicineAfricabusinessMyelodysplastic syndromeBackground flowBiomarkers030215 immunologyLeukemia Research
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Cytotoxicity of medicinal plants of the West-Canadian Gwich׳in Native Americans towards sensitive and multidrug-resistant cancer cells

2015

Abstract Ethnopharmacological relevance Traditional medicine of the Native Americans has a long tradition of medicinal plants, which also influenced modern oncology. For instance, podophyllotoxin the active ingredient of Podophyllum peltatum L. (Berberidaceae) used by Native Americans to treat warts led to the development of etoposide and teniposide. In the present investigation, we studied 10 medicinal plants used by the Gwich׳in First Nation of West-Canada, which have been used against diverse diseases including cancer. Material and methods Sensitive and multidrug-resistant (MDR) tumor cell lines expressing various ATP-binding cassette (ABC) transporters (P-glycoprotein/ ABCB1/MDR1 , MRP1…

CanadaCell SurvivalAntineoplastic AgentsDrug resistancePharmacologyBerberidaceaeCell Line TumorDrug DiscoveryLiliaceaemedicineAraceaeHumansMedicinal plantsEtoposidePharmacologyPlants MedicinalbiologyPlant Extractsbiology.organism_classificationDrug Resistance MultipleArctiumMultiple drug resistancePodophyllotoxinDrug Resistance NeoplasmIndians North AmericanATP-Binding Cassette TransportersArctiumPodophyllum peltatummedicine.drugJournal of Ethnopharmacology
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Evidence for cryptic glacial refugia from North American mountain sheep mitochondrial DNA

2006

The separation of populations by ice sheets into large refugia can account for much of the genetic diversity found in present day populations. The evolutionary implications of small glacial refugia have not been as thoroughly explored. To examine refugial origins of North American mountain sheep Ovis spp., we analyzed a 604 bp portion of the mitochondrial DNA (mtDNA) control region from 223 O. dalli and O. canadensis. Major refugia were identified in eastern Beringia and southern North America, and we found evidence for two smaller refugia situated between the Laurentide and Cordilleran glaciers. Our results are the first to demonstrate support for survival of any organism in the latter two…

CanadaMitochondrial DNAClimateAnimals WildEnvironmentBiologyDNA MitochondrialBeringiaMountain sheepEvolution Molecularcvg.developerGenetic variationAnimalsIce CoverGlacial periodcvgEcology Evolution Behavior and SystematicsgeographyGenetic diversitySheepgeography.geographical_feature_categoryModels GeneticEcologyAltitudeGenetic VariationGlacierNorth AmericaIce sheetJournal of Evolutionary Biology
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Biopiracy and the right to self-determination of indigenous peoples.

2018

Abstract Background: Since over thirty years, I work on the unclear legal situation of in which indigenous peoples find themselves today in the beginning mainly in the USA and later also in Canada, Australia and New Zealand. The status of indigenous people and native nations is characterized as a mixture of national and international law. Hypothesis/Purpose: To clarify the status of indigenous people it is necessary to analyze and interpret carefully hundreds of old treaties, international declarations and covenants, national statutes and jurisprudence, especially the old leading decisions of the US-Supreme Court. Such an analysis and interpretation should prove that indigenous people have …

CanadaUnited NationsPharmaceutical ScienceTheftIndigenousStatute03 medical and health sciences0302 clinical medicinePopulation GroupsPolitical scienceDrug DiscoveryComparative lawHumansTreaty030304 developmental biologyPharmacology0303 health sciencesAustraliaDeclaration on the Rights of Indigenous PeoplesBiodiversityInternational lawIndigenous rightsUnited StatesComplementary and alternative medicine030220 oncology & carcinogenesisLawPersonal AutonomyIndians North AmericanMolecular MedicineMinority rightsNew ZealandPhytomedicine : international journal of phytotherapy and phytopharmacology
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Dolarización panamericana

2001

CanadáAntiglobalizaciónCumbre de los PueblosPolíticas socialesVidal-Beneyto JoséEducaciónTLCÁrea de Libre Comercio de las AméricasLibertadesPueblosEconomía sostenibleEconomíaPublicaciones: Obra periodística: Columnas y artículos de opiniónCumbre de las AméricasGlobalizaciónMinorías étnicasIntegración latinoamericanaSeattleALCAPanamericanismoMéxicoMujeresAlternativasMercado Común PanamericanoUltraliberalismoProtecciónMedio ambienteDerechosContinente americanoEEUUTratado de Libre Comercio
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