Search results for "amine"
showing 10 items of 7299 documents
University Students´ Knowledge Construction during Face to Face Collaborative Writing
2014
Collaborative writing combines social processes of writing with cognitive knowledge construction processes, and thus may lead to deeper learning than individual working. This study examined students’ knowledge construction during face-to-face collaborative writing. University students (n = 21) prepared themselves for the collaborative task by reading about developmental theories in a course book and writing individual summaries of them. In small groups, the students discussed each others’ summaries and wrote a joint essay on one of the theories. The data comprise the students’ individual summaries (n = 21), the students’ discussions during the essay writing (8177 speech turns), and the stud…
Therapeutic metaphors and personal meanings in group poetry therapy for people with schizophrenia
2021
This article concerns the therapeutic potential of metaphor in group poetry therapy, concentrating on the poetry therapy process of people diagnosed with schizophrenia. The data was collected in a one-year poetry therapy group. The main questions were: (1) What kind of therapeutic potential can metaphors offer in group poetry therapy? (2) What are the personal meanings and evaluations that the participants give to the therapy process and its effects on their lives? (3) What are the most significant elements in poetry therapy from the viewpoint of the client? The analysis was based on the Grounded theory method. The results showed that the most significant therapeutic factors of the process …
New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy
2020
[EN] Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug concentration in injured tissues and less systemic adverse effects, as consequence of less/null drug absorption in small intestine. This review focused on the reported contributions in the last four years to improve the effectiveness of treatments of inflammatory bowel diseases. The work concludes that there has been an increase in the development of CDDS in which pH, specific enzymes, reactive oxygen species (ROS), or a combination of all of these triggers the release. These delivery systems demonstrated a th…
Exposure to Gastric Acid Inhibitors Increases the Risk of Infection in Preterm Very Low Birth Weight Infants but Concomitant Administration of Lactof…
2018
Objective: To investigate whether exposure to inhibitors of gastric acidity, such as H2 blockers or proton pump inhibitors, can independently increase the risk of infections in very low birth weight (VLBW) preterm infants in the neonatal intensive care unit. Study design: This is a secondary analysis of prospectively collected data from a multicenter, randomized controlled trial of bovine lactoferrin (BLF) supplementation (with or without the probiotic Lactobacillus rhamnosus GG) vs placebo in prevention of late-onset sepsis (LOS) and necrotizing enterocolitis (NEC) in preterm infants. Inhibitors of gastric acidity were used at the recommended dosages/schedules based on the clinical judgmen…
Dye-Labeled Poly(organosiloxane) Microgels with Core−Shell Architecture
1999
Poly(organosiloxane) microgels are highly cross-linked rather monodisperse spherical particles of radius about 10 nm. Using a functionalized silane comonomer, i.e., (chlorobenzyl)trimethoxysilane, model particles suitable for studies in colloid physics are available: photoreactive and fluorescent dyes can be covalently bound within the microgels to prepare tracers for diffusion studies using forced Rayleigh scattering (FRS) and fluorescence correlation spectroscopy (FCS). For the application as tracer particles, it is important not to influence the diffusion behavior by the coupled chromophores. Therefore, functionalized precursors with a core−shell architecture are used to minimize labeli…
A tale of two frames : Exploring the role of framing in the use discontinuance of volitionally adopted technology
2022
https://doi.org/10.1111/isj.12355 The discontinuance of volitional IS (i.e., information systems adopted, used and discontinued at will) has recently attracted remarkable attention from academics and practitioners alike. However, most research to date has been ahistorical. Ignoring the temporal progression can be problematic when the phenomenon under investigation is dynamic and evolving. To balance this, we adopt a stage modelling approach to understand the process ending with the technology use being discontinued by users of a popular crowdsourcing platform. Two questions guided our investigation: (1) Why do users discontinue using an IS they have volitionally adopted and used? (2) How do…
Combining conjunctive rule extraction with diffusion maps for network intrusion detection
2013
Network security and intrusion detection are important in the modern world where communication happens via information networks. Traditional signature-based intrusion detection methods cannot find previously unknown attacks. On the other hand, algorithms used for anomaly detection often have black box qualities that are difficult to understand for people who are not algorithm experts. Rule extraction methods create interpretable rule sets that act as classifiers. They have mostly been combined with already labeled data sets. This paper aims to combine unsupervised anomaly detection with rule extraction techniques to create an online anomaly detection framework. Unsupervised anomaly detectio…
Register data in sample allocations for small-area estimation
2018
The inadequate control of sample sizes in surveys using stratified sampling and area estimation may occur when the overall sample size is small or auxiliary information is insufficiently used. Very small sample sizes are possible for some areas. The proposed allocation based on multi-objective optimization uses a small-area model and estimation method and semi-collected empirical data annually collected empirical data. The assessment of its performance at the area and at the population levels is based on design-based sample simulations. Five previously developed allocations serve as references. The model-based estimator is more accurate than the design-based Horvitz–Thompson estimator and t…
Building a Maturity Model for Developing Ethically Aligned AI Systems
2021
Ethical concerns related to Artificial Intelligence (AI) equipped systems are prompting demands for ethical AI from all directions. As a response, in recent years public bodies, governments, and companies have rushed to provide guidelines and principles for how AI-based systems are designed and used ethically. We have learned, however, that high-level principles and ethical guidelines cannot be easily converted into actionable advice for industrial organizations that develop AI-based information systems. Maturity models are commonly used in software and systems development companies as a roadmap for improving the performance. We argue that they could also be applied in the context of develo…
Too many passwords? : How understanding our memory can increase password memorability
2018
Passwords are the most common authentication mechanism, that are only increasing with time. Previous research suggests that users cannot remember multiple passwords. Therefore, users adopt insecure password practices, such as password reuse in response to their perceived memory limitations. The critical question not currently examined is whether users’ memory capabilities for password recall are actually related to having a poor memory. This issue is imperative: if insecure password practices result from having a poor memory, then future password research and practice should focus on increasing the memorability of passwords. If, on the other hand, the problem is not solely related to memory…