Search results for "amine"
showing 10 items of 7299 documents
Kirjoittamisen opettamisen disiplinaarisista kamppailuista
2019
Kirjoittamisen rooli koulutuksen kaikilla tasoilla perusopetuksesta korkeakouluun on monimutkainen, hieman provosoivasti sen voi sanoa jopa perversoituneen. Kirjoittaminen on yhä vahvemmin mittaamisen, arvioinnin ja hallinnan väline. Kirjoittamisen roolilla opettajankoulutuksessa on suoria vaikutuksia siihen, miten tulevat opettajat toimivat koulussa. Keskityn artikkelissa kirjoittamisen opettamisen ja opiskelun disiplinaaririsiin kamppailuihin. Disipliini – kuri, järjestys, oppiaine – kuuluu kasvatuksen ydinkäsitteisiin niin käytännössä kuin teoriassakin. Tapausesimerkkinä käytän Jyväskylän yliopistossa vuosituhannen alusta toteutettua koulutus- ja tutkimusmallia, integraatiokoulutusta, jo…
The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle
1992
Cromakalim (BRL 34915) is a potassium channel opener with therapeutic potential as a bronchodilator in asthma. Cromakalim (0.1–30 μmol/l) inhibited the spontaneous tone of human isolated bronchi n a concentration-related manner being nearly as effective as isoprenaline or theophylline. The order of relaxant potencies (expressed as -log10 IC50 mol/l; mean ±SEM) was isoprenaline (7.29 ± 0.27; n = 8) > cromakalim (5.89 ± 0.12; n = 7) > theophylline (4.07 ±0.13; n = 10). In human bronchi where tone had been raised by addition of histamine (0.1 mmol/l), acetylcholine (0.1 mmol/l) or leukotriene D4 (LTD4, 0.1 μmol/l), the relaxant effect of cromakalim was substantially reduced. Cromakalim suppres…
Using Blockchain in Digitalizing Enterprise Legacy Systems: An Experience Report
2021
Blockchain technology and distributed ledger technology (DLT) offer a secure, distributed, and tamper-proof way to store and exchange information. However, apart from standard cryptocurrency-based networks, innovations and process improvements based on the blockchain technology have mostly remained on the conceptualizing stage and have not yet reached mass adoption. There is a high demand for practical experiences from developing blockchain and DLT based systems in various domains outside FinTech. This work seeks to contribute to this gap by presenting real-world experiences from developing a proof of concept for automatizing conditional payments in social benefits and healthcare domains. W…
Decacyclene as complexation manifold: synthesis, structure and properties of its Fe2 and Fe4 slipped triple-decker complexes.
2006
Reaction of [(eta(5)-Me4EtC5)Fe(II)Cl(tmeda)] (tmeda = N,N,N'N'-tetramethylethylenediamine) with a polyanion solution of decacyclene (1) results in the formation of the triple-deckers [{(eta(5)-Me4EtC5)Fe}2-mu2-(eta(6):eta(6)-decacyclene)] (3) and [{(eta(5)-Me4EtC5)Fe}4-mu4-(eta(6):eta(6):eta(6):eta(6)-decacyclene)] (4). Metal complexation in 3 and 4 occurs on opposite faces of the pi perimeter in an alternating mode. The decacyclene ring adopts a gently twisted molecular propeller geometry with twofold crystallographic symmetry (C2). Complex 4 crystallizes in the chiral space group C222(1); the investigated crystal only contains decacyclene rings with M chirality. The handedness can be ass…
4-[3-(4-Fluorophenyl)quinoxalin-2-yl]-N-isopropylpyridin-2-amine
2009
In the crystal structure of the title compound, C22H19FN4, the quinoxaline system makes dihedral angles of 32.07 (13) and 69.64 (13)° with the 4-fluorophenyl and pyridine rings, respectively. The 4-fluorophenyl ring makes a dihedral angle of 71.77 (16)° with the pyridine ring. The crystal structure is stabilized by intermolecular N—H...N hydrogen bonding.
Humidity-Driven Reversible Transformation and Guest Inclusion in a Two-Dimensional Coordination Framework Tailored by Organic Polyamine Cation
2011
Using a polyamine cation tetrenH55+ (tetren = tetraethylenepentaamine), we tailored the dynamic layered material (tetrenH5)1.6{CoII(H2O)2[MIV(CN)8]}4·xH2O (1, M = W, x = 12; 2, M = Mo, x = 11.2). 1 and 2 consist of strongly corrugated two-dimensional (2D) cyano-bridged monolayers {CoII(H2O)2[MIV(CN)8]}n2n– of square grid topology stacked in an alternate manner with cationic layers of tetrenH55+ and H2O molecules. The observed single-crystal-to-single-crystal (SCSC) transformation is due to the reversible dehydration of 1 and 2 to the respective monocrystalline materials (tetrenH5)1.6{CoII[MIV(CN)8]}4 (1deh and 2deh). Structural modifications consist of the change of coordination number (C.N…
Dog blogs as ventriloquism: Authentication of the human voice
2015
This paper looks at personal blogging by dog owners in an international, English language blogsite in which dog owners from around the world report and reflect upon their dogs and their lives with dogs, and do so by using the dog׳s voice. It approaches dog blogs as an example of the strategic use of pervasive but contentious anthropomorphic western discourses about animals and discusses how dog bloggers use anthropomorphism as a discursive means for crafting and collectively ratifying authenticity in a translocal, interest-driven and informal social media context in which traditional territorial and demographic parameters of authenticity are not easily available or relevant. More specifical…
Workers’ and volunteers’ ideas about the benefits of young people’s cultural participation : a critical capital-based approach
2020
This article deals with non-profit sector and voluntary workers’ understandings of the benefits of young people’s participation in cultural and leisure projects in Central Finland. Active participation is highlighted on a policy level as a solution to social inequality, exclusion, and marginalisation among young people. The article focuses on the cultural, social, economic, and political dimensions of participation by exploring the advantages that cultural projects bring to young people. The article theorises these dimensions by drawing on Bourdieu’s concept of capital to provide a more critical account of the participation paradigm. Fifteen workers and volunteers on cultural projects were …
Reframing belonging : affective localism and the early fiction of Reino Rinne
2017
ABSTRACTThe early fiction of a novelist and journalist born in the north of Finland, Reino Rinne (1913–2002), is illustrative of the post-war interest in a redefinition of cultural belonging. The aim of this article is to offer a reading of Rinne’s works that throws light on the way they exemplify a post-war articulation of affective localism. What is especially characteristic of the affective localism produced in Rinne’s early fiction is the deployment of certain narrative elements, realism as an aesthetic regime, tropes of spatial belonging and historical myths that are endowed with affective charge. A comparison between Rinne's first novel Tunturit hymyilevat. Kuvaus Lapista 1900-luvun a…
On the Borderlands of Queer Representations : From Downtown to Neon City, Lapland, and St Petersburg, Russia
2022
Tämä kaksikielinen ”Borderlands of Representation / Representaatioiden rajaseuduilla” -teemanumero käsittelee tunnistamisen ja tunnustamisen rajoja sekä representaatioiden ja tulkinnan politiikkaa sukupuolen, seksuaalisuuden ja ueer-tutkimuksen konteksteissa. Millaiset erot ovat näkyviä, kerrottavia tai luettavissa ja siten avoimia tulkinnoille tai väärintulkinnoille (olivatpa ne tarkoituksellisia tai tahattomia)? Miksi niistä tulee merkityksenantoprosessien ja representaatioiden politiikkaa koskevien kiistojen paikkoja ja jopa poliittisten valtataistelujen areenoita? Miten representaatioiden näkyvyys ja merkitys muuttuvat suhteessa aikaan ja paikkaan, tulkitsijan tarpeisiin ja toiveisiin s…