Search results for "amine"

showing 10 items of 7299 documents

Live free or die motionless : Walking the migrant path from Italy to France

2018

This essay and the photographs examine visual traces of irregular mobility in the border landscape between Italy and France. The ruined buildings and objects witness decades of movement of undocumented people on this old migrant path across the mountains. By taking the theoretical concept of multidirectional memory (Rothberg 2009) the essay argues that the Path of Hope can be thought of as a memory site through which the issues of migration in contemporary Europe can be seen in a more sustainable light. The ruins and discarded objects link memories of different places – including different border zones – in ways that allow us to critically examine borders as a practice – rather than as exis…

Cultural Studiesta520HistoryPath (computing)media_common.quotation_subjectRefugeemigrantsfilmmigrationpaperittomat henkilötmaisemaVisual artsmemoryReading (process)maahanmuuttoborderta616muistaminenlcsh:B1-5802media_commonrouteslcsh:NX1-820lcsh:Philosophy (General)undocumented personslcsh:Arts in generallandscaperefugeesWitnessmaahanmuuttajatItaliaEuropeborder districtsreititItalyrajaseudutraja-alueetFranceBorder zoneRanskapakolaiset
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Leadership in Finnish comprehensive school core curricula since the 1970s

2014

Tiivistelmä – Abstract Suomen peruskoulujärjestelmä sai alkunsa vuonna 1970 ja samana vuonna julkaistiin ensimmäinen peruskoulun opetussuunnitelma. Seuraavat opetussuunnitelmauudistukset toteutettiin vuosina 1985, 1994 ja 2004. Parhaillaan Suomessa kehitetään uutta peruskoulun opetussuunnitelmaa, joka on tarkoitus ottaa käyttöön vuonna 2016. Tässä tutkimuksessa tarkasteltiin johtajuuden ja opetussuunnitelman välistä suhdetta. Tutkimus toteutettiin laadullisena sisällönanalyysina, jossa aineiston muodostivat viralliset opetussuunnitelmat ja kaksi asiantuntijahaastattelua. Tutkimustulokset analysoitiin summatiivisen sisällönanalyysin menetelmin ja tulokset kuvattiin tulkinnallisella menetelmä…

Curriculum theorycomprehensive schoolinstructional leadership1970-lukueducational reformleadership theorypedagogical leadershipperuskoulupedagoginen johtaminenmanagerialismijohtajuusmanagerialismopetussuunnitelmatkoulunuudistus
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Drivers and outcomes of consumer engagement : Insights from mobile money usage in Ghana

2019

Purpose The purpose of this paper is to examine the drivers of consumer engagement and its consequences via the experiences of mobile money services’ users in Ghana and to discuss its implications for the society, financial service innovation, delivery and operations. Design/methodology/approach A pre-tested survey instrument was used with a sample of 595 mobile money services users in Ghana. SmartPLS application was used to analyze the data and report findings. Findings The study shows that perceived risk, consumer empowerment, subjective norm, performance expectancy and effort expectancy influence the affect component of consumer engagement and explain around half of its variance. The ef…

Customer engagementmobiilimaksaminenmaksutconsumer behaviorGhanaFinTechmobiilipalvelut0502 economics and businessMobile paymentmobiilisovelluksetcontinuous usageMarketingConsumer behaviourFinancial servicesconsumer engagementMarketingService (business)Expectancy theorybusiness.industry05 social sciencesService providerkuluttajakäyttäytyminenraha050211 marketingmobile moneybusiness050203 business & management
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Extending customer relationship management. From empowering firms to empowering customers

2013

Purpose – The focus of customer relationship management (CRM) literature has been predominantly on the firm perspective and on IT, not on customer or service orientation and value co-creation. This paper seeks to explore and analyse contemporary CRM frameworks and suggests future research directions. To achieve this, a thorough literature review on CRM is conducted focusing on recent advances within CRM. This provides a good basis for critically analysing the current status of both CRM theory and practice. Design/methodology/approach – The paper reviews CRM literature published 2003-2011. Based on the literature review, it introduces a conceptual framework of the changing role of customer d…

Customer retentionKnowledge managementGeneral Computer ScienceService-orientationComputerApplications_COMPUTERSINOTHERSYSTEMSCustomer relationship managementCustomer advocacyAsiakkuuksien johtaminenasiakaskeskeisyysCustomer to customerCustomer intelligenceta512Service-dominant logicService-dominant logicbusiness.industryInformationSystems_INFORMATIONSYSTEMSAPPLICATIONSasiakkuudenhallintauusi mediaConceptual frameworkasiakastietopalvelukeskeinen logiikkaCustomer dataCustomer centricityuusmediabusinessInformation Systems
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Synthesis, crystal structure and magnetic properties of a new cyanide-bridged mixed-valence copper(I)/copper(II) clathrate

2013

A unique cyanide-bridge mixed-valence CuI/CuII clathrate of formula [CuI2(CN)3][{CuII(tren)}2(μ-CN)](CF3SO3)2 [tren = tris(2-aminoethyl)amine] containing cyanide-bridged [{CuII(tren)}2(μ-CN)]3 + binuclear cations stacked between anionic honeycomb layered copper(I) cyanide networks, was synthesized and structurally characterized by single crystal X-ray diffraction. Variable-temperature magnetic susceptibility studies showed that the cyanide bridge mediates a strong antiferromagnetic interaction between the copper(II) centers (J = − 160 cm− 1, the spin Hamiltonian being defined as H = − JSA⋅SB).

Cyanide bridgeMixed-valence copper(III) complexesValence (chemistry)Binuclear complexCyanideInorganic chemistrychemistry.chemical_elementCrystal structureMagnetic susceptibilityCopperInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryCrystal structuresMagnetic propertiesMaterials ChemistryAntiferromagnetismAmine gas treatingPhysical and Theoretical ChemistrySingle crystalInorganic Chemistry Communications
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Synthesis, characterization and crystal structure of the bimetallic cyano-bridged [(η5-C5H5)(PPh3)2Ru(μ-CN)Ru(PPh3)2(η5-C5H5)][PF6]

2005

Abstract The bimetallic cyano-bridged [(η 5 -C 5 H 5 )(PPh 3 ) 2 Ru(μ-CN)Ru(PPh 3 ) 2 (η 5 -C 5 H 5 )][PF 6 ] ( 1 ) was prepared by reaction of [(η 5 -C 5 H 5 )(PPh 3 ) 2 RuCl] with N , N ′-bis(cyanomethyl)ethylenediamine. The single crystal structure determined by X-ray diffraction showed crystallization on the triclinic P1 space group with a perfect alignment of the cyanide bridges. This accentric crystallization was explored having in view the NLO properties at the macroscopic level, determined by the Kurtz Powder technique. Besides the very low efficiency values for the second harmonic generation, the value obtained for the bimetallic complex 1 showed to be higher than one of the parent…

Cyanidechemistry.chemical_elementEthylenediamineCrystal structureTriclinic crystal systemlaw.inventionRutheniumInorganic Chemistrychemistry.chemical_compoundCrystallographychemistrylawMaterials ChemistryPhysical and Theoretical ChemistryCrystallizationBimetallic stripSingle crystalInorganica Chimica Acta
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Iron(II) metallomesogens based on symmetrical tripod ligands

2012

Abstract Novel mononuclear tripodand-based iron(II) complexes showing liquid crystal properties have been synthesized and characterized. These are based on ligands tris[3-aza-4-((5-Cn)(6-R-2-pyridyl))but-3-enyl]amine, where R = hydrogen or methyl, 1,3,5-cis,cis-tris[1-aza-2-((5-alkyloxy)(2-pyridyl))vinyl]cyclohexane and 2,2,2-tris(2-aza-3-((5-alkyloxy)(2-pyridyl))prop-2-enyl)ethane. The physical characterization has been carried out by means of single-crystal X-ray diffraction measurements, magnetic susceptibility, differential scanning calorimetry, X-ray powder diffraction and Mossbauer spectroscopy.

CyclohexaneChemistryInorganic chemistryTripod (photography)Magnetic susceptibilityInorganic ChemistryCrystallographychemistry.chemical_compoundDifferential scanning calorimetrySpin crossoverMössbauer spectroscopyMaterials ChemistryAmine gas treatingPhysical and Theoretical ChemistryPowder diffractionInorganica Chimica Acta
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Ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir, plus ribavirin for patients with hepatitis C virus genotype 1 or 4 infection with…

2017

Summary Background We ran a compassionate use nationwide programme (ABACUS) to provide access to ombitasvir, paritaprevir, and ritonavir, with dasabuvir, plus ribavirin for hepatitis C virus (HCV) genotype 1 infection and ombitasvir, paritaprevir, and ritonavir, plus ribavirin for HCV genotype 4 infection in patients with cirrhosis at high risk of decompensation while approval of these regimens was pending in Italy. Methods In this prospective observational study, we collected data from a compassionate use nationwide programme from March 17, 2014, to May 28, 2015. Patients with HCV genotype 1 infection and cirrhosis at high risk of decompensation were given coformulated ombitasvir (25 mg), …

CyclopropanesCompassionate Use TrialsLiver CirrhosisMalechemistry.chemical_compound0302 clinical medicine2-NaphthylamineHCV direct-acting antiviral mixed cryoglobulinemia RBVAnilides030212 general & internal medicineLongitudinal StudiesProspective StudiesChronicAdult; Aged; Anilides; Antiviral Agents; Carbamates; Compassionate Use Trials; Drug Therapy Combination; Female; Genotype; Hepatitis C Chronic; Humans; Liver Cirrhosis; Longitudinal Studies; Macrocyclic Compounds; Male; Middle Aged; Prospective Studies; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; UracilSettore MED/12 - GastroenterologiaSulfonamidesDasabuvirHCV DAAGastroenterologyvirus diseasesValineMiddle AgedSettore MED/07 - Microbiologia e Microbiologia ClinicaHepatitis CTreatment OutcomeGastroenterology; HepatologyCombinationDrug Therapy Combination030211 gastroenterology & hepatologyFemalemedicine.drugAdultmedicine.medical_specialtyMacrocyclic CompoundsProlineGenotypeLactams MacrocyclicAdult; Aged; Anilides; Antiviral Agents; Carbamates; Compassionate Use Trials; Drug Therapy Combination; Female; Genotype; Hepatitis C Chronic; Humans; Liver Cirrhosis; Longitudinal Studies; Macrocyclic Compounds; Male; Middle Aged; Prospective Studies; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; Uracil; Hepatology; GastroenterologyHepatitis C virus genotype 1 Hepatitis C virus genotype 4 decompensated liver cirrhosis antiviral therapy dasabuvir ombitasvir paritaprevirHepatology; GastroenterologyAntiviral Agents03 medical and health sciencesDrug TherapyInternal medicineRibavirinmedicineHumansDecompensationAdverse effectUracilAgedRitonavirHepatologybusiness.industryRibavirinHepatitis C ChronicVirologyOmbitasvirClinical trialchemistryParitaprevirRitonavirCarbamatesbusiness
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Safety and efficacy of ombitasvir/paritaprevir/ritonavir/dasabuvir plus ribavirin in patients over 65 years with HCV genotype 1 cirrhosis

2018

Purpose: To analyse safety and efficacy of treatment based on ombitasvir/paritaprevir/ritonavir/dasabuvir plus ribavirin in the sub-group of GT1 patients older than 65 years. Methods: We collected data extracted from the ABACUS compassionate-use nationwide Italian programme, in patients with cirrhosis due to hepatitis C virus (HCV) Genotype-1 (GT1) or 4 and at high risk of decompensation. GT1-HCV-infected patients received once-daily ombitasvir/paritaprevir, with the pharmacokinetic enhancer ritonavir (25/150/100 mg) and twice-daily dasabuvir (250 mg) plus Ribavirin (RBV) (OBV/PTV/r + DSV + RBV) for 12 (GT1b) or 24 (GT1a) weeks. Endpoints were to evaluate safety and efficacy, the latter def…

CyclopropanesLiver CirrhosisMaleCirrhosis;Dasabuvir;Elderly;Ombitasvir;ParitaprevirCirrhosis; Dasabuvir; Elderly; Ombitasvir; Paritaprevir; Aged; Aged; 80 and over; Anilides; Antiviral Agents; Biomarkers; Carbamates; Female; Hepacivirus; Hepatitis C; Chronic; Humans; Liver Cirrhosis; Macrocyclic Compounds; Male; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; Uracil; Drug Therapy; Combination; GenotypeParitaprevirCirrhosis Dasabuvir Elderly Ombitasvir Paritaprevir Microbiology (medical) Infectious DiseasesCirrhosis; Dasabuvir; Elderly; Ombitasvir; Paritaprevir; Aged; Aged 80 and over; Anilides; Antiviral Agents; Biomarkers; Carbamates; Female; Hepacivirus; Hepatitis C Chronic; Humans; Liver Cirrhosis; Macrocyclic Compounds; Male; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; Uracil; Drug Therapy Combination; Genotype; Microbiology (medical); Infectious DiseasesHepacivirusGastroenterologychemistry.chemical_compound0302 clinical medicineElderly2-Naphthylamine80 and overMedicineAnilides030212 general & internal medicineChronicAged 80 and overSulfonamidesDasabuvirValineGeneral MedicineHepatitis CHepatitis CTreatment OutcomeInfectious DiseasesCirrhosisCombination030211 gastroenterology & hepatologyDrug Therapy CombinationFemaleDasabuvirMacrocyclic CompoundCirrhosis; Dasabuvir; Elderly; Ombitasvir; Paritaprevir; Microbiology (medical); Infectious Diseasesmedicine.drugHumanMicrobiology (medical)medicine.medical_specialtyMacrocyclic CompoundsProlineGenotypeLactams MacrocyclicSettore MED/12 - GASTROENTEROLOGIALiver CirrhosiSulfonamideAntiviral Agents03 medical and health sciencesDrug TherapyInternal medicineRibavirinHumansDecompensationUracilAgedHepatitisAntiviral AgentCirrhosiHepaciviruRitonavirbusiness.industryRibavirinSettore MED/09 - MEDICINA INTERNAAnilideBiomarkerHepatitis C Chronicmedicine.diseaseCirrhosis; Dasabuvir; Elderly; Ombitasvir; Paritaprevir; Aged; Aged 80 and over; Anilides; Antiviral Agents; Biomarkers; Carbamates; Female; Hepacivirus; Hepatitis C Chronic; Humans; Liver Cirrhosis; Macrocyclic Compounds; Male; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; Uracil; Drug Therapy Combination; GenotypeOmbitasvirOmbitasvirchemistryParitaprevirCarbamateRitonavirCarbamatesbusinessBiomarkers
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Real-world experience with the all-oral, interferon-free regimen of ombitasvir/paritaprevir/ritonavir and dasabuvir for the treatment of chronic hepa…

2017

Summary Real-world studies are relevant to complement clinical trials on novel antiviral therapies against chronic hepatitis C; however, clinical practice data are currently limited. This study investigated effectiveness and safety of ombitasvir/paritaprevir/ritonavir (OBV/PTV/r)±dasabuvir (DSV)±ribavirin (RBV) for treatment of HCV genotype (GT) 1 and GT4 infection in a large real-world cohort. The German Hepatitis C Registry is an observational cohort study prospectively collecting clinical practice data on direct-acting antiviral therapies. Patients with GT1/4 infection treated with OBV/PTV/r±DSV±RBV were analysed. Effectiveness was assessed by sustained virologic response in 558 patients…

CyclopropanesLiver CirrhosisMaleHepacivirusSeverity of Illness IndexCohort Studieschemistry.chemical_compound0302 clinical medicine2-NaphthylamineGermanyMedicineAnilides030212 general & internal medicineSulfonamidesDasabuvirValineHepatitis CMiddle AgedViral LoadInfectious DiseasesTreatment Outcome030211 gastroenterology & hepatologyDrug Therapy CombinationFemalemedicine.drugAdultmedicine.medical_specialtyMacrocyclic CompoundsGenotypeProlineLactams Macrocyclic03 medical and health sciencesVirologyOmbitasvir/paritaprevir/ritonavirInternal medicineHumansUracilAgedRitonavirHepatologybusiness.industryHepatitis C Chronicmedicine.diseaseVirologyOmbitasvirDiscontinuationRegimenchemistryParitaprevirRitonavirCarbamatesbusinessJournal of viral hepatitis
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