Search results for "amine"
showing 10 items of 7299 documents
New Hybrid Organic-inorganic Multifunctional Materials Based on Polydopamine-like Chemistry
2021
Taking inspiration from the chemistry of dopamine, a simple and economic synthetic approach toward the synthesis of a series of silica-based polydopamine-like materials has been developed. Mild conditions and easy manipulation are the strongest aspects of this methodology. Such hybrid materials were successfully used as recyclable catalysts for Knoevenagel reactions.
Speechlessness, anxiety, and confusion in a teacher education student group
2017
The aim of the study was to explore the tensions, as experienced by student teachers, in a teacher education program that is based on psychodynamic theory. Previous research shows that students have had orientation problems in innovative university studies because it involves students having to take steps toward their discomfort zone. It was therefore considered important to study the mismatch or match of the training model and student experiences. The data were gathered through student interviews. The data analysis utilized a case study methodology and proceeded from thematic network analysis toward a deeper interpretation of the data. The analysis shows students struggle to understand the…
Über die Beeinflussung der osmotischen Resistenz von Rinder-Erythrocyten
1955
Am Modell der Rindererythrocyten wird die Wirkung von Histamin und Antihistaminica auf die osmotische Resistenz untersucht. Antihistaminica wirken im pH-Bereich von 5–8 bei 0°C und bei 20°C in gleicher Weise hemmend auf die osmotische Resistenz und heben im sauren Bereich (pH 5–6,2) bei 0°C und 20°C die hamolysesteigernde Wirkung des Histamin auf.
Über Histamin als Mittler-Substanz bei der Wirkung von Adrenochrom auf die Blutungszeit
1952
Derouaux1 hat gezeigt, das Adrenalin und Adrenalin-Verwandte in nicht blutdruckwirksamen Dosen imstande sind, die Blutungszeit beim Kaninchen zu verkurzen. Roskam und Mitarbeiter 2, 3 haben ferner eine gleichartige Wirkung auch fur Adrenochrom (ACHR) und das Semicarbazon des Adrenochrom = Adrenoxyl (AX) beschrieben. Kuschinsky, Hille und Emmerich4 haben nachgewiesen, das unter der Einwirkung von ACHR und AX Histamin oder eine ahnlich wirksame Substanz freigemacht wird. Daraufhin entstand die Frage, ob Histamin etwa als Mittlersubstanz bei der Wirkung der obengenannten Stoffe auf die Blutungszeit in Betracht kame. Zur Losung des Problems war es wichtig, festzustellen, ob die Verkurzung der B…
�ber die Wirkung von Adrenochrom und Histamin auf die Blutungszeit
1952
Adrenochrom (ACHR) und das Semicarbazon des Adrenochrom = Adrenoxyl verkurzen die Blutungszeit beim Kaninchen. Die Wirkung last sich durch Antihistaminica aufheben bzw. verhindern. Auch die Wirkung von Histamin, das in analoger Weise wie ACHR die Blutungszeit verkurzt, last sich durch vorherige Gabe eines Antihistaminicum verhindern. Die bereits eingetretene Wirkung von Histamin last sich durch Antihistaminiea nicht mehr aufheben. Die Ergebnisse werden ausfuhrlich im Arch. exper. Path. u. Pharmakol. veroffentlicht.
How bilastine is used to treat allergic rhinitis and urticaria in children
2021
Management guidelines for allergic rhinitis and urticaria recommend oral second-generation antihistamines as first-line treatment. The efficacy and safety of bilastine, the newest nonsedating second-generation antihistamine, are well established in adolescents/adults with these allergic conditions. The bilastine development program for pediatric use (2–<12 years) followed EMA-authorized processes. Pharmacokinetic/pharmacodynamic simulation and modeling and a pharmacokinetic study were conducted to identify and confirm the pediatric dose (10 mg/day). A Phase III, multicenter, double-blind, randomized, placebo-controlled, parallel-group study was performed to confirm the safety of bilasti…
CLONIDINE, A PARTIAL AGONIST OF THE HISTAMINERGIC H2 RECEPTORS?
1978
HSP10,HSP70 AND HSP90 IMMUNOHISTOCHEMICAL LEVELS CHANGE IN ULCERATIVE COLITIS AFTER THERAPY
2011
Ulcerative colitis (UC) is a form of inflammatory bowel disease (IBD) characterized by damage of large bowel mucosa and frequent extra-intestinal autoimmune comorbidities. The role played in IBD pathogenesis by molecular chaperones known to interact with components of the immune system involved in inflammation is unclear. We previously demonstrated that mucosal Hsp60 decreases in UC patients treated with conventional therapies (mesalazine, probiotics), suggesting that this chaperonin could be a reliable biomarker useful for monitoring response to treatment, and that it might play a role in pathogenesis. In the present work we investigated three other heat shock protein/molecular chaperones:…
Laboratory phase‐contrast nanotomography of unstained Bombus terrestris compound eyes
2021
Imaging the visual systems of bumblebees and other pollinating insects may increase understanding of their dependence on specific habitats and how they will be affected by climate change. Current high-resolution imaging methods are either limited to two dimensions (light- and electron microscopy) or have limited access (synchrotron radiation x-ray tomography). For x-ray imaging, heavy metal stains are often used to increase contrast. Here, we present micron-resolution imaging of compound eyes of buff-tailed bumblebees (Bombus terrestris) using a table-top x-ray nanotomography (nano-CT) system. By propagation-based phase-contrast imaging, the use of stains was avoided and the microanatomy co…
The Influence of Cultural Competence on the Interpretations of Territorial Identities in European Capitals of Culture
2014
Abstract The EU’s cultural initiative ‘the European Capital of Culture’ (ECOC) includes high identity political aims. It requires the designated cities to introduce and foster local, regional, and European cultural identities. In addition, the cities have used the designation as an opportunity to promote national cultural identity. Audiences of the ECOC events recognize and interpret different kinds of representations of territorial cultural identities from what the cities have to offer in culture. However, the contents of these interpretations vary drastically in the ECOCs. The article discusses whether the competence of interpreting the representations of territorial cultural identities i…