Search results for "ample"

Functional C1-inhibitor diagnostics in hereditary angioedema: Assay evaluation and recommendations

2008

Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of potentially life-threatening angioedema. The most widespread underlying genetic deficiency is a heterozygous deficiency of the serine protease inhibitor Cl esterase inhibitor (C1-Inh). In addition to low C4 levels, the most important laboratory parameter for correct diagnosis of HAE or angioedema due to acquired C1-Inh deficiency is reduced C1-Inh function (fC1-Inh). No direct recommendations about the assays for fC1-Inh or sample handling conditions are available, although this would prove especially useful when a laboratory first starts to offer assays on fC1-Inh for HAE diagnosis. In the p…

In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats

2019

Graphical abstract

Executive Compensation and Macroeconomic Fluctuations

2008

Macroeconomic fluctuations affect corporations' performance through demand and cost conditions. Incentive effects of performance-based compensation schemes for management may be weakened or biased by macroeconomic influences if management is unable to forecast macroeconomic fluctuations or unable to adjust operations in response to changes in macroeconomic conditions. In this paper we analyze the impact of macroeconomic, industry and firm-specific factors on salaries and bonus of CEOs in 131 Swedish corporations during the period 2001-2006. A distinction is made between anticipated and unanticipated macroeconomic fluctuations. The macroeconomic influences on performance and compensation can…

La violencia de hijos adolescentes contra sus progenitores

2013

[EN] According to Prosecutor¿s Office of the Minor, the accusation interposed by mothers and/or fathers victims by theirs children, along 2007 were 2603, in 2008 amounted 4.211, in 2009 there were 5.209 and in 2010 there were 8.000 accusations. Suede this worrying increase, the principal aim of our article is to check the scientific international and national documentation, from 1957 until the year 2010 that analyses the phenomenon of the adolescent violence against parents, to achieve an approximation to its keys that there allows us the comprehension and analysis of this serious familiar problem. For it we will analyse: (a) the importance of this crime by means of criminological mediators…

The Sustainability Factor: How Much Do Pension Expenditures Improve in Spain?

2020

The reform of 2013 represented a qualitative leap in the reform of the Spanish pension system. Unlike its predecessors, it introduced two automatic resetting mechanisms similar to those of other European countries. The first is the sustainability factor, scheduled to come into effect in 2019 but delayed until 2023, and its ultimate reversal cannot be ruled out. The objective of this study was to quantify the savings, or the lowest expenditure, that can be achieved in the Spanish public contributory pension system by applying it. These savings are measured in terms of cash&mdash

Assessing the efficiency of wastewater treatment plants in an uncertain context: a DEA with tolerances approach

2012

Abstract As the number of wastewater treatment plants (WWTPs) has increased, the economics associated with their management have become more relevant. The efficiency assessment is therefore a useful tool for cost reduction. For this purpose, Data Envelopment Analysis (DEA) is a highly suitable technique, since it is a holistic approach that aggregates performance indicators into a single index. However, one of the most common criticisms of DEA models is that information on uncertainty estimates is not provided. To overcome this limitation, we assess efficiency by using a DEA model with statistical tolerances for both inputs and outputs. This model is applied to a sample of Spanish WWTPs. Th…

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2010

OBJETIVO: Avaliar a validade fatorial e de construto da versão brasileira do "Cuestionario para la Evaluación del Síndrome de Quemarse por el Trabajo" (CESQT). MÉTODOS: O processo de versão do questionário original do espanhol para o português incluiu as etapas de tradução, retrotradução e equivalência semântica. Foi realizada análise fatorial confirmatória e utilizados modelos de equações estruturais de quatro fatores, similar ao da estrutura original do CESQT. A amostra foi constituida de 714 professores que trabalhavam em instituições de ensino da cidade de Porto Alegre, RS, e região metropolitana 2008. O questionário possui 20 itens distribuídos em quatro subescalas: Ilusão pelo trabalh…

Evaluating the Eco-Efficiency of Wastewater Treatment Plants: Comparison of Optimistic and Pessimistic Approaches

2020

The assessment of wastewater treatment plant (WWTP) performance has gained the interest of water utilities and water regulators. Eco-efficiency has been identified as a powerful indicator, as it integrates economic and environmental variables into a single index. Most previous studies have employed traditional data envelopment analysis (DEA) for the evaluation of WWTP eco-efficiency. However, DEA allows the selection of input and output weights for individual WWTPs for the calculation of eco-efficiency scores. To overcome this limitation, we employed the double-frontier and common set of weights methods to evaluate the eco-efficiency of a sample of 30 WWTPs in Spain. The WWTPs were ranked b…

2019

Abstract This paper presents an index that measures reviewer contribution to editorial processes of scholarly journals. Following a metaphor of ranking algorithms in sports tournaments, we created an index that considers reviewers on different context-specific dimensions, i.e., report delivery time, the length of the report and the alignment of recommendations to editorial decisions. To test the index, we used a dataset of peer review in a multi-disciplinary journal, including 544 reviewers on 606 submissions in six years. Although limited by sample size, the test showed that the index identifies outstanding contributors and weak performing reviewers efficiently. Our index is flexible, cont…

Measuring socio-demographic differences in volunteers with a value-based index: illustration in a mega event

2013

The phenomenon of volunteering can be analysed as a consumer experience through the concept of value as a trade-off between benefits and costs. In event volunteering, both the expected value (pre-experienced) and the perceived value (post-experienced) of volunteering can be assessed. With this purpose, an online quantitative survey is conducted with a sample of 711 volunteers in a religious mega event, with questions related to five dimensions of their experience: efficiency, social value, play, spirituality and time spent. These five scales, properly tested are used for building a multidimensional index of both the expected and perceived value of the volunteer experience. ANOVAs test show …