Search results for "anger"

PSA-based phase regeneration of DPSK signals in a silicon germanium waveguide

2015

We demonstrate a polarization-assisted PSA-based phase regenerator in a passive low-birefringence SiGe waveguide at low CW pump power. A PSER of 28.6-dB enables a six-fold reduction in phase-error and BER improvement of approximately 2-dB in the regenerated signal.

UV Exposure Boosts Transcutaneous Immunization and Improves Tumor Immunity: Cytotoxic T-Cell Priming through the Skin

2010

Immunologic approaches to combat cancer aim at the induction of tumor-reactive immune responses to achieve long-term protection. In this context, we recently developed a transcutaneous immunization (TCI) method using the Toll-like receptor (TLR) 7 agonist imiquimod and a peptide epitope. Application onto intact skin induces potent cytotoxic T lymphocyte (CTL) responses and protection against transplanted tumors. The purpose of this study was to explore the effects of UV irradiation on imiquimod-based TCI. Here we show that skin exposure to low-dose UV light before TCI with imiquimod strongly boosts specific CTL responses leading to memory formation and enhanced tumor protection. Toward the …

Multifaceted contributions of epidermal langerhans cells to cutaneous carcinogenesis.

2015

Cutaneous squamous cell carcinoma (SCC) is the most prevalent invasive malignancy with metastatic potential. The epidermis is exposed to a variety of environmental DNA-damaging chemicals, principal among which are polyaromatic hydrocarbons (PAH) ubiquitous in the environment, tobacco smoke, and broiled meats. Langerhans cells (LC) comprise a network of dendritic cells situated adjacent to basal, suprabasal, and follicular infundibular keratinocytes that when mutated can give rise to SCC, and LC-intact mice are markedly more susceptible than LC-deficient mice to chemical carcinogenesis provoked by initiation with the model PAH, 7,12-dimethylbenz[a]anthracene (DMBA). LC rapidly internalize an…

Examination of the Helminth Fauna of the Bermuda Skink, Plestiodon longirostris (Scincidae), Utilizing Faecal Analysis

2021

Plestiodon longirostris is a critically endangered endemic skink living in the Bermuda archipelago. To know their intestinal parasites and evaluate the role that they may have in the conservation of the species, we have carried out a faecal analysis of some samples obtained from several populations. This type of analysis is presented as the most suitable for threatened species. The results show that P. longirostris has incorporated parasites from introduced species in Bermuda, and it is a competent host for these parasites. Nevertheless, the low prevalence of infection of these parasites suggests that they are not actually a threat to the endemic skink populations.

Some Detrimental Effects of Negative Mood on Individuals' Ability to Solve Resource Dilemmas

1991

This research examined the effects of induced mood on subjects' problem-solving behavior In an initial study, an experimenter induced one of three emotions (happiness, sadness, or anger) or no emotion in subjects. Shortly thereafter a second experimenter asked each subject to solve a resource dilemma problem. Subjects in the sad and angry mood conditions were less successful (i.e., they were more likely to deplete limited resources, and they achieved less profit) than subjects in the happy or neutral mood condition. Performance of subjects in positive moods did not differ from that of subjects in neutral moods. In a second study, the effect of a sad mood leading to less success than a neut…

At‐risk children's causal inferences given emotional feedback and their understanding of the excuse‐giving process

1994

Italian male school children, ranging in age from 7 to 10 years, were identified as at‐risk children on the basis of self‐reports, teacher questionnaires, and peer nominations assessing aggression, emotional instability, and pro‐social behaviour. Together with a normal control sample, these children participated in two studies guided by attribtional theory. In Study 1, following teacher emotional feedback of anger or sympathy for failure, attributional inferences regarding low ability or lack of effort as the cause of that failure were rated. In Study 2, controllable and uncontrollable causes of a social transgression were given, and participants rated the anticipated anger of the ‘victim’…

Characteristics of young offenders depending on the type of crime

2015

The aim of this study is to define a profile of juvenile offenders depending on the type of crime (against property or against persons), according to several socio-demographic variables, and a number of indicators of juvenile risk. Participants were 395 adolescents between the ages of 14 and 18 with a criminal record in the juvenile court over a two-year follow-up period. Results showed that in property-related offences the offender is more likely to be male, from an Eastern European country, and with inconsistent parenting. On the other hand, crimes against persons would be committed mostly by girls, Latin American or African juveniles, and with individual factors such as aggressive behavi…

2021

The coach-created motivational climate influences variations in athletes’ motivation and emotional experiences. The present study aimed to examine social environmental antecedents of athletes’ emotions. Participants (N = 262, 52% female, M age = 22.75 ± 6.92) completed questionnaires assessing perceptions of coach-created motivational climates, goal orientations, motivation regulations, and emotions. The mediation effects of goal orientations (i.e., task/ego) and motivation regulations (i.e., autonomous/controlled) on the relationship between motivational climate (i.e., empowering/disempowering) and emotions (i.e., happiness, excitement, anxiety, dejection, and anger) were examined. Structu…

Believing in Hidden Plots is Associated with Decreased Behavioral Trust: Conspiracy Belief as Greater Sensitivity to Social Threat or Insensitivity T…

2022

Abstract Past research has demonstrated that conspiracy belief is linked to a low level of self-reported general trust. In four experimental online studies (total N = 1105) we examined whether this relationship translated into actual behavior. Specifically, since the decision to trust relies on the ability to detect potential social threat, we tested whether conspiracy believers are better at detecting actual threat, worse at detecting the absence of threat, or simply trust less, irrespective of any social cue. To this end, participants played multiple, independent rounds of the trust game, a behavioral measure for interpersonal trust. We manipulated social threat by presenting photographs …

A halocin acting on Na+/H+ exchanger of Haloarchaea as a new type of inhibitor in NHE of mammals

2006

10 páginas, 3 figuras.