Search results for "anger"

showing 10 items of 929 documents

Current Progress in Particle-Based Systems for Transdermal Vaccine Delivery

2020

Transcutaneous immunization (TCI) via needle-free and non-invasive drug delivery systems is a promising approach for overcoming the current limitations of conventional parenteral vaccination methods. The targeted access to professional antigen-presenting cell (APC) populations within the skin, such as Langerhans cells (LCs), various dermal dendritic cells (dDCs), macrophages, and others makes the skin an ideal vaccination site to specifically shape immune responses as required. The stratum corneum (SC) of the skin is the main penetration barrier that needs to be overcome by the vaccine components in a coordinated way to achieve optimal access to dermal APC populations that induce priming of…

lcsh:Immunologic diseases. AllergyOvalbuminMini ReviewT-Lymphocytesparticulate systemsImmunologyAntigen-Presenting CellsAdministration CutaneousSonicationDrug Delivery SystemsImmune systemtranscutaneous immunizationAdjuvants ImmunologicAntigenvaccine particlesStratum corneumHumansImmunology and AllergyMedicineVaccines Virus-Like ParticleParticle SizeTransdermalIontophoresisintegumentary systembusiness.industryElectroporationVaccinationDermisPeptide Fragmentsneedle-free vaccinationVaccinationElectroporationmedicine.anatomical_structureLangerhans CellsLiposomesImmunologyDrug deliverydrug deliveryInjections JetnanoparticlesLymph NodesPharmaceutical Vehiclesbusinesslcsh:RC581-607Frontiers in Immunology
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Pairwise and higher-order measures of brain-heart interactions in children with temporal lobe epilepsy

2022

Abstract Objective. While it is well-known that epilepsy has a clear impact on the activity of both the central nervous system (CNS) and the autonomic nervous system (ANS), its role on the complex interplay between CNS and ANS has not been fully elucidated yet. In this work, pairwise and higher-order predictability measures based on the concepts of Granger Causality (GC) and partial information decomposition (PID) were applied on time series of electroencephalographic (EEG) brain wave amplitude and heart rate variability (HRV) in order to investigate directed brain-heart interactions associated with the occurrence of focal epilepsy. Approach. HRV and the envelopes of δ and α EEG activity re…

linear predictionBiomedical Engineeringheart rate variabilityBrainHeartElectroencephalographyCellular and Molecular NeuroscienceEpilepsy Temporal LobeSeizuresSettore ING-INF/06 - Bioingegneria Elettronica E InformaticaHumansGranger causality (GC)epilepsyEpilepsies PartialChildinformation dynamics
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Écrire pour la jeunesse, stratégie ou achèvement ?

2011

Cette contribution n’apprendra rien au lecteur sur Tournier. D’ailleurs, mes connaissances sur ce dernier proviennent essentiellement, sinon exclusivement, des ouvrages écrits pour beaucoup par d’autres – parmi lesquels nombre de participants à ce colloque. Toutefois j’espère contribuer à mieux le comprendre en éclairant certains de ses choix à la lumière de logiques spécifiques à la littérature pour la jeunesse. Un parcours d’écrivain atypique Précisons pour commencer que contrairement à cer...

littérature jeunesseréception d'une oeuvre[SHS.INFO]Humanities and Social Sciences/Library and information scienceslittérature française à l'étrangerLiterary Theory & Criticism[ SHS.INFO ] Humanities and Social Sciences/Library and information sciencesLIT004150Littérature pour la jeunesseDSBComputingMilieux_MISCELLANEOUS[SHS.INFO] Humanities and Social Sciences/Library and information sciences
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A minireview on NHE1 inhibitors. A rediscovered hope in oncohematology.

2015

Background: Na+/H+ exchanger-1 (NHE-1) is involved in pH regulation and is up-regulated in different malignancies. Activation of NHE-1 is one way for allowing cells to avoid intracellular acidification and protect them against apoptosis. Inhibitors of NHE-1 are able to decrease intracellular pH and induce apoptosis. Some statins can also act by partial inhibition of NHE-1. This review presents progress in understanding the mechanisms of action of these inhibitors, connections with certain genetic mutations and acquired treatment resistance, as well as new patents on them. Methods: A MEDLINE search for original and review articles using key terms, Na+/H+ exchanger, leukemia, cariporide, and …

lovastatinlcsh:MedicineApoptosisPharmacologyGuanidinesAmiloridep-glycoproteinhemic and lymphatic diseasesDrug InteractionsSulfonesCation Transport ProteinsSodium-Hydrogen Exchanger 1leukemiaMyeloid leukemiaHydrogen-Ion ConcentrationSorafenibUp-RegulationLeukemiaLeukemia Myeloid AcuteImatinib MesylateSignal transductionTyrosine kinasemedicine.drugSignal TransductionSorafenibNiacinamideisoprenylationSodium-Hydrogen Exchangersbcr/ablAntineoplastic AgentsGenes ablGeneral Biochemistry Genetics and Molecular BiologystatinsPatents as TopicCell Line TumorLeukemia Myelogenous Chronic BCR-ABL PositivemedicineHumansProtein Kinase Inhibitorscariporidena+/h+ exchangerTumor hypoxiabusiness.industryPhenylurea Compoundslcsh:ROsmolar Concentrationintracellular phmedicine.diseaseImatinib mesylatefms-Like Tyrosine Kinase 3Fms-Like Tyrosine Kinase 3MutationCancer researchTumor Hypoxiaflt3/itdHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessHeme Oxygenase-1DNA DamageBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
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Osakemarkkinoiden ja reaalitalouden välinen kausaalisuus

1999

makrotaloudelliset muuttujatreaalitalousGranger-kausaalisuusvuorovaikutussuhdeosakemarkkinattehokkaiden markkinoiden hypoteesi
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Petrogrāfiskās un ģeoķīmiskās liecības par Kurzemes batolīta veidošanās apstākļiem

2016

Maģistra darbā ir apkopota, analizēta un interpretēta no dziļurbumu serdēm iegūtā pieejamā informācija par Kurzemes batolīta iežu petrogrāfisko un ģeoķīmisko sastāvu. Pētījuma mērķis ir izveidot hipotēzi par batolīta veidošanās apstākļiem. Pētījumā konstatēts, ka Kurzemes batolīts ir anortozītu – mangerītu – čarnokītu – (rapakivi) granītu komplekss, nevis slāņota tipa mafiska intrūzija. Batolīta iežu sastāvs atbilst toleītu sērijai. Intrūzijas ir veidojis ar Al bagāts kausējums no mantijas. Magmas diferencēšanās procesā galvenā nozīme ir bijusi plagioklāzu kristalizācijai. Batolīta felziskie ieži ir veidojušies no atlikuma magmas ar Zemes garozas iežu kausējuma piejaukumu.

masīvu anortozītirapakivi granītiĢeoloģijatoleītu sērijaAnortozītu – mangerītu – čarnokītu – (rapakivi) granītu komplekssmezoproterozojs
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Experiencing anger in a social interaction: The role of personality

2018

Abstract Although prior research has shown a relationship between the Big Five personality factors and trait anger, evidence that links these personality traits to the experience of state anger is rare. The current study investigated the effect of the Big Five personality traits on the state anger experience after a provocation in a staged social interaction and how status differences moderate these personality effects in an academic sample. In the equal status condition (N = 131, 56% female, aged 18 to 37) participants were provoked by a confederate; in the low status condition (N = 125, 55% female, aged 18 to 51) anger was instead provoked by the experimenter. In both conditions, individu…

media_common.quotation_subject05 social sciences050109 social psychologyAngerbehavioral disciplines and activitiesNeuroticism050105 experimental psychologySocial relationmental disordersbehavior and behavior mechanismsTraitState angerPersonality0501 psychology and cognitive sciencesBig Five personality traitsAnger inPsychologypsychological phenomena and processesGeneral Psychologymedia_commonClinical psychologyPersonality and Individual Differences
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Emotions in Wikipedia: the role of intended negative events in the expression of sadness and anger in online peer production

2018

ABSTRACTThe online encyclopaedia Wikipedia has strict guidelines for ensuring the objectivity of its content and unbiased language of its articles. Wikipedia also provides articles on negative even...

media_common.quotation_subject05 social sciencesGeneral Social Sciences02 engineering and technologyAngerPeer productionHuman-Computer InteractionSadnessArts and Humanities (miscellaneous)Data_GENERAL020204 information systems0502 economics and business0202 electrical engineering electronic engineering information engineeringDevelopmental and Educational PsychologyEncyclopedia050211 marketingAnger inObjectivity (science)PsychologySocial psychologymedia_commonBehaviour & Information Technology
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The power of status: What determines one's reactions to anger in a social situation?

2017

Abstract The present study examined how social status and gender determine anger expression and behavioral reactions toward experienced anger. In two experiments, anger was induced in a staged social interaction. Behavioral anger reactions were judged by observers. In Experiment 1 ( equal status condition ; N  = 110) participants were provoked by a confederate, in Experiment 2 ( low status condition ; N  = 116) participants were provoked by the experimenter. We found that participants expressed their anger to a lesser extent, were less resistant, and engaged in submissive behaviors if they had a lower status than the anger-target. As expected, gender had a moderating effect: While women's a…

media_common.quotation_subject05 social sciencesHuman factors and ergonomicsPoison control050109 social psychologyAngerbehavioral disciplines and activitiesSuicide prevention050105 experimental psychologyOccupational safety and healthSocial relationDevelopmental psychologymental disordersInjury preventionbehavior and behavior mechanisms0501 psychology and cognitive sciencesPsychologypsychological phenomena and processesGeneral PsychologyClinical psychologySocial statusmedia_commonPersonality and Individual Differences
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“Automatic or the People?”

2011

media_common.quotation_subjectApplied psychologyDigital dataAngerPsychologyGeneral Psychologymedia_commonPsychological Science
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