Search results for "anti-p"

showing 5 items of 65 documents

Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells

2013

Molecular targeted therapy has shown promise as a treatment for advanced hepatocellular carcinoma (HCC). Sorafenib, a multikinase inhibitor, recently received FDA approval for the treatment of advanced HCC. However, although sorafenib is well tolerated, concern for its safety has been expressed. Celecoxib (Celebrex®) is a selective cyclooxygenase-2 (COX-2) inhibitor which exhibits antitumor effects in human HCC cells. The present study examined the interaction between celecoxib and sorafenib in two human liver tumor cell lines HepG2 and Huh7. Our data showed that each inhibitor alone reduced cell growth and the combination of celecoxib with sorafenib synergistically inhibited cell growth an…

medicine.medical_treatmentCancer TreatmentGene ExpressionApoptosisPharmacologyBiochemistryTargeted therapy0302 clinical medicineMolecular Cell Biology0303 health sciencesSulfonamidesMultidisciplinaryReverse Transcriptase Polymerase Chain ReactionQLiver NeoplasmsRDrug SynergismGenomicsSorafenib3. Good healthGene Expression Regulation NeoplasticOncology030220 oncology & carcinogenesisMedicineLiver cancermedicine.drugResearch ArticleBiotechnologySignal TransductionSorafenibNiacinamideProgrammed cell deathCarcinoma HepatocellularScienceBlotting WesternBiologyMolecular Genetics03 medical and health sciencesCell Line TumorGastrointestinal TumorsmedicineIn Situ Nick-End LabelingHumansneoplasmsBiology030304 developmental biologyCell ProliferationDNA PrimersHuman liver cancer Apoptosis Sorafenib Celecoxib anti-proliferative effectsCell growthGene Expression ProfilingPhenylurea CompoundsComputational BiologyCancers and NeoplasmsHepatocellular CarcinomaChemotherapy and Drug Treatmentmedicine.diseaseMicroarray Analysisdigestive system diseasesGene expression profilingApoptosisCell cultureCelecoxibPyrazolesGenome Expression AnalysisPLoS ONE
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Role of the N-*(1535) in the J/psi -> pp and J/psi -> p(+)Lambda reactions

2009

We study the J/psi -> p eta p and J/psi -> pK(+)Lambda reactions with a unitary chiral approach. We find that the unitary chiral approach, which generates the N-*(1535) dynamically, can describe the data reasonably well, particularly the ratio of the integrated cross sections. This study provides further support for the unitary chiral description of the N-*(1535). We also discuss some subtle differences between the coupling constants determined from the unitary chiral approach and those determined from phenomenological studies

ratio [width]High Energy Physics::LatticeJ/psi(3100) --> p anti-p etaJ/psi(3100) --> Lambda anti-p K+Físicahadronic decay [J/psi(3100)]coupling constant [N(1535)]mass spectrumwidth [J/psi(3100)]unitarityddc:530chiral [effective Lagrangian]numerical calculations
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Testing the effectiveness of pyrazine defences against spiders

2020

Insects live in a dangerous world and may fall prey to a wide variety of predators, encompassing multiple taxa. As a result, selection may favour defences that are effective against multiple predator types, or target-specific defences that can reduce predation risk from particular groups of predators. Given the variation in sensory systems and hunting tactics, in particular between vertebrate and invertebrate predators, it is not always clear whether defences, such as chemical defences, that are effective against one group will be so against another. Despite this, the majority of research to date has focused on the role of a single predator species when considering the evolution of defended…

spidersaromaattiset yhdisteetchemical defenceanti-predator defencefungihyönteisethämähäkitpyrazinesinsectspuolustusmekanismit (biologia)täpläsiilikäs
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Anti-pluralist arguments in the Tea Party online discourse: A mixed method analysis of populist rhetoric

2022

Populizm może być definiowany jako ideologiczny atrybut partii politycznych, jednak w niniejszym badaniu został on zoperacjonalizowany jako cecha argumentacji, pozwalająca populistom twierdzić, że są oni jedynymi wybrańcami uprawnionymi do reprezentowania interesu narodu. Antypluralistyczne argumenty tego typu wystąpiły w prawicowym dyskursie amerykańskiego ruchu politycznego Tea Party podczas wyborów do amerykańskiego Kongresu w 2018 r. Niniejsze studium przedstawia wyniki analizy oficjalnej strony internetowej Tea Party (treści z zakładki “All News”) przeprowadzonej metodą mieszaną. Wspomagana komputerowo analiza językowa słów kluczowych, konkordancji i sprzężeń (ang. couplings) na próbie…

sprzężenia wyrazowelinguistic couplingretorykarhetoricanti-pluralismTea Partynewsfeedmobilizacjapopulismargumentationantypluralizmpopulizmargumentacjakanał informacyjnymobilizationRes Rhetorica
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The distant present

2013

Introduction, Tuula Vaarakallio & Taru Haapala, 4 Taking Distance as a Condition of the Study of Politics, Kari Palonen, 12 Anti-Parliamentarism of the French Front National Party, Tuula Vaarakallio, 28 The Rhetoric of National Emergency: 9/11 versus Weimar Republic, Anna Kronlund , 48 The Mockery of Adbusters Magazine in the Classical Tradition of Political Rhetoric, Taru Haapala, 71 “Time to be heard”: The Rhetorical Strategies of the Northern Ireland Women’s Coalition, Anna Björk, 90 ‘Dubliners’ in the European Union – A Perspective on the Politics of Asylum-Seeking, Hanna-Mari Kivistö, 106 Notes on Contributors, 129

viestintästrategiatWomen's Coalitionanti-parlamentarismietäännyttäminenhälytystilamaahanmuuttopolitiikkapuolueetretoriikkaAdbusters Magazinekriisiviestintäpilkantekopolitiikantutkimuspoliittinen journalismi9/11poikkeusolotPohjois-IrlantiRanskaturvapaikanhakijat
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