Search results for "antimoni"

showing 10 items of 15 documents

In vitro activity of scorpiand-like azamacrocycle derivatives in promastigotes and intracellular amastigotes of Leishmania infantum and Leishmania br…

2012

The activity of a family scorpiand-like azamacrocycles against Leishmania infantum and Leishmania braziliensis was studied using promastigotes, axenic and intracellular amastigotes forms. All the compounds are more active and less toxic than meglumine antimoniate (Glucantime). Moreover, the data on infection rates and amastigotes showed that compounds P2Py, PN and P3Py are the most active against both species of Leishmania. On the other hand, studies on the inhibitory effect of these compounds on SOD enzymes showed that while the inhibition of the Fe-SOD enzyme of the promastigote forms of the parasites is remarkable, the inhibition of human CuZn-SOD and Mn-SOD from Escherichia coli is negl…

Macrocyclic CompoundsMeglumine antimoniateAntiprotozoal AgentsLeishmania braziliensisMicrobiologyStructure-Activity RelationshipParasitic Sensitivity TestsDrug DiscoverymedicineLeishmania infantumAmastigoteAxenicPharmacologychemistry.chemical_classificationAza CompoundsbiologyDose-Response Relationship DrugMolecular StructureOrganic ChemistryGeneral MedicineLeishmaniabiology.organism_classificationLeishmania braziliensisEnzymechemistryLeishmania infantumIntracellularmedicine.drugEuropean journal of medicinal chemistry
researchProduct

Antimonin määrittämisestä

2008

hybriditantimoniHG-AFSHG-AAS
researchProduct

New binary antimonide Hf5Sb3

1999

Abstract Hf5Sb3 can be prepared by arc-melting of hafnium and previously synthesized HfSb2. It crystallizes like the high-temperature modification of Zr5Sb3 in the Y5Bi3 structure type, space group Pnma, Z=4, a=740.75(9) pm, b=871.8(1) pm, c=1073.6(1) pm, V=693.3(1) 106pm3. An antimonide analogous to the low-temperature form of Zr5Sb3 was not obtained during our investigations. In the structure of Hf5Sb3, the Hf atoms form a three-dimensional network with numerous short Hf–Hf contacts, including the Sb atoms in severely distorted two- and three-capped trigonal prismatic voids. Calculations of the electronic structure, performed with the extended Huckel approximation as well as the TB-LMTO-A…

ChemistryStereochemistryMechanical EngineeringMetals and Alloyschemistry.chemical_elementElectronic structureCrystal structureTrigonal prismatic molecular geometryHafniumCrystallographyTight bindingMechanics of MaterialsGroup (periodic table)AntimonideMaterials ChemistryElectronic band structureJournal of Alloys and Compounds
researchProduct

Numerical study on localized defect modes in two-dimensional lattices: a high Q-resonant cavity

2003

Abstract The spectral widths and the quality factors of defect modes localized for different defects structures formed in a 2D photonic crystal composed of a square lattice of circular rods of indium antimonide (InSb) are theoretically investigated. It is first shown that some factors such as the lattice nature, the line defect orientation, the nature and the defect width have a significant influence on the optical properties of the studied structures and can improve the Q factor and defect peak transmission intensity. Particularly, the transmission spectra of the defects calculated by means the transfer-matrix-method for a particular structure of eight line defects introduced in its center…

FabricationMaterials scienceCondensed matter physicsbusiness.industryIndium antimonideCondensed Matter PhysicsSquare latticeSpectral lineRodElectronic Optical and Magnetic Materialschemistry.chemical_compoundOpticschemistryQ factorLattice (order)Electrical and Electronic EngineeringbusinessPhotonic crystalPhysica B: Condensed Matter
researchProduct

Effects of trans-stilbene and terphenyl compounds on different strains of Leishmania and on cytokines production from infected macrophages.

2017

Most of the antileishmanial modern therapies are not satisfactory due to high toxicity or emergence of resistance and high cost of treatment. Previously, we observed that two compounds of a small library of trans-stilbene and terphenyl derivatives, ST18 and TR4, presented the best activity and safety profiles against Leishmania infantum promastigotes and amastigotes. In the present study we evaluated the effects of ST18 and the TR4 in 6 different species of Leishmania and the modifications induced by these two compounds in the production of 8 different cytokines from infected macrophages. We observed that TR4 was potently active in all Leishmania species tested in the study showing a leishm…

0301 basic medicineTerphenylLeishmaniasiMacrophageMeglumine antimoniatemedicine.medical_treatment030106 microbiologyImmunologyLeishmaniasis CutaneousBiologyMonocytePhagolysosomeMonocytesMicrobiology03 medical and health sciencesInhibitory Concentration 50Terphenyl CompoundsStilbenesmedicineHumansIL-1βAmastigoteCytokineLeishmaniaU937 cellMacrophagesLeishmaniasis CutaneouGeneral MedicineU937 CellsTerphenyl Compoundbiology.organism_classificationLeishmaniaInterleukin 10030104 developmental biologyInfectious DiseasesCytokineIL-1βStilbeneImmunologyIL-10CytokinesParasitologyLeishmania infantumU937 CellIL-18medicine.drugHumanExperimental parasitology
researchProduct

Antimonin biosaatavuus peltolieroille (Aporrectodea tuberculata) ja sitoutuminen lehtimetsämaassa

2008

peltolierotuuttoAporrectodea tuberculataantimonibioakkumulaatiopuolimetallitLumbricidae
researchProduct

ChemInform Abstract: New Binary Antimonide Hf5Sb3 - Differences and Similarities to the Zr Antimonides.

2010

Abstract Hf5Sb3 can be prepared by arc-melting of hafnium and previously synthesized HfSb2. It crystallizes like the high-temperature modification of Zr5Sb3 in the Y5Bi3 structure type, space group Pnma, Z=4, a=740.75(9) pm, b=871.8(1) pm, c=1073.6(1) pm, V=693.3(1) 106pm3. An antimonide analogous to the low-temperature form of Zr5Sb3 was not obtained during our investigations. In the structure of Hf5Sb3, the Hf atoms form a three-dimensional network with numerous short Hf–Hf contacts, including the Sb atoms in severely distorted two- and three-capped trigonal prismatic voids. Calculations of the electronic structure, performed with the extended Huckel approximation as well as the TB-LMTO-A…

chemistry.chemical_elementBinary numberGeneral MedicineElectronic structureStructure typeTrigonal prismatic molecular geometryHafniumMetalCrystallographychemistryGroup (periodic table)visual_artAntimonidevisual_art.visual_art_mediumChemInform
researchProduct

EPIDEMIOLOGICAL SURVEILLANCE OF VISCERAL LEISHMANIASIS IN SICILY, ITALY

1997

Abstract Visceral leishmaniasis (VL) is endemic in Sicily. Although it is a notifiable disease, there is evidence that the actual number of cases is higher than that reported. In 1987, a regional reference center for active surveillance of VL was established and it recorded a total of 284 cases through 1995, a mean of 31.5 cases/year and about four-fold more than previously reported. Of the 284 cases, 150 (53%) were children (≤ 14 years of age), and of the 134 adults, 39 (29%) were coinfected with human immunodeficiency virus (HIV). The commonest viscerotropic zymodeme of Leishmania infantum, MON 1, was identified in 40 (93%) of 43 HIV-negative and eight (57%) of 14 HIV-positive patients. A…

AdultMalemedicine.medical_specialtyAdolescentAllopurinolMeglumine antimoniateNotifiable diseaseAntiprotozoal AgentsHIV InfectionsCohort StudiesAge DistributionMeglumineRecurrenceAmphotericin BVirologyInternal medicineAmphotericin BEpidemiologyOrganometallic CompoundsmedicineAnimalsHumansLeishmania infantumSex DistributionChildSicilyleishmaniasisAgedMeglumine Antimoniatebiologybusiness.industryInfantLeishmaniasisMiddle Agedbiology.organism_classificationmedicine.diseaseSurgeryInfectious DiseasesVisceral leishmaniasisChild PreschoolLeishmaniasis VisceralAntimonialDrug Therapy CombinationFemaleParasitologyLeishmania infantumbusinessmedicine.drug
researchProduct

Low-Temperature Atomic Layer Deposition of High-k SbOx for Thin Film Transistors

2022

SbOx thin films are deposited by atomic layer deposition (ALD) using SbCl5 and Sb(NMe2)3 as antimony reactants and H2O and H2O2 as oxidizers at low temperatures. SbCl5 can react with both oxidizers, while no deposition is found to occur using Sb(NMe2)3 and H2O. For the first time, the reaction mechanism and dielectric properties of ALD-SbOx thin films are systematically studied, which exhibit a high breakdown field of ≈4 MV cm−1 and high areal capacitance ranging from 150 to 200 nF cm−2, corresponding to a dielectric constant ranging from 10 to 13. The ZnO semiconductor layer is integrated into a SbOx dielectric layer, and thin film transistors (TFTs) are successfully fabricated. A TFT with…

ToF-ERDAkylmäfysiikkaantimoniatomic layer depositionoksidittransistorithigh-k dielectriclow temperatureatomikerroskasvatusohutkalvotoxide semiconductor
researchProduct

Leishmaniasis mucocutánea labial, las apariencias pueden engañar.

2019

espanolLa leishmaniasis es una infeccion endemica en nuestro medio. Dentro de sus presentaciones, la forma mucocutanea es la menos frecuente. A pesar de ello se ha de tener en cuenta incluso en casos clinicamente sugestivos de patologia tumoral, como el que presentamos. EnglishLeishmaniasis is an endemic disease in the mediterranean region. Although mucocutaneous presentation is not frequent, we should considerate it in the differential diagnosis of tumoral pathology.

OtorhinolaryngologyLeishmaniasis mucocutáneamiltefosinaSurgeryOral Surgeryantimoniato de megluminaRevista Española de Cirugía Oral y Maxilofacial
researchProduct