Search results for "aorta"

Ascending Aorta Resection and End-to-End Anastomosis: Redistribution of Wall Shear Stress Induced by a Bioprosthetic Heart Valve

2020

Although aortic resection and end-to-end anastomosis are applied to repair ascending aortic aneurysm, there is a lack of information on the late risk of post-operative complications, such as aortic dissection and aneurysmal re-dilatation. It is recognized that altered hemodynamic forces exerted on an aortic wall play an important role on dissection and aneurysm formation. We present a case in which the hemodynamic forces were investigated prior and after repair of an ascending aorta treated by resection with end-to-end anastomosis and a bioprosthetic heart valve. Post-operative wall shear stress was redistributed uniformly along the vessel circumference, and this may suggest a reduced risk …

A clampless and sutureless aortic anastomosis technique using an endograft connector for aortoiliac occlusive disease in which the aorta cannot be cl…

2012

Bypass surgery in aortoiliac or aortofemoral occlusive disease can be technically demanding and hazardous due to huge calcifications and/or patient co-morbidities. We report about mid-term results of a telescoping sutureless aortic anastomosis technique using endografts as connectors to address such challenging situations. This is a single-center experience (2004–2011) in seven patients (63 ± 6 years) requiring aortoiliac (three) or aortofemoral (four) bypass surgery. In six cases, an aortic stent graft was telescoped into the infrarenal aorta and partly deployed within the aorta and partly outside the aorta. In the first case, a bifurcated stent graft was deployed and the iliac legs were p…

Tips and tricks to make the ascending aorta accessible to EVAR

2012

The ascending aorta is gaining increasing interest for endovascular specialists, as it opens the door to a potentially better way to treat aortic arch pathologies. Landing safely a stentgraft into the ascending aorta allows downgrading significantly the invasiveness of conventional open repair of the ascending aorta and/or aortic arch. Unfortunately, accessibility to the ascending aorta, in order to perform EVAR, can be challenging as the transfemoral approach might be cumbersome, or because the ascending aorta might not be appropriate for stentgraft landing. This paper will present some technical tips and tricks to achieve successful stentgraft landing in zone 0.

Post-operative computed tomography imaging evaluation of ascending aorta surgery

2021

Ascending thoracic aorta disease is often a life-threatening condition. Aortic aneurysm and aortic dissection are the most frequent ascending aorta diseases requiring surgical intervention. Surgical repair techniques of the ascending aorta are various; they include reconstruction of the ascending aorta by using a graft with or without a prosthetic valve, reconstruction with a composite artificial graft or using a biological graft, and reconstruction of the ascending aorta with a composite graft preserving the native valve and arch repair. The radiologist plays a key role in the identification of post-operative complications; differentiation from normal postoperative findings is fundamental.…

Estudio de miRNAs en la formación de aneurismas de aorta abdominal en humanos

2021

Los microRNA (miRNAs/miRs) son pequeñas cadenas de ácido ribonucleico (ARN, del inglés RNA) que regulan diferentes procesos biológicos. El objetivo de este estudio consistió en identificar miRNAs alterados en plasma y tejido de pacientes con aneurismas de aorta abdominal (AAA) y explorar nuevas dianas potencialmente involucradas en su desarrollo. Cincuenta y siete sujetos fueron reclutados para el estudio en plasma (30 pacientes con AAA, 16 voluntarios sanos y 11 paciente con arterioesclerosis). Se testó el nivel de expresión de 179 miRNAs en un subgrupo de las muestras de plasma y, posteriormente, se validaron los miRNAs disregulados en la población completa. Los miRNA alterados también se…

Multifibrillar bundles of a self-assembling hyaluronic acid derivative obtained through a microfluidic technique for aortic smooth muscle cell orient…

2018

A hyaluronic acid derivative that is able to physically crosslink in a saline aqueous environment was employed for the production of fibers with a mean diameter of 50 μm using a microfluidic technique. The microfibers were collected in a tailored rotating collector and assembled to form multifibrillar bundles. The orientation of the microfibers on the collected bundles was evaluated by microCT analysis. The bundles were biofunctionalized by physical addition of fibronectin or chemical tethering of a cyRGDC peptide to achieve control of Aortic Smooth Muscle Cell (AoSMC) attachment, elongation and alignment. The mechanical performances of these bundles were evaluated by elongation tests, rela…

INTERACTION BETWEEN SODIUM NITRITE AND BETA ADRENERGIC BLOCKERS ON ISOLATED RAT AORTA

1978

Relationship of choroidal thickness with pulsatile hemodynamics in essential hypertensive patients

2021

Controversy exists about the association of choroidal thickness (CTh) with blood pressure (BP) values. There is some evidence suggesting that central hemodynamics changes are associated with microvascular disease. Our study was aimed to assess the relationships between CTh and clinic and 24-h BP and between CTh and estimated 24-h aortic pulse pressure (aPP), 24-h aortic systolic BP (aSBP), and 24-h aortic augmentation index (aAIx) in a group of hypertensive patients. We enrolled 158 hypertensive subjects (mean age 48 ± 13 years) all of which underwent evaluation of the choroidal district by Swept-Source optical coherence tomography (SS-OCT) and 24-h BP monitoring, in order to measure periph…

Zator tętnicy środkowej siatkówki jako pierwsza manifestacja kliniczna w postaci powikłania zatorowo-zakrzepowego jednopłatkowej zastawki aortalnej—o…

2018

Jednopłatkowa zastawka aortalna (UAV) jest rzadką wrodzoną wadą zastawki aortalnej. Przegląd literatury sugeruje, że szacowana częstość jej występowania wynosi 0,02%. W artykule przedstawiono przypadek 40-letniego pacjenta z UAV z ciężką stenozą. Etiologia jednopłatkowej zastawki aortalnej jest najczęściej wrodzona, jednak w opisanym przypadku rozpatruje się ją na dwóch możliwych podłożach — jako wadę wrodzoną o podtypie slit-shaped unicomissural lub jako wadę nabytą o degeneracyjnej postaci zwężenia zastawki. Pierwszą manifestacją choroby u pacjenta było powikłanie zakrzepowo-zatorowe w postaci zatoru tętnicy środkowej siatkówki objawiające się nagłym zaniewidzeniem. Chorego skierowano na …

A Non-Local Mode-I Cohesive Model for Ascending Thoracic Aorta Dissections (ATAD)

2018

This paper presents a non-local interface mechanical model to describe aortic dissection. In this regard, the mode-I debonding problem based on a cohesive zone modeling is endowed with non-local terms to include long-range interactions that are present in multi-layered biological tissue. Such non-local effects are related to the collagen fibers that transmit forces between non-adjacent elements. Numerical simulations are provided with different values of the non-local parameters in order to show the effect of the non-locality during the debonding processes.