Search results for "arco"
showing 10 items of 1716 documents
[Protein intake in community-dwelling postmenopausal women and its relationship with sarcopenia].
2021
Objectives: the general aging of the population is related to the increase in the prevalence of sarcopenic disease; especially among older women, this pathology is closely related to nutrition and specifically to protein consumption in older adults. The aim of our study was to evaluate the possible relationship between a low protein intake and a higher prevalence of sarcopenic disease, a worse dietary pattern, and lower physical performance in postmenopausal women living in the community. Material and methods: the study was carried out in a total of 164 independent women over 65 years of age, recruited from a municipal social center in Valencia (Benimaclet). The presence of sarcopenic patho…
MALNUTRITION IS ASSOCIATED WITH DEPRESSION IN LONG-TERM CARE POPULATION
2018
Rationale: Frailty in elderly is a multifactorial syndrome and is associatet with an increased risk of poor health outcomes (falls, disability, hospital- ization and mortality), malnutrition and depression are the must impor- tant factors contributing to frailty. This study describes the application of multidimensional evaluation for the early identification of frailty in long- term care population.Methods: Clinical data from 100 long-term care inpatients (53 female and 47 male, mean age 69.6 years) were collected at the ARNAS Civico- DiCristina-Benfratelli, Palermo, Italy. Each inpatient had undergone a multidimensional assessment through a multiprofessional team. Nutri- tional state was a…
Effect of Calcifediol on Physical Performance and Muscle Strength Parameters: A Systematic Review and Meta-Analysis
2022
There is general agreement that optimal vitamin D status is necessary for bones, muscles, and general health, particularly in older adults, who are at higher risk of negative consequences of vitamin D deficiency, including sarcopenia; vitamin D supplementation is proposed as a potential intervention to mitigate sarcopenia. Several RCTs have reported that calcifediol (25(OH)D) was more potent than cholecalciferol in increasing plasma 25(OH)D. The present systematic review and meta-analysis aimed to summarize the effects of calcifediol on physical performance and muscle strength. We searched databases from inception to 1 January 2022 for studies investigating calcifediol on physical performan…
Factors contributing to the variability in muscle ageing
2012
a b s t r a c t Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbing stairs. The rate of structural and functional deterioration of muscle appears to vary considerably between people. Part of the variation in the 'rate of muscle ageing' is attributable to genetic factors, the timing of changes in circulating hormones and the presence or absence of chronic low-grade systemic inflammation. Where an individual cannot change much i…
Inactivity-induced oxidative stress: A central role in age-related sarcopenia?
2012
Ageing causes a progressive decline in skeletal muscle mass that may lead to decreased strength and functionality. The term sarcopenia is especially used to characterise this geriatric syndrome. Numerous conditions and behaviours are considered to accelerate the progression of sarcopenia such as chronic diseases, malnutrition and physical inactivity. As people in modern countries are more and more sedentary, the impact of physical inactivity on the prevalence of sarcopenia might be more and more important in the future. In this review, we discuss how reactive oxygen species (ROS) could mediate the effects of lifelong inactivity in the onset and progression of age-related sarcopenia. Althoug…
Muscle and bone mass in middle‐aged women : role of menopausal status and physical activity
2020
Background. Women experience drastic hormonal changes during midlife due to the menopausal transition. Menopausal hormonal changes are known to lead to bone loss and potentially also to loss of lean mass. The loss of muscle and bone tissue coincide due to the functional relationship and interaction between these tissues. If and how physical activity counteracts deterioration in muscle and bone during the menopausal transition remains partly unresolved. This study investigated differences between premenopausal, early perimenopausal, late perimenopausal, and postmenopausal women in appendicular lean mass (ALM), appendicular lean mass index (ALMI), femoral neck bone mineral density (BMD) and T…
Seed germination in Sarcopoterium spinosum (L.) Spach from South-Eastern Sicily
2012
Sarcopoterium spinosum (L.) Spach is a nanophanerophyte whose presence in Sicily is limited to the South-East of the island. A study on seed germination behaviour of seeds collected from some populations indicates low viability of seedlings which could seriously put the long-term survival of these populations at risk.
A new species of Strunius(Sarcopterygii; Onychodontida) from Latvia; Lode quarry (Upper Devonian)
1995
Abstract A new species of the genus Strunius has been found. It is distinct from the other Strunius species; S. rolandi and S. walteri in the shape of the gular and parasymphysial teeth. The sigmoid tooth tips are harpoon-shaped and are similar to those of Onychodus jaekeli. Strunius nov. sp. is more closely related to S. rolandi than to the type-species S. walteri.
Towards sarcosine determination in urine for prostatic carcinoma detection
2019
Abstract Sarcosine, a potential biomarker for prostate cancer, can be detected in a solid state enzyme based biosensor using sarcosine oxidase, with particle immobilised reagents. A novel fusion protein of the fluorescent protein, mCherry, sarcosine oxidase (SOx), and the polypeptide R5 (R52-mCherry-SOx-R5-6 H), was explored, which allowed self-immobilization on silica microparticles and long-term (90 days +) retention of activity, even at room temperature. In contrast, commercial wildtype SOx lost activity in a few days. A silica-R52-mCherry-SOx-R5-6H microparticle sensor for determination of sarcosine in urine, linked the SOx coproduct, H2O2, to a measurement catalysed by horseradish pero…
A head-to-head comparison of poly(sarcosine) and poly(ethylene glycol) in peptidic, amphiphilic block copolymers
2015
Abstract In this work we compare chemical and solution properties, like critical aggregate concentrations (CAC) and hydrodynamic radii of aggregates based on either poly(ethylene glycol) or poly(sarcosine) block copolymers in aqueous solution. The amine functionalized, hydrophilic polymers poly(sarcosine) (degree of polymerization, X n = 100 and 200) and PEG (X n = 121 and 242) of comparable hydrodynamic volume were used to initiate the ring opening polymerization of α-amino acid- N -carboxyanhydrides based on ɣ-benzyl- l -glutamate (Glu(OBn)) or e-carboxybenzyl- l -lysine (Lys(Z)). The second, hydrophobic block was kept at a degree of polymerization of 25 and 50 to enable a direct compar…