Search results for "arco"
showing 10 items of 1716 documents
Die Reaktion von 2-Halogenethoxycarbonyl-Verbindungen mit tertiären Phosphanen
1979
(2-Bromethoxycarbonyl)aminosauren 1, einschlieslich der Sarkosin-Derivate 13 und 15, reagieren mit Methyldiphenylphosphan zu den 2-Phosphonioethoxycarbonyl-Verbindungen, welche unter milden basischen Bedingungen zu den freien Aminoverbindungen gespalten werden. Die gleiche Schutzgruppenumwandlung gelingt an 2-Bromethoxycarbonyl-geschutzten Alkoholen 3. Phenolen 4 und den sekundaren Aminen 11 und 12 sowie an Aminosaure- und Peptid-(2-bromethylestern) nicht. In diesen Fallen bildet sich das Ethylen-1,2-bisphosphoniumsalz 6. Reaction of 2-Haloethoxycarbonyl Compounds with Tertiary Phosphanes (2-Bromoethoxycarbonyl)amino acids 1 including the sarcosine derivatives 13 and 15 react with methyldip…
Assessing the effect of chromium pollution on benthic foraminiferal community: morphological vs. environmental metabarcoding approaches
The purpose of this experimental study is to assess the impact of different concentrations of chromium (Cr) through time on the diversity of cultured benthic foraminifera combining two morphological approaches for the identification of living specimens that are Rose Bengal (RB) staining and CellTracker Green (CTG) labelling as well as environmental DNA and RNA metabarcoding. Seven tanks/aquaria with different concentrations of Cr in water, namely 100 ppt, 1 ppb, 10 ppb, 100 ppb, 1 ppm and 10 ppm plus the control were used. A mesocosm was extracted from each tank at pre-established time (1 week, 2 weeks, 4 weeks 6 weeks and 8 weeks). Morphological analyses produced 6 datasets based on staini…
Dermatofibrosarcoma protuberans: estudio de factores pronósticos
2012
Introducción: El dermatofibrosarcoma protubernas (DFSP) es un tumor cutáneo de malignidad intermedia clasificado dentro de los tumores fibrohistiocíticos que tiene una alta tasa de recidivas locales tras extirpaciones con cirugía convencional pero baja capacidad de producir metástasis. Hipótesis: Existen determinadas características del DFSP que condicionan un crecimiento más infiltrativo, asimétrico e impredecible, lo que supone mayor morbilidad para el paciente y una mayor dificultad para su tratamiento. Objetivos: 1.-Realizar un análisis observacional y descriptivo de una serie de casos de DFSP que han sido vistos en el Servicio de Dermatología del IVO, según las características epidemio…
Oreto! ... Oreto!, Spazio! Spazio!
2008
Descrive il rapporto tra il fiume Oreto e la città di Palermo. I riferimenti sono alla possibilità dell'istituzione del Parco dell'Oreto. Si descrive un percorso che conduce ad un rapporto creativo tra arte, aree sensibili e città.
La città universitaria di Palermo e le connessioni con il parco d'Orléans
2008
L'articolo percorre brevemente la storia della genesi della città universitaria di Palermo, costruita, a partire dagli anni Cinquanta del Novecento, sulla particolare preesistenza dell'ottocentesco parco d'Orléans.
Implantación de un procedimiento para la atención de menores en situación de riesgo en el municipio de Gandia: 'Un reto para la consecución de Buenas…
2011
El marco jurídico vigente en materia de protección de menores define las competencias de los Servicios Sociales Municipales en la prevención, detección e intervención en todos aquellos casos en que existan menores de 18 años, que se encuentren en situación de Dificultad Social (riesgo leve), Desprotección (riesgo moderado, grave y desamparo) y/o Conflicto Social. La práctica diaria y la complejidad en la atención al usuario y/o familia, hacen necesaria la elaboración de circuitos y el desarrollo secuencial del proceso que se pretende llevar a cabo desde cualquier servicio o programa. Por lo tanto, el manual de procedimiento de atención a menores en situación de riesgo consiste en un documen…
La Comunicazione nel Parco delle Madonie. Un Piano per lo sviluppo turistico, economico, socio-culturale
2009
Absence of mutation at the GAP-related domain of the neurofibromatosis type 1 gene in sporadic neurofibrosarcomas and other bone and soft tissue sarc…
1995
The NF1 gene encodes neurofibromin, a GTPase-activating protein containing a GAP-related domain (NF1-GRD) that is capable of downregulating ras by stimulating ras intrinsic GTPase activity. We tested 44 sarcomas, nine of which corresponded to sporadic neurofibrosarcomas, for mutations at the NF1-GRD by the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique, finding no mutation in every sample tested. We suggest that inactivation of the NF1-GRD by gene mutation seems not to be an important event in the tumorigenesis of sarcomas.
Bleomycin: Action on growth of oncogenic RNA viruses and on cell transformation
1975
Bleomycin (BLM) inhibits cell proliferation of noninfected chick embryo fibroblasts by blocking their DNA synthesis selectively. Chick embryo fibroblasts have beentransformed by Schmidt-Ruppin D strain of Rous Sarcoma Virus. Transformation has been determined by a focus assay. Foci formation is strongly reduced by BLM. Virus replication is inhibited by BLM in growing and confluent monolayer cells. This result might be explained by the observation that this drug reduces proliferation of growing and of confluent monolayer cells very sensitively. During the first 24 hours after infection the BLM inhibitory effect is more pronounced than in the case of BLM-application during the period 24--48 h…
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation
2008
The Werner syndrome helicase/3′-exonuclease (WRN) is a major component of the DNA repair and replication machinery. To analyze whether WRN is involved in the repair of topoisomerase-induced DNA damage we utilized U2-OS cells, in which WRN is stably down-regulated (wrn-kd), and the corresponding wild-type cells (wrn-wt). We show that cells not expressing WRN are hypersensitive to the toxic effect of the topoisomerase I inhibitor topotecan, but not to the topoisomerase II inhibitor etoposide. This was shown by mass survival assays, colony formation and induction of apoptosis. Upon topotecan treatment WRN deficient cells showed enhanced DNA replication inhibition and S-phase arrest, whereas af…