Search results for "arki"
showing 10 items of 1015 documents
Insidious onset of Pisa syndrome after rasagiline therapy in a patient with Parkinson’s disease
2014
N.A.
Reversible Pisa Syndrome in a patient with Parkinson's disease on rasagiline therapy
2013
Benchmarking Spain's Biotechnology: a comparative perspective
2010
Economic and Technical Efficiency of Drinking Water Systems: An Empirical Approach for Spain
2009
The objective of this paper is to analyze the efficiency of drinking water systems. Efficient performance, both in technical and economic terms guarantee minimum water losses in the network and reduced tariffs for the users. An analytical benchmarking methodology based on non-radial measures considering water losses as undesirable output gives us an efficiency indicator for each input used in the water supply process. These indicators, obtained by means of mathematical programming techniques, are used to rank suppliers' activity. The relation between the efficiency in the activity of the companies and the establishment of different tariffs is also analyzed. An empirical application is carry…
Assessment of building energy modelling studies to meet the requirements of the new Energy Performance of Buildings Directive
2020
Abstract The cost optimal method (COM) as applied in the Energy Performance of Buildings Directive (EPBD) uses “non-calibrated deterministic reference buildings (RBs)”. Such RBs are defined with single envelope and equipment parameter values, for which calibration with actual building stock energy performance (EP) is not undertaken. Thus, it is not possible to visualise the effect of uncertainties or diversity in the input parameters on cost-optimal level benchmarks and to verify the choice of RBs. The paper proposes an update to the COM via use of “Probabilistic Bayesian calibrated RBs” to handle uncertainties and produce more realistic cost optimal levels to support policy makers in devis…
A European Observational Study to Evaluate the Safety and the Effectiveness of Safinamide in Routine Clinical Practice: The SYNAPSES Trial
2021
Background: Safinamide modulates both dopaminergic and glutamatergic systems with positive effects on motor and non-motor symptoms of Parkinson's disease (PD). The drug utilization study SYNAPSES was designed to investigate the use of safinamide in routine clinical practice, as recommended by the European Medicines Agency. Objective: To describe the occurrence of adverse events in PD patients treated with safinamide in real-life conditions. Methods: The SYNAPSES trial is an observational, European, multicenter, retrospective-prospective cohort study. Patients were followed up to 12 months with analyses performed in the overall population and in patients aged >75 years, with relevant comorbi…
Parkinsonian Patients with Deficits in the Dysexecutive Spectrum are Impaired on Theory of Mind Tasks
2013
Understanding the mental states of others entails a number of cognitive processes known as Theory of Mind (ToM). A relationship between ToM deficits and executive disorders has been hypothesized in individuals with Parkinson's disease (PD). The present study was aimed at investigating the effect of dysexecutive deficits on ToM abilities in PD patients without dementia. Participants included 30 PD patients and 30 healthy subjects (HC). PD patients were divided into two groups according to their executive test performance: patients with poor (dysexecutive group; n = 15) and normal (executively unimpaired group; n = 15) performance. All participants were administered faux pas recognition writt…
Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies
2017
[Background] The objective of this study will be to synthesize the epidemiological evidence and evaluate the validity of the associations between central nervous system disorders and the risk of developing or dying from cancer.