Search results for "arvo"
showing 10 items of 2138 documents
Concepts to Reveal Parvovirus–Nucleus Interactions
2021
Parvoviruses are small single-stranded (ss) DNA viruses, which replicate in the nucleoplasm and affect both the structure and function of the nucleus. The nuclear stage of the parvovirus life cycle starts at the nuclear entry of incoming capsids and culminates in the successful passage of progeny capsids out of the nucleus. In this review, we will present past, current, and future microscopy and biochemical techniques and demonstrate their potential in revealing the dynamics and molecular interactions in the intranuclear processes of parvovirus infection. In particular, a number of advanced techniques will be presented for the detection of infection-induced changes, such as DNA modification…
Chi Zijian: Puolikuu
2022
Kirja-arvostelu teoksesta Chi, Z. & Sainio, R. k. (2022). Puolikuu. Aula & Co. nonPeerReviewed
Inger Christensen: Alfabet
2021
Kirja-arvostelu teoksesta Inger Christensen, Alfabet, suom. Oscar Rossi, Poesia 2021 nonPeerReviewed
Hume’s guillotine and intelligent technologies
2021
AbstractEmerging intelligent society shall change the way people are organised around their work and consequently also as a society. One approach to investigating intelligent systems and their social influence is information processing. Intelligence is information processing. However, factual and ethical information are different. Facts concern true vs. false, while ethics is about what should be done. David Hume recognised a fundamental problem in this respect, which is that facts can be used to derive values. His answer was negative, which is critical for developing intelligent ethical technologies. Hume’s problem is not crucial when values can be assigned to technologies, i.e. weak ethic…
Harnessing User Values to Understand Value Co-Creation and Co-Destruction in Augmented Reality Mobile Games
2021
This paper explores the phenomena of value co- creation and co-destruction in augmented reality (AR) mobile games. More specifically, we aim to achieve an in-depth understanding of value co-creation and co- destruction occurring in Pokémon GO and the user values underlying these occurrences. Service-dominant (S-D) logic provides our study with a lens for understanding users as active co-creators, co- destroyers, and determinants of value. Further, the means-end theory establishes users’ personal values and goals as the basis for service value determination. We uncover key values highlighted in users’ positive and negative gaming experiences through a qualitative content analysis of 43 in-de…
Eettisen arvotietoisuutemme kehittymisestä
2010
EETTISEN ARVOTIETOISUUTEMME KEHITTYMISESTÄ Samppa Koivula Filosofia/maisteriohjelma Pro gradu-tutkielma Yhteiskuntatieteiden ja filosofian laitos Jyväskylän yliopisto Ohjaaja: Jussi Kotkavirta Lokakuu 2010 124 sivua Tämän tutkielman tavoitteena on ollut kuvata ihmisen eettisen arvotietoisuuden kehittymisen prosessia yksilön näkökulmasta. Tutkielman teoreettisena pääviitekehyksenä on käytetty Platonin teoriaa ihmissielun kolmesta tasosta. Tähän pääviitekehykseen liittyen, yksilön näkökulman vahvistamiseksi, on peilattu André Comte-Sponvillen teoriaa rakkauden kolmestatasosta. Kontrastin luomiseksi on myös tarkasteltu muutamia sellaisia filosofeja (Aristoteles,Nietzsche) ja aatesuuntia (Freud…
Dynamics and interactions of parvoviral NS1 protein in the nucleus
2007
Summary Nuclear positioning and dynamic interactions of viral proteins with nuclear substructures play essen- tial roles during infection with DNA viruses. Visual- ization of the intranuclear interactions and motility of the parvovirus replication protein (NS1) in living cells gives insight into specific parvovirus protein- cellular structure interactions. Confocal analysis of highly synchronized infected Norden Laboratory Feline Kidney cells showed accumulation of nuclear NS1 in discrete interchromosomal foci. NS1 fused with enhanced yellow fluorescence protein (NS1- EYFP) provided a marker in live cells for dynamics of NS1 traced by photobleaching techniques. Fluo- rescence Recovery after…
Potential for cascading impacts of environmental change and policy on indigenous culture.
2022
AbstractGlobal environmental and societal changes threaten the cultures of indigenous peoples and local communities (IPLC). Despite the importance of IPLC worldviews and knowledge to sustaining human well-being and biodiversity, risks to these cultural resources are commonly neglected in environmental governance, in part because impacts can be indirect and therefore difficult to evaluate. Here, we investigate the connectivity of values associated with the relationship Ngātiwai (a New Zealand Māori tribe) have with their environment. We show that mapping the architecture of values-environment relationships enables assessment of how deep into culture the impacts of environmental change or pol…
Dynamic analysis for axially moving viscoelastic panels
2012
In this study, stability and dynamic behaviour of axially moving viscoelastic panels are investigated with the help of the classical modal analysis. We use the flat panel theory combined with the Kelvin–Voigt viscoelastic constitutive model, and we include the material derivative in the viscoelastic relations. Complex eigenvalues for the moving viscoelastic panel are studied with respect to the panel velocity, and the corresponding eigenfunctions are found using central finite differences. The governing equation for the transverse displacement of the panel is of fifth order in space, and thus five boundary conditions are set for the problem. The fifth condition is derived and set at the in-…
LR-NIMBUS : an interactive algorithm for uncertain multiobjective optimization with lightly robust efficient solutions
2022
In this paper, we develop an interactive algorithm to support a decision maker to find a most preferred lightly robust efficient solution when solving uncertain multiobjective optimization problems. It extends the interactive NIMBUS method. The main idea underlying the designed algorithm, called LR-NIMBUS, is to ask the decision maker for a most acceptable (typical) scenario, find an efficient solution for this scenario satisfying the decision maker, and then apply the derived efficient solution to generate a lightly robust efficient solution. The preferences of the decision maker are incorporated through classifying the objective functions. A lightly robust efficient solution is generated …