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showing 10 items of 31559 documents
Epidemiología y Control de la Enfermedad de Chagas en el Departamento de Cochabamba (Bolivia).
2015
La enfermedad de Chagas es uno de los problemas más graves de salud pública que afectan a América Latina; históricamente extensas áreas de Bolivia han registrado la mayor prevalencia de la infección por su agente causal, el protozoo Trypanosoma cruzi. A principios del año 2000, en este país se puso en marcha un programa de control vectorial, que consistió en el rociado masivo de viviendas con insecticidas piretroides, instaurado para controlar la infestación de viviendas por los insectos hematófagos que transmiten la enfermedad. En este trabajo se proporciona una evaluación detallada de los efectos de este programa en el Departamento de Cochabamba, uno de los lugares más endémico de todo el…
Atomic layer deposition of localised boron- and hydrogen-doped aluminium oxide using trimethyl borate as a dopant precursor
2020
Atomic layer deposition (ALD) of boron-containing films has been mainly studied for use in 2D materials and for B-doping of Si. Furthermore, lithium-containing borates show great promise as solid electrolyte coatings for enhanced energy storage. In this work, we examine trimethyl borate (TMB) and triethyl borate (TEB) in combination with O2 plasma as precursors for ALD of B-containing films, targeting the growth of B2O3. It is found that films grown from TEB contain no boron. Further work with TMB as a boron-containing precursor showed promising initial growth on a SiO2 or Al2O3 surface, but a rapid decrease of the growth rate during subsequent ALD cycles indicating surface inhibition durin…
Targeting the Activin Receptor Signaling to Counteract the Multi-Systemic Complications of Cancer and Its Treatments
2021
Muscle wasting, i.e., cachexia, frequently occurs in cancer and associates with poor prognosis and increased morbidity and mortality. Anticancer treatments have also been shown to contribute to sustainment or exacerbation of cachexia, thus affecting quality of life and overall survival in cancer patients. Pre-clinical studies have shown that blocking activin receptor type 2 (ACVR2) or its ligands and their downstream signaling can preserve muscle mass in rodents bearing experimental cancers, as well as in chemotherapy-treated animals. In tumor-bearing mice, the prevention of skeletal and respiratory muscle wasting was also associated with improved survival. However, the definitive proof tha…
Mast cells as protectors of health.
2019
Mast cells (MCs), which are well known for their effector functions in T(H)2-skewed allergic and also autoimmune inflammation, have become increasingly acknowledged for their role in protection of health. It is now clear that they are also key modulators of immune responses at interface organs, such as the skin or gut. MCs can prime tissues for adequate inflammatory responses and cooperate with dendritic cells in T-cell activation. They also regulate harmful immune responses in trauma and help to successfully orchestrate pregnancy. This review focuses on the beneficial effects of MCs on tissue homeostasis and elimination of toxins or venoms. MCs can enhance pathogen clearance in many bacter…
HPLC/HRMS and GC/MS for Triacylglycerols Characterization of Tuna Fish Oils Obtained from Green Extraction
2023
Background: Fish oil is one of the most common lipidic substances that is consumed as a dietary supplement. The high omega-3 fatty acid content in fish oil is responsible for its numerous health benefits. Fish species such as mackerel, herring, tuna, and salmon are particularly rich in these lipids, which contain two essential omega-3 fatty acids, known as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Objectives: Due to the scarcity of information in the literature, this study aimed to conduct a qualitative and quantitative characterization of triglycerides (TAGs) in crude tuna fish oil using HPLC/HRMS. Fatty acid (FA) determination was also performed using GC/MS. The tuna fis…
High-Sensitivity Whispering Gallery Mode Humidity Sensor Based on Glycerol Microdroplet Volumetric Expansion
2021
We demonstrate a highly sensitive whispering gallery mode (WGM) relative humidity (RH) sensor based on a glycerol microdroplet. WGMs were excited using a 760 nm tunable semiconductor laser. We used free space coupling, which is effective when using a liquid resonator. A detailed analysis of different parameters influencing the sensor’s characteristics (sensitivity, hysteresis, resolution, stability, and temperature) is presented. The sensitivity of the sensor is one of the highest reported (2.85 nm/% RH in the range 50–70% RH with the resolution 1 × 10−4% RH). This type of humidity sensor has several advantages, such as high sensitivity, extended lifetime, good repeatability, and low cost, …
Understanding tungsten erosion during inter/intra-ELM periods in He-dominated JET-ILW plasmas
2021
Tungsten erosion was quantified during inter/intra-ELM periods in He-dominated JET-ILW plasmas by optical emission spectroscopy. The intra-ELM tungsten sputtering in helium plasmas, which dominates the total W source, prevails by a factor of about 4 over inter-ELM sputtering in the investigated ELM frequency range from 90 Hz-120 Hz. He ions are mainly responsible for the W erosion during the ELMs in He plasmas. The strong in/out asymmetry of the ELM-induced W erosion is observed in He plasmas even at high ELM frequencies beyond 100 Hz. In Ohmic/L-mode plasmas and during the H-mode inter-ELM plasma phases both He2+ and Be2+ ionic species are major contributors to the W erosion. Their contrib…
Strictly correlated electrons approach to excitation energies of dissociating molecules
2019
In this work we consider a numerically solvable model of a two-electron diatomic molecule to study a recently proposed approximation based on the density functional theory of so-called strictly correlated electrons (SCE). We map out the full two-particle wave function for a wide range of bond distances and interaction strengths and obtain analytic results for the two-particle states and eigenenergies in various limits of strong and weak interactions, and in the limit of large bond distance. We then study the so-called Hartree-exchange-correlation (Hxc) kernel of time-dependent density functional theory which is a key ingredient in calculating excitation energies. We study an approximation b…
A Computationally Efficient Online/Offline Signature Scheme for Underwater Wireless Sensor Networks
2022
Underwater wireless sensor networks (UWSNs) have emerged as the most widely used wireless network infrastructure in many applications. Sensing nodes are frequently deployed in hostile aquatic environments in order to collect data on resources that are severely limited in terms of transmission time and bandwidth. Since underwater information is very sensitive and unique, the authentication of users is very important to access the data and information. UWSNs have unique communication and computation needs that are not met by the existing digital signature techniques. As a result, a lightweight signature scheme is required to meet the communication and computation requirements. In this researc…
Outcome Analysis From a Multicenter Registry on Unibody Stent-Graft System for the Treatment of Spontaneous Infrarenal Acute Aortic Syndrome (MURUSSI…
2022
Purpose: This study reports the outcomes from a Multicenter Registry on unibody stent-graft system for the treatment of spontaneous infrarenal acute aortic syndrome (MURUSSIAS registry). Materials and methods: The retrospective MURUSSIAS registry included spontaneous infrarenal acute aortic dissection (IAAS) managed with the unibody stent-graft system (AFX endovascular AAA system; Endologix Inc., Irvine, California) outside the current instruction for use. IAAS considered aortic dissection (AD), intramural hematoma (IMH), and penetrating aortic ulcer (PAU). Indications to IAAS treatment were symptoms, associated dilated abdominal aorta (>3 cm), rapidly-growing (>0.5 cm/6 months) aorta…