Search results for "axis"
showing 10 items of 751 documents
La valoración del Practicum en la formación inicial: un estudio de casos internacional en el área de Geografía e Historia
2020
El acceso a la función docente es asunto regulado por las instituciones administrativas, pero depende en gran medida de las competencias, actitudes y expectativas personales. Los estudios comparativos que mostramos revelan que las representaciones sociales que determinan un sentido práctico del saber escolar inciden en las opiniones de los actuales profesores de Secundaria y en los que aspiran a serlo. Este fenómeno subjetivo, que incide en las competencias profesionales, se interpreta cualitativamente con una metodología de casos, con la comparación de estos a partir de las encuestas y memorias del Practicum en tres universidades de Brasil, Colombia y España. El análisis sobre objetivos y …
Identity tensions in dual career : the discursive construction of future selves by female Finnish judo athletes
2019
To date, few studies have explored how changes in the practices, policies, and politics of sport and education may be implicated in how young athletes think about and plan for the future. Drawing on cultural praxis and feminist poststructuralist frameworks, this paper explores whether and how dual career (DC) policies and practices in Finland guide female judo athletes’ imaginings about their future. Discourse analysis was used to analyse interviews with three adolescent (aged 16) and three young adult (aged 20, 23, and 27) elite female judo athletes. Differences were found in the ways the athletes in the different age groups constructed their future athletic, civic and gendered selves. We …
Composite vignettes of Swedish male and female professional handball players’ career paths
2019
The aim of this study was to describe gender-specific career paths of Swedish professional handball players. A reanalysis of Ekengren et al. (2018) career interviews with nine male and nine female players led to creating two composite vignettes using the athletes’ own words, accounted for typical features in the male and female players’ career paths. Seven themes were identified in the analysis of the men’s transcripts and eight themes derived from the women’s transcripts. Further, the themes of both vignettes were aligned with career stages described in our previous study (Ekengren et al. 2018). The male players’ vignette is interpreted as a performance narrative congruent with elite handb…
Critical educational praxis in university ecosystems: enablers and constraints
2018
Universities serve several important functions in society today through research, education, and community engagement, not least helping people to live meaningfully in society, and helping to create a world worth living in. A kind of practice that seems particularly important in fulfilling such responsibilities is critical educational praxis, a social-justice oriented, educational practice/praxis, with a focus on asking critical questions and creating conditions for positive change. Yet, the contemporary university is not exactly a niche for critical educational praxis. There are many practices and arrangements within higher education that make the enactment of critical educational praxis v…
This can be made more student-centred : Asynchronous mediation in in-service teacher professional development
2022
Vygotskian Sociocultural Theory is a powerful foundation for research into teacher professional development. However, while this research has been growing, it has largely been focused on pre-service second/foreign language. Furthermore, there is a lack of research on how the instructional process informed by the principles of Sociocultural Theory, including assessment of candidates’ mediated performance, can be orchestrated to promote teachers’ conceptual development and induce changes in their classroom practices. The present study explores how asynchronous assessment of in-service teachers’ portfolios (with the focus on lesson planning) informed by dynamic assessment framework shaped the …
Carbocysteine regulates innate immune responses and senescence processes in cigarette smoke stimulated bronchial epithelial cells
2013
Cigarette smoke represents the major risk factor for chronic obstructive pulmonary disease (COPD). Cigarette smoke extracts (CSE) alter TLR4 expression and activation in bronchial epithelial cells. Carbocysteine, an anti-oxidant and mucolytic agent, is effective in reducing the severity and the rate of exacerbations in COPD patients. The effects of carbocysteine on TLR4 expression and on the TLR4 activation downstream events are largely unknown. This study was aimed to explore whether carbocysteine, in a human bronchial epithelial cell line (16-HBE), counteracted some pro-inflammatory CSE-mediated effects. In particular, TLR4 expression, LPS binding, p21 (a senescence marker), IL-8 mRNA and…
Primary Cytomegalovirus Infection in Seronegative Kidney Transplant Patients Is Associated with Protracted Cold Ischemic Time of Seropositive Donor O…
2017
Human Cytomegalovirus (CMV) can lead to primary infection or reactivation in CMV-seronegative or -seropositive kidney transplant recipients, respectively. Complications comprise severe end-organ diseases and acute or chronic transplant rejection. Risk for CMV manifestation is stratified according to the CMV-IgG-serostatus, with donor+/recipient- (D+/R-) patients carrying the highest risk for CMV-replication. However, risk factors predisposing for primary infection in CMV-seronegative recipients are still not fully elucidated. Therefore, we monitored D+/R- high-risk patients undergoing kidney transplantation in combination with antiviral prophylaxis for the incidence of CMV-viremia for a med…
A novel epitope of N-CAM defines precursors of human adherent NK cells
2004
AbstractActivated, adherent natural killer (A-NK) cells represent a distinct subpopulation of interleukin (IL)-2-stimulated NK cells, which are selectively endowed with the increased expression of integrins and ability to adhere to solid surfaces, migrate into, infiltrate, and destroy cancerous tissues. The present study defines the phenotype and functions of precursors of A-NK (pre-A-NK) cells in humans. Peripheral blood pre-A-NK cells, in contrast to the rest of NK cells, express a novel epitope of CD56 neuronal cell adhesion molecule, termed ANK-1, and increased cell-surface levels of integrins. Pre-A-NK cells also express low levels of CD56 and CD161, and some express CD162 receptor, do…
Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion.
2013
Tumor-growth is often associated with the expansion of myeloid derived suppressor cells that lead to local or systemic arginine depletion via the enzyme arginase. It is generally assumed that this arginine deficiency induces a global shut-down of T cell activation with ensuing tumor immune escape. While the impact of arginine depletion on polyclonal T cell proliferation and cytokine secretion is well documented, its influence on chemotaxis, cytotoxicity and antigen specific activation of human T cells has not been demonstrated so far. We show here that chemotaxis and early calcium signaling of human T cells are unimpaired in the absence of arginine. We then analyzed CD8(+) T cell activation…
Role of antibiotic prophylaxis in antenatal hydronephrosis: A systematic review from the European Association of Urology/European Society for Paediat…
2017
Summary Background The benefits and harms of continuous antibiotic prophylaxis (CAP) versus observation in patients with antenatal hydronephrosis (ANH) are controversial. Objective The aim was to determine the effectiveness of CAP for ANH, and if beneficial to determine the best type and regimen of antibiotic and the most harmful to provide guidance for clinical practice. Methods A systematic literature search was performed in databases including Medline, Embase, and Cochrane in June 2015. The protocol was prospectively registered to PROSPERO (CRD42015024775). The search started from 1980, when maternal ultrasound was first introduced into clinical practice. Eligible studies were critically…