Search results for "axis"

Learning and remembering the environment in the blind cave fishAnoptichthys jordani

1989

1. The swimming behavior of blind cave fish (Anoptichthys jordani) differs in familiar and unfamiliar surroundings. Following release in unfamiliar surroundings, or after alterations of a familiar environment, the fish increase swimming velocity in order to optimize lateral line organ stimulation. Furthermore, they glide along boundary features more often than they do in familiar surroundings. These characteristics of swimming behavior were used to measure the occurrence and duration of exploratory behavior. 2. Fish removed from a familiar environment for as long as 2 days spend less time exploring when returned than when they were initially placed in the environment. After a longer absence…

Anaphylaxis caused by helminths: review of the literature.

2012

BACKGROUND: Anaphylaxis is a severe, life-threatening, generalized or systemic hypersensitivity reaction. In many individuals with anaphylaxis a pivotal role is played by IgE and the high-affinity IgE receptor on mast cells or basophils. Less commonly, it is triggered through other immunologic mechanisms, or through nonimmunologic mechanisms. The human immune response to helminth infections is associated with elevated levels of IgE, tissue eosinophilia and mastocytosis, and the presence of CD4+ T cells that preferentially produce IL-4, IL-5, and IL-13. Individuals exposed to helminth infections may have allergic inflammatory responses to parasites and parasite antigens. AIM: To summarize th…

Incidence and Management of Recurrence in Patients with Crohn's Disease Who Have Undergone Intestinal Resection: The Practicrohn Study.

2017

Background: More than 50% of patients with Crohn's disease require intestinal resection at least once. Postoperative recurrence (POR) is almost uniform if prophylactic treatment is not started early. Endoscopic monitoring is generally advised. We studied the incidence and management of recurrence in patients who had undergone intestinal resection. Methods: Practicrohn was an observational retrospective study performed in 26 Spanish hospitals including patients aged >= 18 years who underwent Crohn's disease-related ileocolonic resection between January 2007 and December 2010. We recorded preventive treatments, the incidence of clinical recurrence in daily practice, and associated risk factor…

Antifungal prophylaxis of oropharyngeal mucositis with itraconazole during adjuvant chemotherapy in colorectal cancer (CRC)patients.

2008

Three orientations for understanding educational autonomy: school principals’ voices from Australia, Finland, and Jamaica

2021

This paper reports on the findings from a multi-site case study conducted in Australia, Finland and Jamaica which explored the conditions that enabled and constrained the autonomy of school principals. Systematic data collection was carried out in the form of interviews of school principals and the data was analysed using a qualitative approach. The analysis indicates that: (1) school principals’ practices are prefigured by the peculiarities of historical trajectories and ideological traditions enmeshed in schooling sites; (2) these prefiguring arrangements in turn influence varying realisations of autonomous decision making practices across national sites; and (3) even in the expression of…

Psychological Research on Martial Artists

2012

In this article, we problematize sport psychology research on martial artists and offer some suggestions for advancing our knowledge in this area of research and practice. First, we review the previous research in the field. Then we introduce “cultural praxis” as a theoretical framework that will guide our analysis. Finally, we engage sociological studies of female fighters in conjunction with the adopted theoretical lens to outline the limitations of sport psychological research with regards to the experiences of women. It seems that the majority of the studies have used the male athlete as the norm, while research on the female athlete remains limited and focused on “differences”. Focusin…

(Re)negotiating an athlete's identity during training and researching judo in Finland

2016

Role of the IL-23/IL-17 Pathway in Rheumatic Diseases: An Overview

2021

Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19) and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12). IL-23 is mainly produced by macrophages and dendritic cells, in response to exogenous or endogenous signals, and drives the differentiation and activation of T helper 17 (Th17) cells with subsequent production of IL-17A, IL-17F, IL-6, IL-22, and tumor necrosis factor α (TNF-α). Although IL-23 plays a pivotal role in the protective immune response to bacterial and fungal infections, its dysregulation has been shown to exacerbate chronic immune-mediated inflammation. Well-established experimental data support the concept that IL-23/IL…

Leukotriene B4-loaded microspheres: a new therapeutic strategy to modulate cell activation

2008

AbstractBackgroundLeukotriene B4(LTB4) is a potent inflammatory mediator that also stimulates the immune response. In addition, it promotes polymorphonuclear leukocyte phagocytosis, chemotaxis, chemokinesis and modulates cytokines release. Regarding chemical instability of the leukotriene molecule, in the present study we assessed the immunomodulatory activities conferred by LTB4released from microspheres (MS). A previous oil-in-water emulsion solvent extraction-evaporation method was chosen to prepare LTB4-loaded MS.ResultsIn the mice cremasteric microcirculation, intraescrotal injection of 0.1 ml of LTB4-loaded MS provoked significant increases in leukocyte rolling flux, adhesion and emig…

Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled rando…

2019

Abstract Background Hereditary angioedema (HAE) is a debilitating disorder resulting from C1-esterase inhibitor (C1-INH) deficiency. In the COMPACT phase 3 study the prophylactic use of a subcutaneous C1 inhibitor (C1-INH [SC], HAEGARDA®, CSL Behring) twice weekly significantly reduced the frequency of acute edema attacks. Analysis of treatment effects by subgroups, onset of effect, and other exploratory analysis have not been reported. Methods This is a post hoc exploratory analysis on data from the randomized, placebo-controlled COMPACT study. 90 patients with C1-INH-HAE were randomized to 1 of 4 treatment sequences: C1-INH (SC) 40 or 60 IU/kg of body weight twice weekly for 16 weeks, pre…