Search results for "azoxystrobin"

showing 7 items of 7 documents

Carbon nanotube-protein carriers enhance size-dependent self-adjuvant antibody response to haptens

2013

Carbon nanotubes (CNTs) are nanomaterials with interesting emerging applications. Their properties make CNTs excellent candidates for use as new nanovehicles in drug delivery, immunization and diagnostics. In the current study, we assessed the immune-response-amplifying properties of CNTs to haptens by using azoxystrobin, the first developed strobilurin fungicide, asamodel analyte. Anazoxystrobin derivative bearingacarboxylated spacer arm (hapten AZc6) was covalently coupled to bovine serum albumin (BSA), and the resulting BSA-AZc6 conjugate was covalently linked to four functionalized CNTs of different shapes and sizes, varying in diameter and length. These four types of CNT-based construc…

Analytemedicine.medical_treatmentAzoxystrobinFreund's AdjuvantAntigen deliveryCarbon nanotubesPharmaceutical ScienceAntibodiesBiomaterialsMicechemistry.chemical_compoundMicroscopy Electron TransmissionmedicineAnimalsOrganic chemistryBovine serum albuminDrug CarriersMice Inbred BALB CbiologyNanotubes CarbonChemistrySerum Albumin BovineStrobilurinsFungicides IndustrialPyrimidinesAzoxystrobinImmunoglobulin GDrug deliverybiology.proteinBiophysicsMethacrylatesFemaleImmunizationRabbitsAntibodyHaptensAdjuvantHaptenConjugate
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Generation of anti-azoxystrobin monoclonal antibodies from regioisomeric haptens functionalized at selected sites and development of indirect competi…

2012

Azoxystrobin is a modern strobilurin fungicide used around the world to combat prime diseases affecting highly valuable crops. Accordingly, residues of this chemical are frequently found in food, even though mostly under maximum tolerated levels. We herein describe the development of an indirect competitive immunoassay for the determination of azoxystrobin residues. A panel of monoclonal antibodies displaying subnanomolar affinity to azoxystrobin was generated using, as immunizing haptens in mice, four functionalized derivatives carrying the same spacer arm located at different rationally chosen positions. This collection of antibodies was thoroughly characterized with homologous and hetero…

medicine.drug_classFungicidePolysorbatesEnzyme-Linked Immunosorbent AssayFood ContaminationMonoclonal antibodyBiochemistryFood safetyAnalytical ChemistryMicechemistry.chemical_compoundLimit of DetectionVegetablesmedicineAnimalsEnvironmental ChemistrySpectroscopyMice Inbred BALB CHybridomasChromatographybiologymedicine.diagnostic_testChemistryAntibodies MonoclonalStrobilurinsFungicides IndustrialCompetitive ELISAFungicideSite heterologyPyrimidinesAzoxystrobinFruitImmunoassayStrobilurinSolventsbiology.proteinMethacrylatesLandsteiner's principleFemaleAntibodyHaptensHaptenConjugateAnalytica Chimica Acta
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Rhizoctonia solani AG5 and Its Offspring – Morphology and Sensitivity to Fungicides

2022

The objective of these studies was to identify differences and similarities within the progeny of Rhizoctonia solani AG5, which arose from basidiospores produced by the maternal strain ID23. The following characteristics were analyzed: appearance of the mycelium (color, structure, zonation, and presence of sclerotia), growth rate (at 10°C, 20°C, and 30°C), fungicide sensitivity, and hyphal structure. The mycelial color of R. solani AG5 ranged from white/cream to light and dark brown. The structure of the mycelium may be compacted or flattened with visible zoning or fluffy with dark brown sclerotia on the colony surface. Homokaryons and heterokaryons derived from homokaryons were analyzed by…

thiophanate-methylRhizoctonia solanibasidiosporeazoxystrobinprogeny; morphologyhyphaefungicidesthiuramActa Mycologica
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Off-line coupling of multidimensional immunoaffinity chromatography and ion mobility spectrometry: A promising partnership.

2015

The extreme specificity of immunoaffinity chromatography (IAC) columns coupled to the high sensitivity of ion mobility spectrometry (IMS) measurements makes this combination really useful for rapid, selective, and sensitive determination of a high variety of analytes in different samples. The capabilities of the IAC-IMS coupling have been highlighted under three different scenarios: (i) multiclass residue analysis using a single IAC column, (ii) multiclass residue analysis using stacked IAC columns, and (iii) isomer analysis. In the first case, the determination of three strobilurin fungicides - azoxystrobin, picoxystrobin, and pyraclostrobin - in water and strawberry juice was considered, …

AnalyteIon-mobility spectrometryPyridinesAnalytical chemistryWineBiochemistryFragariaSensitivity and SpecificityChromatography AffinityAnalytical Chemistrychemistry.chemical_compoundWineResidue (complex analysis)ChromatographyElutionOrganic ChemistryWaterStereoisomerismGeneral MedicineStrobilurinsFungicides IndustrialFruit and Vegetable JuicesPyrimidineschemistryAcrylatesAzoxystrobinStrobilurinMethacrylatesPyrazolesPyrimethanilCarbamatesJournal of chromatography. A
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Synthesis of azoxystrobin transformation products and selection of monoclonal antibodies for immunoassay development

2012

The use of agrochemicals for crop protection may result in the presence of toxic residues in soils and aquatic environments, besides in foodstuffs. Most often just the parent compound is included in the definition of pesticide residue, even though chemicals resulting from biotransformation and degradation routes might also be of toxicological relevance. Azoxystrobin is a broad-spectrum systemic fungicide widely used worldwide to combat pathogenic fungi affecting plants. We herein report the synthesis and detailed chemical characterization of several of the most relevant metabolites and degradates of azoxystrobin. These compounds were further employed as ligands for screening a collection of…

medicine.drug_classStereochemistryFungicideMetaboliteGeneric antibodyEnzyme-Linked Immunosorbent AssayFood ContaminationMetaboliteBuffersToxicologyMonoclonal antibodyMicechemistry.chemical_compoundBiotransformationAntibody SpecificitymedicineAnimalsImmunoassayMolecular Structuremedicine.diagnostic_testPesticide residueChemistryAntibodies MonoclonalGeneral MedicineHydrogen-Ion ConcentrationStrobilurinsFungicides IndustrialFungicidePyrimidinesBiochemistryAzoxystrobinImmunoassayMethacrylatesDegradateHaptenImmunoanalytical methodsToxicology Letters
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Fungicide multiresidue monitoring in international wines by immunoassays

2015

24 pages, 5 figures, 1 table. -- Available online 10 November 2015.

FungicideWine01 natural sciencesAnalytical ChemistryFood safetyToxicologychemistry.chemical_compound0404 agricultural biotechnologyHumansImmunoassayWinePesticide residuebusiness.industry010401 analytical chemistryConsumer healthPesticide Residuesfood and beverages04 agricultural and veterinary sciencesGeneral MedicineResiduesPesticideContamination040401 food science0104 chemical sciencesBiotechnologyFungicideHaptenchemistryAzoxystrobinPyrimethanilELISARapid methodbusinessFood ScienceFood quality
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Reducing postharvest decay in cactus pears by dip treatment with imazalil or azoxystrobin

2019

Postharvest decay in cactus pear is a minor problem in fruit marketed directly after harvest, while it may represent a major cause of losses when fruit are cold stored or subjected to cold quarantine treatments. Unfortunately, to date, no postharvest fungicide has been registered to control postharvest decay of cactus pears. Thus, the objective of this study was to evaluate the efficacy of two globally known fungicides, imazalil (IMZ) and azoxystrobin (AZO), registered for postharvest treatment of various fresh produce species, to control decay on cactus pears. Second-crop cactus pears ‘Gialla’ fruits were dipped in 500 mg L(‑1) IMZ or AZO and stored at 1 or 8°C and 90-95% RH for 2 or 3 wee…

PEARHorticulturePesticideBiologybiology.organism_classificationlaw.inventionSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeFungicidechemistry.chemical_compoundHorticulturechemistrylawAzoxystrobinQuarantinePenicilliumCactusPostharvestazoxystrobin cactus pears decay imazalil storageActa Horticulturae
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