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showing 10 items of 2078 documents
Patients' conceptions of undergoing physiotherapy for persistent low back pain delivered in Finnish primary healthcare by physiotherapists who had pa…
2020
To explore the conceptions of patients with persistent low back pain (LBP) of undergoing physiotherapy delivered in Finnish primary healthcare by physiotherapists who had participated in brief training in Cognitive Functional Therapy (CFT).As part of a feasibility implementation study exploring CFT in management of LBP in the Finnish primary healthcare system, we interviewed nine patients from four geographical areas in Finland after receiving care. We used a phenomenographic approach to explore the variation in their conceptions.The analysis revealed four descriptive categories: "hung out to dry," "stuck," "making sense and taking control," and "holistic approach to care and living," that …
Beneficial Intervertebral Disc and Muscle Adaptations in High-Volume Road Cyclists
2019
PURPOSE: Cycling is widely practiced as a mode of transportation, a leisurely pursuit and a competitive sport. Approximately half of cyclists experience low back pain. Yet, there has been limited study of spine tissue adaptations due to cycling. METHODS: To investigate potential risk factors for spinal pain, we compared 18 high-volume cyclists (>150 km per week for ³5 years) to 18 height-matched non-sporting referents. Participants had no history of spinal pathology. Magnetic resonance imaging was used to quantify intervertebral disc (IVD) morphology and hydration; and psoas, erector spinae, quadratus lumborum and multifidus muscle size and fat content. Endurance of trunk muscles (flexors a…
Mechanical loading influences the lumbar intervertebral disc : A cross‐sectional study in 308 athletes and 71 controls
2021
There is evidence in animal populations that loading and exercise can positively impact the intervertebral disc (IVD). However, there is a paucity of information in humans. We examined the lumbar IVDs in 308 young athletes across six sporting groups (baseball, swimming, basketball, kendo, soccer and running; mean age 19yrs) and 71 non‐athletic controls. IVD status was quantified via the ratio of IVD to vertebral body height (IVD hypertrophy) and ratio of signal intensity in the nucleus to that in the annulus signal (IVD nucleus hydration) on sagittal T2‐weighted MRI. P‐values were adjusted via the false discovery rate method to mitigate false positives. In examining the whole collective, co…
Exploring the Interpersonal Level of Music Performance Anxiety : Online Listener’s Accuracy in Detecting Performer Anxiety
2022
Music performance anxiety (MPA) affects musicians at various stages of a performance, from its preparation until the aftermath of its delivery. Given the commonality and potentially grave consequences of MPA, it is understandable that much attention has been paid to the musician experiencing it. Consequently, we have learned a great deal about the intrapersonal level of MPA: how to measure it, treatments, experimental manipulations, and subjective experiences. However, MPA may also manifest at an interpersonal level by influencing how the performance is perceived. Yet, this has not yet been measured. This exploratory online study focuses on the listener’s perception of anxiety and compares …
Communicating through ancillary gestures: Exploring effects on coperformers and audiences
2020
Musicians make elaborate movements while performing, often using gestures that might seem extraneous. To explore these movements, we motion-captured and audio-recorded different pairings of clarinetists and pianists performing Brahms’ Clarinet Sonata No. 1 with two manipulations: (a) allowing the performers full vs. no visual feedback, and (b) allowing the performers full vs. partial auditory feedback (i.e., the clarinetist could not hear the pianist). We found that observer ratings of audio–visual point-light renditions discriminated between manipulations and refined this insight through subsequent audio-alone and visual-alone experiments, providing an understanding of each modality’s cont…
Open-label ODYSSEY APPRISE study: Interim data from the first 843 participants
2018
Background PCSK9 inhibitors (PCSK9i) have been recommended by the ESC/EAS Task Force in very high risk subjects with ASCVD and those with heterozygous familial hypercholesterolemia (HeFH) with persistent high LDL-C levels despite maximally tolerated LLT. Purpose ODYSSEY APPRISE (NCT02476006) is the first study to assess efficacy and safety at Week (W) 12 of the PCSK9i alirocumab (ALI) in a real-life setting prior to commercial availability. Methods APPRISE was an open-label, single-arm study, conducted in 16 European countries and Canada. Subjects with inadequately controlled lipid levels despite maximally tolerated LLT were included. Based on physician's judgment, participants received eit…
Processing of an Audiobook in the Human Brain Is Shaped by Cultural Family Background
2022
Funding Information: Funding: This work was supported by the Academy of Finland [257811, 273469, 276643, 287474, 332309]; Jane and Aatos Erkko Foundation; Emil Aaltonen Foundation; Paulo Foundation and Russian Science Foundation grant [No: 22-48-08002]. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. Perception of the same narrative can vary between individuals depending on a listener’s previous experiences. We studied whether and how cultural family background may shape the processing of an audiobook in the human brain. During functional magnetic resonance imaging (fMRI), 48 healthy volunteers from two different cultural family backgrounds listened to an audi…
Joseph Conrad's Adventure With English
2022
This article discusses Conrad’s Anglophone linguistic identity to show how writing became his “promised land” and fictional homeplace. This fictional retreat reflects his childhood experience, (connected with his Polish background), hopes, and fears, but it is likewise refracted through episodes of his later life. Conrad’s own articulation of his complex relation to English, England, and his own nationality, reveals his outlook on literature and language: “When speaking, writing or thinking in English the word Home always means for me the hospitable shores of Great Britain” (Collected Letters 1:12) and “Both at sea and on land, my point of view is English, from which the conclusion should n…
Mental fatigue induced by prolonged self-regulation does not exacerbate central fatigue during subsequent whole-body endurance exercise
2015
International audience; It has been shown that the mental fatigue induced by prolonged self-regulation increases perception of effort and reduces performance during subsequent endurance exercise. However, the physiological mechanisms underlying these negative effects of mental fatigue are unclear. The primary aim of this study was to test the hypothesis that mental fatigue exacerbates central fatigue induced by whole-body endurance exercise. Twelve subjects performed 30 min of either an incongruent Stroop task to induce a condition of mental fatigue or a congruent Stroop task (control condition) in a random and counterbalanced order. Both cognitive tasks (CTs) were followed by a whole-body …
Unsupervised representation learning of spontaneous MEG data with nonlinear ICA
2023
Funding Information: We wish to thank the reviewers and editors for the useful comments to improve the paper a lot. We thank Dr. Hiroshi Morioka for the useful discussion at the beginning of the project. L.P. was funded in part by the European Research Council (No. 678578 ). A.H. was supported by a Fellowship from CIFAR, and the Academy of Finland. The authors acknowledge the computational resources provided by the Aalto Science-IT project, and also wish to thank the Finnish Grid and Cloud Infrastructure (FGCI) for supporting this project with computational and data storage resources. | openaire: EC/H2020/678578/EU//HRMEG Resting-state magnetoencephalography (MEG) data show complex but stru…